- Squamous Cell Carcinoma of the Seminal Vesicle from Zinner Syndrome: A Case Report and Review of Literature
-
Younghoon Kim, Hae Woon Baek, Eunoh Choi, Kyung Chul Moon
-
J Pathol Transl Med. 2015;49(1):85-88. Published online January 15, 2015
-
DOI: https://doi.org/10.4132/jptm.2014.10.28
-
-
9,538
View
-
67
Download
-
6
Citations
-
PDF
-
Citations
Citations to this article as recorded by 
- Zinner syndrome: a rare diagnosis in infancy
Joanne Michelle Oida Rose, Ravi Banthia, Zain Tamboli, Hira Lal BMJ Case Reports.2022; 15(5): e248558. CrossRef - Classifying seminal vesicle cysts in the diagnosis and treatment of Zinner syndrome: A report of six cases and review of available literature
Zhengwu Tan, Bing Li, Lan Zhang, Ping Han, Haitao Huang, Andrew Taylor, Xin Li Andrologia.2020;[Epub] CrossRef - Incidental imaging findings suggesting Zinner syndrome in a young patient with pulmonary embolism: A case report
Benedikt Hergan, Franz A. Fellner, Kaveh Akbari Radiology Case Reports.2020; 15(4): 437. CrossRef - Ectopic ureter associated with Zinner’s syndrome in a kidney recipient: case report and literature review
Korhan Tuncer, Gizem Kilinc, Ismail Sert, Goksever Akpinar, Cem Tugmen Revista da Associação Médica Brasileira.2020; 66(5): 692. CrossRef - Zinner’s Syndrome: A Rare Diagnosis of Dysuria Based on Imaging
Ahmed Ibrahimi, Abdelmoughit Hosni, Idriss Ziani, Fatima Zahra Laamrani, Hachem El Sayegh, Laila Jroundi, Lounis Benslimane, Yassine Nouini, Apul Goel Case Reports in Urology.2020; 2020: 1. CrossRef - Primary squamous cell carcinoma of the seminal vesicle
Lu Fang, Qian Hong, Lei Chen, Yi Wang, Liang-Kuan Bi, Dong-Dong Xie, De-Xin Yu Medicine.2019; 98(12): e14788. CrossRef
- Diagnostic Accuracy of Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology of Pancreatic Lesions
-
Hae Woon Baek, Min Jee Park, Ye-Young Rhee, Kyoung Bun Lee, Min A Kim, In Ae Park
-
J Pathol Transl Med. 2015;49(1):52-60. Published online January 15, 2015
-
DOI: https://doi.org/10.4132/jptm.2014.10.26
-
-
8,294
View
-
72
Download
-
26
Citations
-
Abstract
PDF
- Background
Endoscopic ultrasound–guided fine needle aspiration cytology (EUS-FNAC) is currently the most commonly used procedure for obtaining cytologic specimens of the pancreas. It is accurate, minimally invasive, safe and cost-effective. However, there is discrepancy between cytological and surgical diagnoses. This study was aimed at evaluating the diagnostic accuracy of EUS-FNAC of the pancreas. Methods: We performed a retrospective review of 191 cases of pancreatic lesions initially diagnosed by EUS-FNAC with subsequent histological diagnosis between 2010 and 2012 in the Department of Pathology, Seoul National University Hospital. Cytologic and surgical diagnoses were categorized into five groups: negative, benign, atypical, malignant, and insufficient for diagnosis. Subsequently, 167 cases with satisfactory yield in both surgical and cytology specimens were statistically analyzed to determine correlations with diagnosis. Results: In comparison to surgical diagnoses, cytologic diagnoses were true-positive in 103 cases (61.7%), true-negative in 28 cases (16.8%), false-positive in 9 cases (5.4%), and false-negative in 27 cases (16.1%). The diagnostic accuracy was 78.4%, sensitivity was 79.2%, and specificity was 75.7%. The positive predictive value was 92.0%, and negative predictive value was 50.9%. Conclusions: EUS-FNAC has high accuracy, sensitivity, specificity and positive predictive value. Overcoming the limitations of EUS-FNAC will make it a useful and reliable diagnostic tool for accurate evaluation of pancreatic lesions.
