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2 "Giant cell tumors"
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Case Reports
Osteoclast-like Giant Cell Tumor of Parotid Gland with a Carcinomatous Component: A Case Report
Jung Wook Yang, Hyeon Cheol Kim, Jeong Hee Lee, Jong Sil Lee, Dong Chul Kim, Dae Hyun Song, Jin Pyeong Kim, Gyung Hyuck Ko
Korean J Pathol. 2012;46(3):297-301.   Published online June 22, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.3.297
  • 6,820 View
  • 56 Download
  • 5 Crossref
AbstractAbstract PDF

The giant cell tumor of the salivary gland is very rare, and 20 cases have been reported in the English-language literature. We report an additional case. A 57-year old man had noticed a mass in the right parotid area for several weeks. The diagnosis using aspiration cytology was a giant cell tumor possibly with a carcinomatous component. Superficial parotidectomy was carried out. The resected parotid gland contained a 1.8 cm-sized well-circumscribed brownish tumor. Histologically the tumor consisted of evenly distributed osteoclast-like giant cells, mononuclear cells and two small foci of a carcinomatous component. The osteoclast-like giant cells and mononuclear cells were positive for vimentin and CD68, and the carcinomatous component was positive for cytokeratin and epithelial membrane antigen. There was no metastatic lesion in the cervical lymph nodes. We believe this is the first case in Korea of an osteoclast-like giant cell tumor of the parotid gland.

Citations

Citations to this article as recorded by  
  • Genomic alteration in rare subtype of sarcomatoid salivary duct carcinoma
    Ji-Seon Jeong, Kyung-Ja Cho, Deokhoon Kim, Yoon Se Lee, Joon Seon Song
    Pathology - Research and Practice.2021; 228: 153678.     CrossRef
  • Giant cell tumor of temporomandibular joint presenting as a parotid tumor: Challenges in the accurate subclassification of giant cell tumors in an unusual location
    Rongqin Ren, Sandra Mueller, Adele O. Kraft, Celeste N. Powers
    Diagnostic Cytopathology.2018; 46(4): 340.     CrossRef
  • Osteoclast‐Like Giant Cell Tumor of the Parotid Gland: Report of a Case Diagnosed on Fine‐Needle Aspiration Cytology With Histological and Immunohistochemical Findings
    Poonam Elhence, Meenakshi Rao, Amit Goyal, Amit Kumar, Pushpinder S. Khera, Shilajit Bhattacharya
    Diagnostic Cytopathology.2016; 44(6): 548.     CrossRef
  • Giant cell tumour of a temporomandibular joint presenting as a parotid mass: Case report and analysis of the 19 cases in the literature
    Yun-Chen Huang, Jeng-Wen Chen, Yen-Lin Chen, Pei-Jen Lou
    Journal of Cranio-Maxillofacial Surgery.2014; 42(8): 1778.     CrossRef
  • Tumeur à cellules géantes de type ostéoclastique de la parotide
    S. Rammeh, I. Hergli, M.K. M’farrej, N. Znaidi, S. Nechi, R. Zermani
    Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale.2014; 115(3): 185.     CrossRef
Giant Cell Tumor-like Proliferation Associated with Renal Staghorn Calculi: A Case Report.
Han Seong Kim, Mee Joo, Sun Hee Chang, Ji Eun Kwak, Sang Hwa Shim, Sung Yong Cho
Korean J Pathol. 2009;43(2):182-184.
DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.2.182
  • 2,768 View
  • 21 Download
  • 1 Crossref
AbstractAbstract PDF
A 62-year-old man with left flank pain and hematuria was shown to have a staghorn stone in left renal pelvis. Grossly, renal pelvis and calyces were markedly dilated with cystic and hemorrhagic degeneration and renal parenchyma was atrophied. A tumor-like mass was located in a hemorrhagic cyst of the renal upper pole. This mass consisted of giant cells and stromal cells mimicking a giant cell tumor of bone. This giant cell tumor-like proliferation may represent a response to hemorrhage into a cystic cavity. Recognition of this finding is important to avoid the over-diagnosis of neoplastic lesions.

Citations

Citations to this article as recorded by  
  • Imaged guided surgery during arteriovenous malformation of gastrointestinal stromal tumor using hyperspectral and indocyanine green visualization techniques: A case report
    Tristan Wagner, Onur Mustafov, Marielle Hummels, Anders Grabenkamp, Michael N Thomas, Lars Mortimer Schiffmann, Christiane J Bruns, Dirk L Stippel, Roger Wahba
    World Journal of Clinical Cases.2023; 11(23): 5530.     CrossRef

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