Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
© 2017 The Korean Society of Pathologists/The Korean Society for Cytopathology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Conflicts of Interest
No potential conflict of interest relevant to this article was reported.
Non-maligGro, resected specimen requiring gross sectioning; NPB, number of paraffin blocks; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; HR, examination of hormone receptor in tissue; CERVIX, cervicovaginal cytopathology; L-, liquid based; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2 (FISH), HER2 gene fluorescence in situ hybridization; HER2 (SISH), HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Values are presented as number (%).
Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2, HER2 gene fluorescence in situ hybridization and HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Values are presented as number (%).
Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy
Values are presented as number (%).
ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2, HER2 gene fluorescence in situ hybridization and HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Values are presented as number (%).
Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2, HER2 gene fluorescence in situ hybridization and HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Values are presented as number (%).
Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy.
Values are presented as number (%).
ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2, HER2 gene fluorescence in situ hybridization and HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Values are presented as number (%).
Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2, HER2 gene fluorescence in situ hybridization and HER2 gene silver in situ hybridization; MSI, microsatellite instability; OUTSIDE, outside slide interpretation.
Main category | Subcategory | Claim codes |
---|---|---|
Biopsy | 1–3 pieces/4–6 pieces/7–9 pieces/10–12 pieces/more than 13 pieces | C5911/C5912/C5913/C5914/C5915 |
Non-maligGro | NPB ≤ 6/NPB ≥ 7 | C5916/C5917 |
MaligGro LND | NPB ≤ 20/NPB ≥ 21 | C5918/C5919 |
MaligGro LNDX | NPB ≤ 15/NPB ≥ 16 | C5500/C5504 |
MAPPING | LND/LNDX | C5505/C5508 |
FS | 1–2 specimens/3–6 specimens/7–10 specimens/equal and more than 11 specimens | C5511/C5512/C5513/C5514 |
BONE | - | C5520 |
SPECIAL | Reticulin/Massons’ Trichrome/others | C5531/C5532/C5533 |
IF | IgG/IgA/IgM/IgE/C3/C4/HBsAg/fibrinogen/others | C5541/C5542/C5543/C5544/C5545/C5549/C5546/C5547/C5548 |
EM | - | C5550 |
ENZYME | ATPase-pH 9.4/ATPase-pH 4.9/NADH/acetylcholinesterase/chloroacetate esterase/others | C5561/C5562/C5563/C5564/C5565/C5566 |
Etc. | Et cetera | - |
IHC | Interpretation by qualified doctor | C5575006 |
Interpretation by non-qualified doctor | C5575 | |
HR | C5590 | |
EGFR pharmDx kit | CZ503006 | |
Morphometric Analysis | CY552 | |
CERVIX | Smear/L-based | C5920/CX541 |
BFC | General/using cytospin examination/L-based | C5930/C5931/CZ521 |
AC | Conventional/L-AC | C5941/C5943 |
CB | After BFC/after AC/L-AC | C5940/C5942/C5944 |
HER2 (FISH) | - | C5967 |
HER2 (SISH) | - | CZ988 |
MSI test | - | CX574 |
OUTSIDE | - | Claim code + 009 (subnumber) |
Main category | 2011 | 2012 | 2013 | 2014 | 2015 | Total | Growth rates (%) by 2011 | Slope | Adjusted R-squared | p-value |
---|---|---|---|---|---|---|---|---|---|---|
Biopsy | 2,084,502 (20.24) | 2,092,015 (20.31) | 2,086,267 (20.25) | 2,052,391 (19.92) | 1,985,718 (19.28) | 10,300,893 (100) | –4.7 | –23,719.2 | .617 | .072 |
