Abstract

Nephrogenic adenoma is a papillary or polypoid bladder lesion of uncertain pathogenesis, which may easily be mistaken for carcinoma of the bladder on cystocsopy. Microscopically, it consists of numerous epithelial tubules lined by simple cuboidal epithelium, some of which usually shows cystic change containing proteinaceous material in the lamina propria. It is widely accepted that nephrogenic adenoma may be metaplastic process of urothelium rather than true neoplastic process as shown by usual concurrence with chronic inflammatory condition. We have experienced a case of nephrogenic adenoma of urinary bladder in a 24 year old man suffering from pulmonary and renal tuberculosis. The natural history, pathogenesis and managements of patients with nephrogenic adenoma are discussed.