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The Korean Journal of Cytopathology 2007;18(1): 81-86.
Imprint Cytology of a Desmoplastic Small Round Cell Tumor: A Case Report.
Joon Hyuk Choi, Yong Jin Kim, Jae Hwang Kim
1Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea. joonhyukchoi@yumail.ac.kr
2Department of Sugery, Yeungnam University College of Medicine, Daegu, Korea.
ABSTRACT
Desmoplastic small round cell tumor (DSRCT) is a rare malignant mesenchymal neoplasm. It mainly involves the abdominal or pelvic peritoneum of male adolescents. We report here the imprint cytologic features of a case of DSRCT occurring in the intraabdominal cavity of a 21-year-old man. A microscopic examination showed moderate cellularity. The tumor cells were singly arranged and arranged in clusters. The cells had round to oval nuclei with finely granular chromatin, inconspicuous nucleoli and scanty cytoplasm. Some tumor cells showed nuclear molding, and some cells had an epitheloid appearance with a large amount of lightly eosinophilic cytoplasm. A rosette-like pattern was present. Spindle-shaped, fibroblastic stromal cells were occasionally found. The tumor cells were immunoreactive for the markers cytokeratin (AE1/AE3), epithelial membrane antigen (EMA), desmin, vimentin and neuron specific enolase (NSE).
Key Words: Desmoplastic small round cell tumor; Intraabdominal; Cytology; Imprint