Non-maligGro | 1,269,834 (18.90) | 1,371,044 (20.41) | 1,349,030 (20.08) | 1,340,151 (19.95) | 1,388,338 (20.66) | 6,718,397 (100) | 9.3 | 20,611.5 | .354 | .172 |
MaligGro LND | 100,204 (20.04) | 106,599 (21.32) | 107,083 (21.42) | 97,288 (19.46) | 88,838 (17.77) | 500,012 (100) | –11.3 | –3,204.3 | .273 | .212 |
MaligGro LNDX | 40,003 (18.99) | 41,651 (19.77) | 42,958 (20.39) | 43,528 (20.66) | 42,553 (20.20) | 210,693 (100) | 6.4 | 697.7 | .524 | .103 |
MAPPING | 28,429 (15.16) | 35,866 (19.12) | 38,546 (20.55) | 42,042 (22.42) | 42,662 (22.75) | 187,545 (100) | 50.1 | 3,464.2 | .867 | .014 |
FS | 111,477 (20.19) | 116,373 (21.08) | 114,943 (20.82) | 107,726 (19.51) | 101,583 (18.40) | 552,102 (100) | –8.9 | –2,843.5 | .424 | .141 |
BONE | 15,705 (21.11) | 15,267 (20.52) | 14,275 (19.19) | 14,516 (19.51) | 14,643 (19.68) | 74,406 (100) | –6.8 | –287.5 | .462 | .126 |
SPECIAL | 362,898 (19.53) | 364,742 (19.63) | 372,751 (20.07) | 385,799 (20.77) | 371,494 (20.00) | 1,857,684 (100) | 2.4 | 3,824.9 | .266 | .216 |
IF | 59,173 (18.40) | 63,043 (19.60) | 64,959 (20.20) | 66,347 (20.63) | 68,110 (21.18) | 321,632 (100) | 15.1 | 2,117.8 | .939 | .004 |
EM | 8,945 (19.07) | 9,344 (19.92) | 9,452 (20.15) | 9,522 (20.30) | 9,637 (20.55) | 46,900 (100) | 7.7 | 156.2 | .821 | .022 |
ENZYME | 2,399 (27.80) | 1,901 (22.03) | 1,437 (16.65) | 1,479 (17.14) | 1,415 (16.39) | 8,631 (100) | –41 | –239 | .717 | .044 |
IHC | 550,773 (17.15) | 610,637 (19.01) | 653,438 (20.34) | 698,083 (21.73) | 699,285 (21.77) | 3,212,216 (100) | 27 | 38,447 | .909 | .008 |
CERVIX | 209,750 (17.67) | 224,052 (18.88) | 226,773 (19.11) | 245,152 (20.65) | 281,166 (23.69) | 1,186,893 (100) | 34 | 16,393.2 | .849 | .017 |
BFC | 490,524 (18.99) | 514,410 (19.92) | 511,839 (19.82) | 530,399 (20.54) | 535,708 (20.74) | 2,582,880 (100) | 9.2 | 10,635.7 | .861 | .015 |
AC | 292,502 (21.91) | 314,290 (23.55) | 294,545 (22.07) | 231,264 (17.33) | 202,235 (15.15) | 1,334,836 (100) | –30.9 | –26,356 | .683 | .053 |
CB | 117,159 (21.76) | 115,878 (21.52) | 112,949 (20.98) | 103,139 (19.15) | 89,320 (16.59) | 538,445 (100) | –23.8 | –6,841.7 | .817 | .023 |
HER2 | 0 (NA) | 0 (NA) | 1,176 (10.28) | 5,031 (43.96) | 5,238 (45.77) | 11,445 (100) | NA | 1,550.7 | .814 | .023 |
MSI | 11,837 (20.56) | 10,763 (18.70) | 10,831 (18.81) | 11,919 (20.70) | 12,219 (21.22) | 57,569 (100) | 3.2 | 192 | –.060 | .444 |
OUTSIDE | 65,609 (18.04) | 72,877 (20.04) | 75,695 (20.81) | 76,649 (21.07) | 72,906 (20.04) | 363,736 (100) | 11.1 | 1,836.6 | .267 | .215 |
Requesting department | Biopsy | Non-maligGro | MaligGro LND | MaligGro LNDX | MAPPING | FS | BONE | SPECIAL | IF | EM |
---|---|---|---|---|---|---|---|---|---|---|
General | 1,983 (0.02) | 1,891 (0.03) | 5 (<0.01) | 2 (<0.01) | 0 | 0 | 3 (<0.01) | 74 (<0.01) | 0 | 0 |
Internal medicine | 6,743,794 (65.47) | 2,094,401 (31.17) | 10,822 (2.16) | 12,804 (6.08) | 101,570 (54.16) | 17,044 (3.09) | 36,536 (49.10) | 1,347,183 (72.52) | 219,154 (68.14) | 30,851 (65.78) |
Neurology | 26,860 (0.26) | 9,082 (0.14) | 78 (0.02) | 205 (0.10) | 50 (0.03) | 573 (0.10) | 174 (0.23) | 10,438 (0.56) | 834 (0.26) | 1,083 (2.31) |
Psychiatry | 7,026 (0.07) | 1,895 (0.03) | 11 (<0.01) | 12 (0.01) | 14 (0.01) | 32 (0.01) | 13 (0.02) | 1,245 (0.07) | 107 (0.03) | 9 (0.02) |
General surgery | 1,309,516 (12.71) | 1,679,607 (25.00) | 379,207 (75.84) | 73,301 (34.79) | 57,975 (30.91) | 298,270 (54.02) | 406 (0.55) | 193,095 (10.39) | 36,140 (11.24) | 5,525 (11.78) |
