Journal of Pathology and Translational Medicine

Case Study

Spindle cell oncocytoma of the sella turcica with anaplastic features and rapid progression in short-term follow-up: a case report with proposal of distinctive radiologic features: Dong Ja Kim, SangHan Lee, Mee-seon Kim, Jeong-Hyun Hwang, Myong Hun Hahm; J Pathol Transl Med. 2021;55(3):225-229. Published online March 9, 2021; DOI: https://doi.org/10.4132/jptm.2021.01.27

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We present a rare case of spindle cell oncocytoma (SCO) of the sella turcica with malignant histologic features and rapid progression. A 42-year-old woman experienced bilateral blurred vision and was preoperatively misdiagnosed as having a pituitary macroadenoma on magnetic resonance imaging. After surgery, SCO was diagnosed by the histopathologic features of interlacing fascicles of spindle tumor cells with finely granular, eosinophilic cytoplasm. Focal anaplastic changes and necrosis were present. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen, S-100, galectin-3, and thyroid transcription factor 1. Four months later, the tumor had progressed, and second surgery with adjuvant radiotherapy was performed; the patients remains under observation. In this report, we proposed distinctive radiologic features for differential diagnosis between SCO and other pituitary tumors.

Citations

Citations to this article as recorded by

Treatment modalities and outcomes of granular cell tumors and spindle cell oncocytomas of the pituitary gland: an analysis of two national cancer databases
A. Yohan Alexander, Giorgos Michalopoulos, Panagiotis Kerezoudis, Jamie J. Van Gompel, Michael J. Link, Maria Peris-Celda
Acta Neurochirurgica.2024;[Epub] CrossRef
Spindle cell oncocytoma, a misdiagnosed rare entity of the pituitary – A case report with review of literature and special emphasis on the morphological differentials
Gittwa Vatsaraj Kottangal, Lilly Madhavan, Shalini Kuruvilla, Kavitha Kanjirakadu Parameswaran, Shehla Basheer Kollathodi
Indian Journal of Pathology and Oncology.2021; 8(4): 533. CrossRef

Case Report

Hemorrhagic Pseudocyst of the Adrenal Gland: A case report.: Kyoung Mee Kim, Anhi Lee, Kyung Myung Sohn, Seung Man Park, Sang In Shim; Korean J Pathol. 1998;32(7):543-545.

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Abstract: Adrenal pseudocysts are rare benign cystic lesions resulting from a hemorrhage into a normal parenchyme of the adrenal gland. Although the frequency of adrenal cysts are increasing due to improved radiologic imaging techniques, only two cases have been reported in Korean literatures. A 63-year-old man was presented with a 10-year history of a mass in the right abdomen. Abdominal computed tomogram and a magnetic resonance image study showed a 9 cm sized well defined heterogeneous low attenuated mass in the right suprarenal area. Gross examination revealed an ovoid rubbery mass measuring 10 9 8 cm and weighing 355 gm. The content of this lesion was tan to deep brown, necrotic, and creamy with myxoid areas. Histologic examination revealed compressed, thin layers of adrenal cortex embedded in the fibrous tissue, and the cystic contents were eosinophilic fibrinoid materials with a few dilated cavernous vascular spaces lined by endothelial cells.

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