-
Citations
Citations to this article as recorded by 
- Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study
Shivaraj Afzalpurkar, Vijay Kumar Rai, Nikhil Sonthalia, Gajanan Rodge, Awanesh Tewary, Mahesh Goenka Journal of Digestive Endoscopy.2023;[Epub] CrossRef - The impact of preoperative EUS-FNA for distal resectable pancreatic cancer: Is it really effective enough to take risks?
Jin-Seok Park, Jae Hoon Lee, Tae Jun Song, Joune Seup Lee, Seok Jung Jo, Dong Wook Oh, Ki Byung Song, Dae Wook Hwang, Do Hyun Park, Sang Soo Lee, Song Cheol Kim, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim Surgical Endoscopy.2022; 36(5): 3192. CrossRef - Magnetic Resonance Imaging Radiomics‐Based Nomogram From Primary Tumor for Pretreatment Prediction of Peripancreatic Lymph Node Metastasis in Pancreatic Ductal Adenocarcinoma: A Multicenter Study
Zhenshan Shi, Chengle Ma, Xinming Huang, Dairong Cao Journal of Magnetic Resonance Imaging.2022; 55(3): 823. CrossRef - Role of Pathologist in the Era of Image-Guided and EUS-Guided Aspirations: A 10-Year Study at a Single Tertiary Care Oncology Institute in North India
Gurudutt Gupta, Anila Sharma, Meenakshi Kamboj, Anurag Sharma, Sunil Pasricha, Garima Durga, Anurag Mehta, Avinash Rao Acta Cytologica.2022; 66(3): 187. CrossRef - Predicting Factors for Pancreatic Malignancy with Computed Tomography and Endoscopic Ultrasonography in Chronic Pancreatitis
Jian-Han Lai, Keng-Han Lee, Chen-Wang Chang, Ming-Jen Chen, Ching-Chung Lin Diagnostics.2022; 12(4): 1004. CrossRef - Phenotypic profiling of pancreatic ductal adenocarcinoma plasma-derived small extracellular vesicles for cancer diagnosis and cancer stage prediction: a proof-of-concept study
Wei Zhang, Ling Wang, Dan Li, Douglas H. Campbell, Bradley J. Walsh, Nicolle H. Packer, Qing Dong, Erkang Wang, Yuling Wang Analytical Methods.2022; 14(23): 2255. CrossRef - Cancer-derived small extracellular vesicles: emerging biomarkers and therapies for pancreatic ductal adenocarcinoma diagnosis/prognosis and treatment
Wei Zhang, Douglas H. Campbell, Bradley J. Walsh, Nicolle H. Packer, Dingbin Liu, Yuling Wang Journal of Nanobiotechnology.2022;[Epub] CrossRef - Single Cell RNA Sequencing: A New Frontier in Pancreatic Ductal Adenocarcinoma
Maroun Bou Zerdan, Malek Shatila, Dhruv Sarwal, Youssef Bouferraa, Morgan Bou Zerdan, Sabine Allam, Merima Ramovic, Stephen Graziano Cancers.2022; 14(19): 4589. CrossRef - Molecular Subtyping and Precision Medicine for Pancreatic Cancer
Fieke Froeling, Raffaella Casolino, Antonio Pea, Andrew Biankin, David Chang Journal of Clinical Medicine.2021; 10(1): 149. CrossRef - Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine
R. Casolino, C. Braconi, G. Malleo, S. Paiella, C. Bassi, M. Milella, S.B. Dreyer, F.E.M. Froeling, D.K. Chang, A.V. Biankin, T. Golan Annals of Oncology.2021; 32(2): 183. CrossRef - Diagnostic value of various liquid biopsy methods for pancreatic cancer