Orthopedic surgery | 128,100 (1.24) | 452,910 (6.74) | 649 (0.13) | 6,321 (NA) | 249 (0.13) | 15,707 (2.84) | 26,557 (35.69) | 19,256 (1.04) | 582 (0.18) | 287 (0.61) |
Neurosurgery | 56,583 (0.55) | 181,773 (2.71) | 347 (0.07) | 13,422 (6.37) | 35 (0.02) | 29,625 (5.37) | 2,979 (NA) | 18,216 (0.98) | 673 (0.21) | 3,672 (7.83) |
Thoracic surgery | 28,438 (0.28) | 100,518 (1.50) | 34,694 (6.94) | 11,248 (5.34) | 2,892 (1.54) | 48,875 (8.85) | 261 (0.35) | 33,537 (1.81) | 209 (0.06) | 122 (0.26) |
Plastic surgery | 8,598 (0.08) | 110,218 (1.64) | 1,916 (0.38) | 8,022 (3.81) | 1,337 (0.71) | 14,533 (2.63) | 420 (0.56) | 4,498 (0.24) | 98 (0.03) | 56 (0.12) |
Anesthesiology | 1,038 (0.01) | 835 (0.01) | 10 (<0.01) | 8 (<0.01) | 1 (<0.01) | 20 (<0.01) | 5 (0.01) | 110 (0.01) | 2 (<0.01) | 0 |
Obstetrics and gynecology | 888,109 (8.62) | 1,078,597 (16.05) | 26,431 (5.29) | 16,294 (7.73) | 4,194 (2.24) | 43,154 (7.82) | 53 (0.07) | 16,801 (0.90) | 136 (0.04) | 152 (0.32) |
Pediatrics | 37,839 (0.37) | 16,037 (0.24) | 118 (0.02) | 388 (0.18) | 23 (0.01) | 1,309 (0.24) | 3,856 (5.18) | 23,871 (1.28) | 16,039 (4.99) | 3,784 (8.07) |
Ophthalmology | 20,154 (0.20) | 22,715 (0.34) | 36 (0.01) | 611 (0.29) | 10 (0.01) | 1,317 (0.24) | 14 (0.02) | 3,399 (0.18) | 132 (0.04) | 85 (0.18) |
Otorhinolaryngology | 123,136 (1.20) | 396,701 (5.90) | 31,590 (6.32) | 17,180 (8.15) | 464 (0.25) | 50,489 (9.14) | 148 (0.20) | 46,797 (2.52) | 254 (0.08) | 197 (0.42) |
Dermatology | 340,839 (3.31) | 222,969 (3.32) | 121 (0.02) | 4,481 (2.13) | 472 (0.25) | 5,487 (0.99) | 9 (0.01) | 80,731 (4.35) | 41,682 (12.96) | 70 (0.15) |
Urology | 286,191 (2.78) | 215,571 (3.21) | 12,449 (2.49) | 45,382 (21.54) | 17,938 (9.56) | 22,137 (4.01) | 70 (0.09) | 15,361 (0.83) | 1,916 (0.60) | 542 (1.16) |
Radiology | 89,520 (0.87) | 7,732 (0.12) | 1 (<0.01) | 2 (<0.01) | 1 (<0.01) | 4 (<0.01) | 300 (0.40) | 1,113 (0.06) | 0 | 4 (0.01) |
Radiation oncology | 2,430 (0.02) | 113 (<0.01) | 0 | 0 | 0 | 1 (<0.01) | 0 | 202 (0.01) | 8 (<0.01) | 1 (<0.01) |
Pathology | 391 (<0.01) | 15 (<0.01) | 0 | 0 | 0 | 3 (<0.01) | 0 | 3,249 (0.17) | 19 (0.01) | 4 (0.01) |
Laboratory medicine | 338 (<0.01) | 46 (<0.01) | 0 | 0 | 0 | 0 | 24 (0.03) | 921 (0.05) | 0 | 1 (<0.01) |
Tuberculosis | 233 (<0.01) | 20 (<0.01) | 0 | 0 | 0 | 0 | 6 (0.01) | 122 (0.01) | 0 | 0 |
Rehabilitation medicine | 8,784 (0.09) | 4,392 (0.07) | 37 (0.01) | 181 (0.09) | 30 (0.02) | 385 (0.07) | 104 (0.14) | 2,131 (0.11) | 500 (0.16) | 135 (0.29) |
Nuclear medicine | 118 (<0.01) | 15 (<0.01) | 0 | 0 | 1 (<0.01) | 0 | 0 | 82 (<0.01) | 0 | 0 |
Family medicine | 146,907 (1.43) | 49,855 (0.74) | 31 (0.01) | 17 (0.01) | 240 (0.13) | 62 (0.01) | 23 (0.03) | 26,784 (1.44) | 263 (0.08) | 10 (0.02) |
Emergency medicine | 15,072 (0.15) | 6,035 (0.09) | 166 (0.03) | 190 (0.09) | 41 (0.02) | 276 (0.05) | 97 (0.13) | 5,778 (0.31) | 1,381 (0.43) | 309 (0.66) |
Occupational and environmental medicine | 1,876 (0.02) | 98 (<0.01) | 0 | 0 | 0 | 0 | 1 (<0.01) | 63 (<0.01) | 0 | 0 |
Preventive medicine | 1,394 (0.01) | 4,229 (0.06) | 0 | 0 | 2 (<0.01) | 0 | 0 | 3 (<0.01) | 0 | 0 |
Dental department | 25,596 (0.25) | 60,112 (0.89) | 1,293 (0.26) | 622 (0.30) | 6 (<0.01) | 2,799 (0.51) | 2,347 (3.15) | 2,624 (0.14) | 1,503 (0.47) | 1 (<0.01) |
Etc. | 30 (<0.01) | 15 (<0.01) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Summary | 10,300,893 (100) | 6,718,397 (100) | 500,012 (100) | 210,693 (100) | 187,545 (100) | 552,102 (100) | 74,406 (100) | 1,857,684 (100) | 321,632 (100) | 46,900 (100) |
