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Histopathologic Study of 2 Separate Dysplastic Lesions in one Stomach and its Malignant Change -Papillary adenoma and Atypical epithelial lesion-
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Etc Histopathologic Study of 2 Separate Dysplastic Lesions in one Stomach and its Malignant Change -Papillary adenoma and Atypical epithelial lesion-
Journal of Pathology and Translational Medicine 1978;12(4):375-381
DOI: https://doi.org/
Department of Pathology, National Medical Center
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A subtotally removed stomach of a 47 year old male patient which has two separate protruded lesions, papillary adenoma and atypical epithelial lesion, was examined with histotopographic reconstruction method. Both lesions were associated similarly with diffuse dysplastic epithelial changes, and the former, papillary adenoma, demonstrated focal malignant change with submucosal invasion. Dysplasia or cellular atypism accompanied by the papillary adenoma or atypical epithelial lesions (often called as borderline lesion, tubular adenorna, or adenomatous polyp) has the evidence of malignant potential and must be carefully examined for coexisting carcinoma or indepencent carcinoma in neighboring gastric mucosa. A more radical surgical approach than other benign gastric polyps is required for these lesions.

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