Skip Navigation
Skip to contents

JPTM : Journal of Pathology and Translational Medicine


Author index

Page Path
HOME > Articles and issues > Author index
Soon Jae Kim 1 Article
Comparison of Liqui-PREP(TM) and Conventional Preparations in Thyroid Fine Needle Aspiration.
Eun Su Park, Eun Yoon Cho, In Gu Do, Soon Jae Kim, Jung Hee Shin, Boo Kyung Han, Young Lyun Oh
Korean J Pathol. 2009;43(6):550-556.
  • 3,803 View
  • 22 Download
  • 3 Citations
AbstractAbstract PDF
Liqui-PREP(TM) (LP) is a new liquid-based cytologic preparation that produces a thin layer of cells.
Thyroid aspirates were obtained from 189 patients and divided to prepare pairs of conventional preparation (CP) and LP slides. The CP slides were routinely diagnosed by attending staffs and classified into the six categories. LP slides were independently evaluated by three cytopathologists and classified in an identical manner. Agreements between CP and LP diagnoses were investigated and interobserver variability of thyroid aspiration cytology results obtained using the LP method was determined using kappa values. RESULTS: CP and LP slides from 155 patients (83%) were identically classified by all of three cytopathologists. Concurrences between CP and LP diagnoses for the three cytopathologists were 89% (kappa=0.78), 92% (kappa=0.87), and 85% (kappa=0.70), respectively. Interobserver agreement among the three cytopathologists for LP slides ranged from substantial to almost perfect (kappa=0.84, 0.74 and 0.84). However, a lack of interobserver agreement was found for LP slides of the undetermined category as determined by original CP-based diagnoses. Moreover, cytomorphological alterations in the benign category appeared more worrisome for LP slides.
An awareness of the novel cytomorphologic changes induced by the LP method is needed to avoid misinterpretations.


Citations to this article as recorded by  
  • Liquid base cytology in evaluation of thyroid nodules
    Elahe Keyhani, Sasan A Sharghi, Rana Amini, Sina A Sharghi, Masoud Karimlou, Fatemeh A Moghaddam, Bagher Larijani
    Journal of Diabetes & Metabolic Disorders.2014;[Epub]     CrossRef
  • Diagnostic value of liquid-based (Liqui-PREP) preparations and interobserver reproducibility in fine needle aspiration cytology of the nodular thyroid lesions
    U. S. Tetikkurt, F. Oz Puyan, F. Oz, N. Erdogan, S. Ceylan, A. Yakupoglu
    Diagnostic Cytopathology.2012; 40(5): 388.     CrossRef
  • Application of Bethesda System for Reporting Thyroid Aspiration Cytology
    Kyungji Lee, Chan-Kwon Jung, Kyo-Young Lee, Ja-Seong Bae, Dong-Jun Lim, So-Lyung Jung
    The Korean Journal of Pathology.2010; 44(5): 521.     CrossRef

JPTM : Journal of Pathology and Translational Medicine