Requesting department | ENZYME | IHC | CERVIX | BFC | AC | CB | HER2 | MSI | OUTSIDE | Summary |
---|---|---|---|---|---|---|---|---|---|---|
General | 0 | 5 (<0.01) | 363 (0.03) | 275 (0.01) | 846 (0.06) | 13 (<0.01) | 1 (0.01) | 0 | 0 | 5,461 (0.02) |
Internal medicine | 2,324 (26.93) | 897,900 (27.95) | 36,501 (3.08) | 1,259,857 (48.78) | 622,477 (46.63) | 369,897 (68.70) | 2,622 (22.91) | 3,317 (5.76) | 108,745 (29.90) | 13,917,799 (46.29) |
Neurology | 2,312 (26.79) | 5,100 (0.16) | 1,412 (0.12) | 53,245 (2.06) | 2,423 (0.18) | 1,852 (0.34) | 5 (0.04) | 8 (0.01) | 148 (0.04) | 115,882 (0.39) |
Psychiatry | 8 (0.09) | 391 (0.01) | 666 (0.06) | 2,330 (0.09) | 435 (0.03) | 153 (0.03) | 1 (0.01) | 2 (<0.01) | 24 (0.01) | 14,374 (0.05) |
General surgery | 139 (1.61) | 1,413,101 (43.99) | 6,204 (0.52) | 104,518 (4.05) | 489,190 (36.65) | 49,603 (9.21) | 8,311 (72.62) | 53,777 (93.41) | 177,028 (48.67) | 6,334,913 (21.07) |
Orthopedic surgery | 321 (3.72) | 34,131 (1.06) | 3,285 (0.28) | 35,414 (1.37) | 12,788 (0.96) | 3,055 (0.57) | 13 (0.11) | 7 (0.01) | 3,004 (0.83) | 742,636 (2.47) |
Neurosurgery | 186 (2.16) | 95,260 (2.97) | 1,915 (0.16) | 35,088 (1.36) | 3,349 (0.25) | 2,957 (0.55) | 23 (0.20) | 8 (0.01) | 825 (0.23) | 446,936 (1.49) |
Thoracic surgery | 6 (0.07) | 91,268 (2.84) | 314 (0.03) | 42,808 (1.66) | 3,034 (0.23) | 13,872 (2.58) | 30 (0.26) | 92 (0.16) | 7,707 (2.12) | 419,925 (1.40) |
Plastic surgery | 91 (1.05) | 24,684 (0.77) | 107 (0.01) | 991 (0.04) | 482 (0.04) | 388 (0.07) | 130 (1.14) | 2 (<0.01) | 1,254 (0.34) | 177,825 (0.59) |
Anesthesiology | 0 | 58 (<0.01) | 70 (0.01) | 371 (0.01) | 135 (0.01) | 31 (0.01) | 0 | 0 | 5 (<0.01) | 2,699 (0.01) |
Obstetrics and gynecology | 17 (0.20) | 152,242 (4.74) | 1,099,372 (92.63) | 56,916 (2.20) | 28,236 (2.12) | 14,401 (2.67) | 21 (0.18) | 203 (0.35) | 19,467 (5.35) | 3,444,796 (11.46) |
Pediatrics | 2,489 (28.84) | 31,051 (0.97) | 116 (0.01) | 38,929 (1.51) | 1,821 (0.14) | 1,494 (0.28) | 0 | 4 (0.01) | 1,258 (0.35) | 180,426 (0.60) |
Ophthalmology | 63 (0.73) | 10,629 (0.33) | 59 (<0.01) | 1,608 (0.06) | 848 (0.06) | 364 (0.07) | 1 (0.01) | 0 | 384 (0.11) | 62,429 (0.21) |
Otorhinolaryngology | 4 (0.05) | 125,340 (3.90) | 460 (0.04) | 9,871 (0.38) | 83,493 (6.25) | 27,339 (5.08) | 1 (0.01) | 7 (0.01) | 21,799 (5.99) | 935,270 (3.11) |
Dermatology | 197 (2.28) | 77,791 (2.42) | 308 (0.03) | 4,179 (0.16) | 3,150 (0.24) | 219 (0.04) | 7 (0.06) | 0 | 4,957 (1.36) | 787,669 (2.62) |
Urology | 9 (0.10) | 193,693 (6.03) | 26,181 (2.21) | 876,070 (33.92) | 31,351 (2.35) | 11,392 (2.12) | 4 (0.03) | 24 (0.04) | 13,370 (3.68) | 1,769,651 (5.89) |
Radiology | 2 (0.02) | 33,526 (1.04) | 298 (0.03) | 1,356 (0.05) | 31,699 (2.37) | 23,850 (4.43) | 254 (2.22) | 1 (<0.01) | 856 (0.24) | 190,519 (0.63) |
Radiation oncology | 0 | 915 (0.03) | 3,773 (0.32) | 100 (<0.01) | 155 (0.01) | 256 (0.05) | 1 (0.01) | 9 (0.02) | 1,367 (0.38) | 9,331 (0.03) |
Pathology | 1 (0.01) | 81 (<0.01) | 1 (<0.01) | 206 (0.01) | 3,255 (0.24) | 3,488 (0.65) | 1 (0.01) | 0 | 10 (<0.01) | 10,724 (0.04) |
Laboratory medicine | 0 | 7,006 (0.22) | 112 (0.01) | 22 (<0.01) | 5 (<0.01) | 2 (<0.01) | 0 | 0 | 3 (<0.01) | 8,480 (0.03) |
Tuberculosis | 0 | 75 (<0.01) | 10 (<0.01) | 1,276 (0.05) | 43 (<0.01) | 87 (0.02) | 0 | 0 | 61 (0.02) | 1,933 (0.01) |
Rehabilitation medicine | 392 (4.54) | 1,884 (0.06) | 648 (0.05) | 6,636 (0.26) | 606 (0.05) | 940 (0.17) | 10 (0.09) | 8 (0.01) | 65 (0.02) | 27,868 (0.09) |
