Total protein, paper electrophoretic patterns, CRP reaction and hemoglobin in lepromatous leprosy cases were tested to estimate recent evaluations compare to past reports. 1. Total protein was 6.99±0.53 gm% in mean value and this result was similar to past reports. 2. In findings of the electrophoretic patterns albumin and α1-, α2-, β-, and γ-globulin were 47.38±0.86%, 6.48±0.94%, 9.54±0.38%, 13.13 ±0.54% and 23.38±0.65% of total protein. From this result of protein fractions, it showed decreased albumin and increased globulin fractions which resulted in decrease of A/G ratio and this result is nearly as same as past reports. 3. There were only 4 cases (8.33%) of positive CRP reaction. 4. The mean value of hemoglobin content was 12.43±0. l7gm%.