| Home | E-Submission | Sitemap | Contact Us
JPTM > Volume 44(4); 2010 > Article
The Korean Journal of Pathology 2010;44(4): 435-440.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.4.435
First Report of a Gangliocytic Paraganglioma Arising in a Tailgut Cyst.
Yosep Chong, Mee Yon Cho
Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea. meeyon@yonsei.ac.kr
Here we present the first report of a gangliocytic paraganglioma arising in a tailgut cyst; it occurred in a 56-year-old man. Tailgut cysts are uncommon congenital hamartomatous lesions that arise in the retrorectal presacral space in infants or adults. Benign or malignant tumors associated with tailgut cysts are rarely described; the most common tumors are adenocarcinomas and carcinoid tumors. A gangliocytic paraganglioma is a rare benign tumor that occurs nearly exclusively in the second portion of the duodenum. Rare cases have been reported at other locations, but a tailgut cyst has never been described. In our case, a resected 3.9 x 3.3 x 3 cm mass was composed predominantly of a solid yellow white neuroendocrine tumor within the area of a tailgut cyst. The neuroendocrine component of this tumor was different from previously described carcinoid tumors with respect to the histologic findings of neural differentiation as well as the intermixed typical gangliocytic features highlighted by immunohistochemical stains for S-100 protein and neurofilament. Although an intermixed area of the tailgut cyst and gangliocytic paraganglioma were found in some areas, the pathogenesis of this tumor remains to be elucidated.
Key Words: Hamartoma; Cyst; Paraganglioma
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
Supplement  Supplement
Related articles
A Rare Case of Thymic Gangliocytic Paraganglioma  2016 March;50(2)
Case Report of Meconium Peritonitis Arising in Twin  1971 December;5(2)
Adenocarcinoma Arising in Gastric Duplication Cyst  2014 April;48(2)
Gangliocytic Paraganglioma.  2005 December;39(6)