Nuclear medicine | 0 | 62 (<0.01) | 7 (<0.01) | 44 (<0.01) | 2,514 (0.19) | 682 (0.13) | 0 | 0 | 58 (0.02) | 3,583 (0.01) |
Family medicine | 5 (0.06) | 3,524 (0.11) | 2,536 (0.21) | 16,582 (0.64) | 11,341 (0.85) | 4,132 (0.77) | 1 (0.01) | 5 (0.01) | 398 (0.11) | 262,716 (0.87) |
Emergency medicine | 64 (0.74) | 3,939 (0.12) | 2,156 (0.18) | 31,115 (1.20) | 514 (0.04) | 7,460 (1.39) | 8 (0.07) | 95 (0.17) | 293 (0.08) | 74,989 (0.25) |
Occupational and environmental medicine | 0 | 18 (<0.01) | 1 (<0.01) | 159 (0.01) | 81 (0.01) | 2 (<0.01) | 0 | 0 | 1 (<0.01) | 2,300 (0.01) |
Preventive medicine | 0 | 5 (<0.01) | 2 (<0.01) | 24 (<0.01) | 188 (0.01) | 0 | 0 | 0 | 1 (<0.01) | 5,848 (0.02) |
Dental department | 1 (0.01) | 8,537 (0.27) | 15 (<0.01) | 2,875 (0.11) | 372 (0.03) | 516 (0.10) | 0 | 0 | 648 (0.18) | 109,867 (0.37) |
Etc. | 0 | 0 | 1 (<0.01) | 15 (<0.01) | 5 (<0.01) | 0 | 0 | 0 | 0 | 66 (<0.01) |
Summary | 8,631 (100) | 3,212,216 (100) | 1,186,893 (100) | 2,582,880 (100) | 1,334,836 (100) | 538,445 (100) | 11,445 (100) | 57,569 (100) | 363,736 (100) | 30,066,915 (100) |
Pathologic examination | Tertiary hospital | General hospital | Hospital | Convalescent hospital | Clinic | Dental hospital | Dental clinic | Public health center | Public health center and county hospital | Oriental hospital | Summary |
---|---|---|---|---|---|---|---|---|---|---|---|
Biopsy | 2,354,632 (22.86) | 2,617,426 (25.41) | 1,387,062 (13.47) | 13,460 (0.13) | 3,910,624 (37.96) | 13,285 (0.13) | 898 (0.01) | 0 | 2,767 (0.03) | 739 (0.01) | 10,300,893 (100) |
Non-maligGro | 1,727,593 (25.71) | 2,362,797 (35.17) | 1,161,784 (17.29) | 3,929 (0.06) | 1,440,209 (21.44) | 18,397 (0.27) | 384 (0.01) | 0 | 2,197 (0.03) | 1,107 (0.02) | 6,718,397 (100) |
MaligGro LND | 332,395 (66.48) | 149,342 (29.87) | 13,548 (2.71) | 2 (<0.01) | 4,032 (0.81) | 693 (0.14) | 0 | 0 | 0 | 0 | 500,012 (100) |
MaligGro LNDX | 151,392 (71.85) | 56,436 (26.79) | 1,999 (0.95) | 16 (0.01) | 567 (0.27) | 282 (0.13) | 0 | 0 | 1 (<0.01) | 0 | 210,693 (100) |
MAPPING | 132,776 (70.80) | 52,851 (28.18) | 1,705 (0.91) | 7 (<0.01) | 205 (0.11) | 1 (<0.01) | 0 | 0 | 0 | 0 | 187,545 (100) |
FS | 388,171 (70.31) | 158,797 (28.76) | 3,730 (0.68) | 21 (<0.01) | 104 (0.02) | 1,279 (0.23) | 0 | 0 | 0 | 0 | 552,102 (100) |
BONE | 35,926 (48.28) | 27,499 (36.96) | 9,264 (12.45) | 5 (0.01) | 333 (0.45) | 1,378 (1.85) | 1 (<0.01) | 0 | 0 | 0 | 74,406 (100) |
SPECIAL | 817,633 (44.01) | 756,183 (40.71) | 57,218 (3.08) | 778 (0.04) | 224,562 (12.09) | 1,301 (0.07) | 0 | 0 | 1 (<0.01) | 8 (<0.01) | 1,857,684 (100) |
IF | 226,147 (70.31) | 91,857 (28.56) | 519 (0.16) | 503 (0.16) | 1,450 (0.45) | 1,156 (0.36) | 0 | 0 | 0 | 0 | 321,632 (100) |
EM | 35,284 (75.23) | 11,411 (24.33) | 61 (0.13) | 0 | 144 (0.31) | 0 | 0 | 0 | 0 | 0 | 46,900 (100) |
ENZYME | 7,524 (87.17) | 1,093 (12.66) | 9 (0.10) | 0 | 5 (0.06) | 0 | 0 | 0 | 0 | 0 | 8,631 (100) |
IHC | 2,205,781 (68.67) | 966,307 (30.08) | 25,241 (0.79) | 351 (0.01) | 9,041 (0.28) | 5,481 (0.17) | 0 | 0 | 12 (<0.01) | 2 (<0.01) | 3,212,216 (100) |
CERVIX | 490,880 (41.36) | 449,685 (37.89) | 70,512 (5.94) | 592 (0.05) | 174,700 (14.72) | 0 | 0 | 3 (<0.01) | 503 (0.04) | 18 (<0.01) | 1,186,893 (100) |
BFC | 1,201,031 (46.50) | 1,053,678 (40.79) | 162,061 (6.27) | 2,248 (0.09) | 161,414 (6.25) | 2,319 (0.09) | 0 | 0 | 106 (<0.01) | 23 (<0.01) | 2,582,880 (100) |
AC | 219,121 (16.42) | 335,929 (25.17) | 152,361 (11.41) | 645 (0.05) | 626,573 (46.94) | 145 (0.01) | 1 (<0.01) | 0 | 32 (<0.01) | 29 (<0.01) | 1,334,836 (100) |
