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A Malignant Schwannoma in von Recklinghausen's Disease
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HOME > J Pathol Transl Med > Volume 17(4); 1983 > Article
Etc A Malignant Schwannoma in von Recklinghausen's Disease
Journal of Pathology and Translational Medicine 1983;17(4):477-480
DOI: https://doi.org/
Department of Pathology, College of Medicine, Chungnam National University
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A case of malignant schwannoma arising from the brachial plexus in von Recklinghausen's disease was present. Because of its difficult microscopic recognition, the diagnosis of malignant schwannoma should be the primary consideration in only two following circumstances: 1) when the tumor develops in a patient with von Recklinghausen's disease and 2) when the tumor is obviously arising within the anatomic compartment of major nerve or in continuity with an unquestionable neurofibroma. The authors experienced a malignant schwannoma in a 23-year-old male patient with von Recklinghausen's disease. The tumor, measuring 17×8×8㎝ in dimension and 500gm in weight, was arising in continuity with the brachial plexus. Microscopically it consisted of relatively monomorphic spindle cells with frequent mitoses. A discussion on the histogenesis and the clinicopathologic characteristics, with a brief literature review, were described.

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