Yuzhou Zhu, Hao Zhang, Nan Chen, Jianqi Hao, Hongyu Jin, Xuelei Ma Medicine.2020; 99(3): e18581. CrossRef - Factors affecting cytological results of endoscopic ultrasound guided-fine needle aspiration during learning
Jian-Han Lai, Hsiang-Hung Lin, Ching-Chung Lin Diagnostic Pathology.2020;[Epub] CrossRef - Comparison between Conventional Smear and Liquid-Based Preparation in Endoscopic Ultrasonography-Fine Needle Aspiration Cytology of Pancreatic Lesions
Soo Hee Ko, Jung-Soo Pyo, Byoung Kwan Son, Hyo Young Lee, Il Whan Oh, Kwang Hyun Chung Diagnostics.2020; 10(5): 293. CrossRef - Evaluation of Pancreatic Lesions With Endoscopic Ultrasound and Fine Needle Aspiration
Yan Luk, Wong Hoi She, Felix Che Lok Chow, Ka Wing Ma, Simon Hing Yin Tsang, Wing Chiu Dai, Tan To Cheung, Chung Mau Lo Surgical Innovation.2020; 27(5): 431. CrossRef - The applicability of Papanicolaou Society of Cytopathology system on reporting endoscopic ultrasound‐guided fine needle aspiration cytology specimens of pancreatic lesions in situations with limited availability of ancillary tests. Experience at a single
Mrinmay Kumar Mallik, Laila Rafiq Qadan, Abdullah Al Naseer, Ali AlAli, Taiba Al Ansari, Shafi Ahmed Inamdar Naquib, Dilip Kumar Das, Kusum Kapila Cytopathology.2020; 31(6): 564. CrossRef - Circulating Cell-Free DNA-Based Liquid Biopsy Markers for the Non-Invasive Prognosis and Monitoring of Metastatic Pancreatic Cancer
Marta Toledano-Fonseca, M. Teresa Cano, Elizabeth Inga, Rosa Rodríguez-Alonso, M. Auxiliadora Gómez-España, Silvia Guil-Luna, Rafael Mena-Osuna, Juan R. de la Haba-Rodríguez, Antonio Rodríguez-Ariza, Enrique Aranda Cancers.2020; 12(7): 1754. CrossRef - Risk of malignancy in the categories of the Papanicolaou Society of Cytopathology system for reporting pancreaticobiliary cytology
Raza S. Hoda, Elizabeth B. Finer, Ronald N. Arpin, Matthew Rosenbaum, Martha B. Pitman Journal of the American Society of Cytopathology.2019; 8(3): 120. CrossRef - Endoscopic ultrasound guided fine‐needle aspiration vs core needle biopsy for solid pancreatic lesions: Comparison of diagnostic accuracy and procedural efficiency
Aslam Syed, Olivia Babich, Bharat Rao, Shailendra Singh, Neil Carleton, Abhishek Gulati, Archana Kulkarni, Mrinal Garg, Katie Farah, Gursimran Kochhar, Suzanne Morrissey, Marcia Mitre, Abhijit Kulkarni, Manish Dhawan, Jan F. Silverman, Majed Pharaon, Shya Diagnostic Cytopathology.2019; 47(11): 1138. CrossRef - Liquid Biopsy as Surrogate for Tissue for Molecular Profiling in Pancreatic Cancer: A Meta-Analysis Towards Precision Medicine
Claudio Luchini, Nicola Veronese, Alessia Nottegar, Vera Cappelletti, Maria G. Daidone, Lee Smith, Christopher Parris, Lodewijk A. A. Brosens, Maria G. Caruso, Liang Cheng, Christopher L. Wolfgang, Laura D. Wood, Michele Milella, Roberto Salvia, Aldo Scar Cancers.2019; 11(8): 1152. CrossRef - It is necessary to exam bottom and top slide smears of EUS-FNA for pancreatic cancer