CB | 293,874 (54.58) | 196,885 (36.57) | 20,101 (3.73) | 124 (0.02) | 27,092 (5.03) | 369 (0.07) | 0 | 0 | 0 | 0 | 538,445 (100) |
HER2 | 8,605 (75.19) | 2,747 (24.00) | 86 (0.75) | 6 (0.05) | 1 (0.01) | 0 | 0 | 0 | 0 | 0 | 11,445 (100) |
MSI | 49,100 (85.29) | 8,318 (14.45) | 151 (0.26) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 57,569 (100) |
OUTSIDE | 276,885 (76.12) | 75,385 (20.73) | 1,391 (0.38) | 47 (0.01) | 9,667 (2.66) | 360 (0.10) | 0 | 0 | 0 | 1 (<0.01) | 363,736 (100) |
Summary | 10,954,750 (36.43) | 9,374,626 (31.18) | 3,068,803 (10.21) | 22,734 (0.08) | 6,590,723 (21.92) | 46,446 (0.15) | 1,284 (<0.01) | 3 (<0.01) | 5,619 (0.02) | 1,927 (0.01) | 30,066,915 (100) |
Administrative district | Biopsy | Non-maligGro | MaligGro LND | MaligGro LNDX | MAPPING | FS | BONE | SPECIAL | IF | EM |
---|---|---|---|---|---|---|---|---|---|---|
Etc. | 0 | 21 (<0.01) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seoul | 3,569,090 (30.24) | 2,487,048 (32.18) | 267,423 (46.34) | 113,181 (46.84) | 109,012 (50.46) | 317,546 (49.92) | 22,231 (27.33) | 830,214 (37.57) | 169,672 (46.92) | 26,715 (51.53) |
Busan | 1,007,783 (8.54) | 718,747 (9.30) | 57,598 (9.98) | 26,132 (10.81) | 18,263 (8.45) | 61,611 (9.69) | 9,156 (11.25) | 101,122 (4.58) | 39,230 (10.85) | 5,599 (10.80) |
Incheon | 701,281 (5.94) | 457,064 (5.91) | 42,029 (7.28) | 20,095 (8.32) | 12,743 (5.90) | 41,553 (6.53) | 5,388 (6.62) | 158,767 (7.18) | 18,329 (5.07) | 1,915 (3.69) |
Daegu | 914,814 (7.75) | 505,092 (6.54) | 43,935 (7.61) | 13,662 (5.65) | 9,264 (4.29) | 35,356 (5.56) | 10,090 (12.40) | 161,162 (7.29) | 22,793 (6.30) | 3,466 (6.68) |
Gwangju | 419,909 (3.56) | 314,418 (4.07) | 9,260 (1.60) | 2,575 (1.07) | 1,216 (0.56) | 7,133 (1.12) | 635 (0.78) | 31,555 (1.43) | 6,476 (1.79) | 1,167 (2.25) |
Daejeon | 435,340 (3.69) | 309,986 (4.01) | 19,421 (3.37) | 3,075 (1.27) | 3,934 (1.82) | 13,359 (2.10) | 6,968 (8.56) | 66,516 (3.01) | 12,276 (3.39) | 1,732 (3.34) |
Ulsan | 250,163 (2.12) | 168,514 (2.18) | 8,207 (1.42) | 4,827 (2.00) | 138 (0.06) | 8,178 (1.29) | 2,136 (2.63) | 41,843 (1.89) | 6,577 (1.82) | 698 (1.35) |
Gyeonggi-do | 1,978,367 (16.76) | 1,287,772 (16.66) | 67,488 (11.70) | 28,882 (11.95) | 37,470 (17.35) | 78,222 (12.30) | 11,599 (14.26) | 436,544 (19.75) | 49,950 (13.81) | 5,760 (11.11) |
Gangwon-do | 228,857 (1.94) | 150,249 (1.94) | 6,447 (1.12) | 3,586 (1.48) | 4,503 (2.08) | 10,730 (1.69) | 3,151 (3.87) | 67,670 (3.06) | 7,882 (2.18) | 758 (1.46) |
Chungcheongbuk-do | 250,413 (2.12) | 171,847 (2.22) | 5,083 (0.88) | 1,591 (0.66) | 590 (0.27) | 5,706 (0.90) | 1,927 (2.37) | 61,513 (2.78) | 2,266 (0.63) | 385 (0.74) |
Chungcheongnam-do | 313,423 (2.66) | 155,444 (2.01) | 5,393 (0.93) | 2,529 (1.05) | 3,700 (1.71) | 6,237 (0.98) | 177 (0.22) | 41,352 (1.87) | 6,644 (1.84) | 727 (1.40) |
Jeollabuk-do | 349,185 (2.96) | 192,196 (2.49) | 11,396 (1.97) | 7,030 (2.91) | 4,207 (1.95) | 14,340 (2.25) | 3,226 (3.97) | 20,504 (0.93) | 3,829 (1.06) | 458 (0.88) |
Jeollanam-do | 295,622 (2.50) | 177,955 (2.30) | 16,774 (2.91) | 7,613 (3.15) | 30 (0.01) | 11,400 (1.79) | 245 (0.30) | 35,185 (1.59) | 1,056 (0.29) | 200 (0.39) |
Gyeongsangbuk-do | 451,285 (3.82) | 220,085 (2.85) | 1,936 (0.34) | 816 (0.34) | 1,159 (0.54) | 1,852 (0.29) | 1,028 (1.26) | 44,136 (2.00) | 2,140 (0.59) | 270 (0.52) |
Gyeongsangnam-do | 532,322 (4.51) | 352,022 (4.55) | 12,136 (2.10) | 5,078 (2.10) | 8,698 (4.03) | 19,881 (3.13) | 2,205 (2.71) | 78,121 (3.54) | 9,437 (2.61) | 1,572 (3.03) |
