Forty five cases consisting of 42 cases of VDRL positive sera and 3 cases of VDRL negative sera were compared to TPHA test. Thirty four cases (81.0%) of 42 positive VDRL sera were TPHA positive and consider -ed to be syphilis. Eight cases (19.0%) of 42 positive VDRL were TPHA negative and considered to be non-syphitic. However one case of 8 negative TPHA was exception. This case was syphilis on the diagnosis and was receiving antisyphilis therapy showing remarkable lowering of serologic titer in VDRL. Three cases of negative VDRL showed also negative TPHA. The agreement between VDRL and TPHA was 91.8% .