Abstract

The incidence of leiomyosarcoma of the small intestine was low, variable reported 1 to 3 per cent of all neoplasms of the gastrointestinal tracts and 10 to 14 per cent of all cancers of the small intestine. We have recently experienced two cases of leiomyosarcoma, one of which is located in the ileum from 63-year old female and the other in the jejunum from 53-year old female. Grossly, the two tumor masses measured 7×6×5㎝ and 10×10×8㎝ in dimensions, respectively. There were areas of mucosal ulceration and hemorrhage over the mucosa. The cut surface of the masses was relatively well-demarcated, grayish white fibrous tissue with a few hemorrhagic necrosis throughout the whole layers except for mucosa. Metastasis was found in the retroperitoneum in one case and the liver in the other. Microscopically, both tumors were composed of interlacing bundles of smooth muscle cells having increased cellularity and atypical features. More than 6 mitoses per ten high power fields were found in both tumors. The metastatic lesions were infiltrated with above neoplastic cells. A brief review of literatures was made.