Jeju | 100,466 (0.85) | 57,359 (0.74) | 2,538 (0.44) | 961 (0.40) | 1,094 (0.51) | 3,023 (0.48) | 1,194 (1.47) | 33,540 (1.52) | 3,070 (0.85) | 426 (0.82) |
Sejong-si | 4,372 (0.04) | 3,023 (0.04) | 0 | 0 | 0 | 0 | 0 | 104 (<0.01) | 0 | 0 |
Summary | 11,802,692 (100) | 7,728,842 (100) | 577,064 (100) | 241,633 (100) | 216,021 (100) | 636,127 (100) | 81,356 (100) | 2,209,848 (100) | 361,627 (100) | 51,848 (100) |
Administrative district | ENZYME | IHC | CERVIX | BFC | AC | CB | HER2 | MSI | OUTSIDE | Summary |
---|---|---|---|---|---|---|---|---|---|---|
Etc. | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 21 (<0.01) |
Seoul | 6,622 (71.09) | 1,767,200 (46.85) | 543,513 (40.40) | 1,146,492 (39.19) | 338,246 (22.66) | 273,523 (44.02) | 6,944 (52.83) | 36,679 (55.68) | 261,862 (61.69) | 12,293,213 (35.55) |
Busan | 521 (5.59) | 309,799 (8.21) | 106,119 (7.89) | 307,125 (10.50) | 184,239 (12.34) | 42,686 (6.87) | 898 (6.83) | 6,723 (10.21) | 24,460 (5.76) | 3,027,811 (8.76) |
Incheon | 144 (1.55) | 234,731 (6.22) | 86,153 (6.40) | 235,529 (8.05) | 92,453 (6.19) | 38,392 (6.18) | 1,297 (9.87) | 4,462 (6.77) | 19,867 (4.68) | 2,172,192 (6.28) |
Daegu | 501 (5.38) | 402,725 (10.68) | 88,991 (6.62) | 131,159 (4.48) | 150,027 (10.05) | 64,550 (10.39) | 815 (6.20) | 3,096 (4.70) | 22,940 (5.40) | 2,584,438 (7.47) |
Gwangju | 136 (1.46) | 36,164 (0.96) | 38,359 (2.85) | 74,981 (2.56) | 133,266 (8.93) | 4,443 (0.72) | 27 (0.21) | 0 | 1,441 (0.34) | 1,083,161 (3.13) |
Daejeon | 53 (0.57) | 71,899 (1.91) | 40,038 (2.98) | 83,455 (2.85) | 45,632 (3.06) | 7,065 (1.14) | 194 (1.48) | 36 (0.05) | 9,240 (2.18) | 1,130,219 (3.27) |
Ulsan | 4 (0.04) | 46,112 (1.22) | 18,427 (1.37) | 53,310 (1.82) | 30,219 (2.02) | 8,665 (1.39) | 153 (1.16) | 2 (<0.01) | 3,367 (0.79) | 651,540 (1.88) |
Gyeonggi-do | 849 (9.11) | 569,103 (15.09) | 219,328 (16.30) | 374,113 (12.79) | 221,132 (14.81) | 92,707 (14.92) | 1,820 (13.85) | 10,526 (15.98) | 58,704 (13.83) | 5,530,336 (15.99) |
Gangwon-do | 24 (0.26) | 63,272 (1.68) | 35,913 (2.67) | 69,897 (2.39) | 15,218 (1.02) | 17,189 (2.77) | 208 (1.58) | 624 (0.95) | 1,517 (0.36) | 687,695 (1.99) |
Chungcheongbuk-do | 0 | 13,816 (0.37) | 11,057 (0.82) | 45,783 (1.56) | 30,046 (2.01) | 8,844 (1.42) | 55 (0.42) | 371 (0.56) | 2,802 (0.66) | 614,095 (1.78) |
Chungcheongnam-do | 6 (0.06) | 26,956 (0.71) | 29,260 (2.18) | 56,711 (1.94) | 23,501 (1.57) | 17,295 (2.78) | 167 (1.27) | 0 | 2,420 (0.57) | 691,942 (2.00) |
Jeollabuk-do | 8 (0.09) | 71,973 (1.91) | 28,958 (2.15) | 93,002 (3.18) | 54,035 (3.62) | 2,377 (0.38) | 150 (1.14) | 259 (0.39) | 3,424 (0.81) | 860,557 (2.49) |
Jeollanam-do | 3 (0.03) | 55,684 (1.48) | 27,585 (2.05) | 55,997 (1.91) | 68,206 (4.57) | 5,211 (0.84) | 285 (2.17) | 798 (1.21) | 6,128 (1.44) | 765,977 (2.22) |
Gyeongsangbuk-do | 10 (0.11) | 8,784 (0.23) | 26,061 (1.94) | 58,344 (1.99) | 41,342 (2.77) | 6,361 (1.02) | 7 (0.05) | 1 (<0.01) | 330 (0.08) | 865,947 (2.50) |
Gyeongsangnam-do | 339 (3.64) | 70,854 (1.88) | 30,645 (2.28) | 109,302 (3.74) | 54,687 (3.66) | 29,855 (4.80) | 92 (0.70) | 2,266 (3.44) | 5,066 (1.19) | 1,324,578 (3.83) |
Jeju | 95 (1.02) | 22,901 (0.61) | 14,340 (1.07) | 30,246 (1.03) | 10,421 (0.70) | 2,217 (0.36) | 33 (0.25) | 36 (0.05) | 933 (0.22) | 284,893 (0.82) |
Sejong-si | 0 | 5 (<0.01) | 484 (0.04) | 129 (<0.01) | 331 (0.02) | 12 (<0.01) | 0 | 0 | 2 (<0.01) | 8,462 (0.02) |
