Abstract

The sex cord tumor with annular tubules is a rare ovarian neoplasm the predominant component of which has morphologic features intermediate between those of the granulosa cell tumor and those of the Sertoli cell tumor; focal differentiation into either granulosa cell or Sertoli cell tumor may occur. It is microscopically characterized by the formation of simple and complex annular tubules with hyaline bodies and it occurs often in patients with Peutz-Jeghers syndrome. Recently author experienced a case of ovarian sex cord tumor with annular tubules in a 49 year old female without Peutz-Jeghers syndrome. Clinical data and histopathological findings of the case were discussed and a brief review of the literature on this entity, especially the relationship to Peutz-Jeghers syndrome and the pathological differences between the tumor associated with and without Peutz-Jeghers syndrome.