Summary | 9,315 (100) | 3,771,978 (100) | 1,345,231 (100) | 2,925,575 (100) | 1,493,001 (100) | 621,392 (100) | 13,145 (100) | 65,879 (100) | 424,503 (100) | 34,577,077 (100) |
Pathologic examination | Performed in their own hospitals | Performed using outside services | Convalescent hospital | Etc. | Summary |
---|---|---|---|---|---|
Biopsy | 4,484,330 (43.53) | 5,784,009 (56.15) | 28,542 (0.28) | 4,012 (0.04) | 10,300,893 (100) |
Non-maligGro | 3,621,714 (53.91) | 3,034,515 (45.17) | 61,635 (0.92) | 533 (0.01) | 6,718,397 (100) |
MaligGro LND | 475,825 (95.16) | 20,673 (4.13) | 3,512 (0.70) | 2 (<0.01) | 500,012 (100) |
MaligGro LNDX | 206,618 (98.07) | 3,252 (1.54) | 821 (0.39) | 2 (<0.01) | 210,693 (100) |
MAPPING | 185,267 (98.79) | 1,123 (0.60) | 1,152 (0.61) | 3 (<0.01) | 187,545 (100) |
FS | 545,200 (98.75) | 4,089 (0.74) | 2,806 (0.51) | 7 (<0.01) | 552,102 (100) |
BONE | 58,330 (78.39) | 13,576 (18.25) | 2,496 (3.35) | 4 (0.01) | 74,406 (100) |
SPECIAL | 1,487,782 (80.09) | 363,521 (19.57) | 5,793 (0.31) | 588 (0.03) | 1,857,684 (100) |
IF | 259,628 (80.72) | 58,684 (18.25) | 3,317 (1.03) | 3 (<0.01) | 321,632 (100) |
EM | 31,593 (67.36) | 15,175 (32.36) | 132 (0.28) | 0 | 46,900 (100) |
ENZYME | 7,779 (90.13) | 787 (9.12) | 65 (0.75) | 0 | 8,631 (100) |
IHC | 3,129,765 (97.43) | 62,839 (1.96) | 19,503 (0.61) | 109 (<0.01) | 3,212,216 (100) |
CERVIX | 901,312 (75.94) | 278,397 (23.46) | 1,057 (0.09) | 6,127 (0.52) | 1,186,893 (100) |
BFC | 2,068,613 (80.09) | 490,820 (19.00) | 22,888 (0.89) | 559 (0.02) | 2,582,880 (100) |
AC | 458,090 (34.32) | 855,980 (64.13) | 489 (0.04) | 20,277 (1.52) | 1,334,836 (100) |
CB | 505,034 (93.79) | 29,688 (5.51) | 3,073 (0.57) | 650 (0.12) | 538,445 (100) |
HER2 | 9,856 (86.12) | 1,587 (13.87) | 2 (0.02) | 0 | 11,445 (100) |
MSI | 35,244 (61.22) | 22,325 (38.78) | 0 | 0 | 57,569 (100) |
OUTSIDE | 356,892 (98.12) | 6,640 (1.83) | 165 (0.05) | 39 (0.01) | 363,736 (100) |
Summary | 18,828,872 (62.62) | 11,047,680 (36.74) | 157,448 (0.52) | 32,915 (0.11) | 30,066,915 (100) |
Non-maligGro, resected specimen requiring gross sectioning; NPB, number of paraffin blocks; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; HR, examination of hormone receptor in tissue; CERVIX, cervicovaginal cytopathology; L-, liquid based; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2 (FISH),
Values are presented as number (%). Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2,
Values are presented as number (%). Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy
Values are presented as number (%). ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2,
Values are presented as number (%). Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2,
Values are presented as number (%). Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy.
Values are presented as number (%). ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2,
Values are presented as number (%). Non-maligGro, resected specimen requiring gross sectioning; MaligGro, resected specimen for malignant tumor requiring gross sectioning; LND, with lymph node dissection; LNDX, without lymph node dissection; MAPPING, histologic mapping of tumor; FS, emergency histopathologic examination during surgery; BONE, histopathologic examination for bone; SPECIAL, special stain examinations; IF, tissue immunofluorescent microscopic examination; EM, tissue electron microscopy; ENZYME, enzyme histochemistry; IHC, immunohisto(cyto)chemistry; CERVIX, cervicovaginal cytopathology; BFC, body fluid cytopathology; AC, aspiration cytopathology; CB, cell block; HER2,