Jong-chan Lee, Haeryoung Kim, Hyoung Woo Kim, Jongchan Lee, Kyu-hyun Paik, Jingu Kang, Jin-Hyeok Hwang, Jaihwan Kim Hepatobiliary & Pancreatic Diseases International.2018; 17(6): 553. CrossRef - Preoperative EUS-guided FNA: effects on peritoneal recurrence and survival in patients with pancreatic cancer
Sun Hwa Kim, Young Sik Woo, Kwang Hyuck Lee, Jong Kyun Lee, Kyu Taek Lee, Joo Kyung Park, Soo Hoon Kang, Ji Won Kim, Jae Keun Park, Sung-Wook Park Gastrointestinal Endoscopy.2018; 88(6): 926. CrossRef - Cytological characteristics of atypical cells in endoscopic ultrasound-guided fine-needle aspiration specimens obtained from the pancreas
Shikine ESAKA, Yoko MATSUDA, Yuri HAMASHIMA, Masayuki IMAIZUMI, Hiroya KOJIMA, Yuri KISO, Hiroto SHIRAHATA, Mayumi KINOSHITA, Akemi SUZUKI, Tomio ARAI The Journal of the Japanese Society of Clinical Cytology.2018; 57(4): 199. CrossRef - Performance measures for endoscopic retrograde cholangiopancreatography and endoscopic ultrasound: A European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Dirk Domagk, Kofi W Oppong, Lars Aabakken, Laszlo Czakó, Tibor Gyökeres, Gianpiero Manes, Peter Meier, Jan-Werner Poley, Thierry Ponchon, Andrea Tringali, Cristina Bellisario, Silvia Minozzi, Carlo Senore, Cathy Bennett, Michael Bretthauer, Cesare Hassan, United European Gastroenterology Journal.2018; 6(10): 1448. CrossRef - Performance measures for ERCP and endoscopic ultrasound: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Dirk Domagk, Kofi W. Oppong, Lars Aabakken, Laszlo Czakó, Tibor Gyökeres, Gianpiero Manes, Peter Meier, Jan-Werner Poley, Thierry Ponchon, Andrea Tringali, Cristina Bellisario, Silvia Minozzi, Carlo Senore, Cathy Bennett, Michael Bretthauer, Cesare Hassan Endoscopy.2018; 50(11): 1116. CrossRef - Imaging modalities for characterising focal pancreatic lesions
Lawrence MJ Best, Vishal Rawji, Stephen P Pereira, Brian R Davidson, Kurinchi Selvan Gurusamy Cochrane Database of Systematic Reviews.2017;[Epub] CrossRef - Percutaneous ultrasound-guided core needle biopsy of solid pancreatic masses: Results in 250 patients
Guven Kahriman, Nevzat Ozcan, Serap Dogan, Soner Ozmen, Kemal Deniz Journal of Clinical Ultrasound.2016; 44(8): 470. CrossRef
- Transglutaminase 2 Expression and Its Prognostic Significance in Clear Cell Renal Cell Carcinoma
-
Min Jee Park, Hae Woon Baek, Ye-Young Rhee, Cheol Lee, Jeong Whan Park, Hwal Woong Kim, Kyung Chul Moon
-
J Pathol Transl Med. 2015;49(1):37-43. Published online January 15, 2015
-
DOI: https://doi.org/10.4132/jptm.2014.10.25
-
-
8,036
View
-
64
Download
-
13
Citations
-
Abstract
PDF
- Background
A few recent studies have demonstrated a possible role of transglutaminase 2 (TG2) in tumorigenesis or progression of renal cell carcinoma (RCC). The aim of this study was to examine TG2 expression and its clinicopathologic significance in a large number of human clear cell RCCs (CCRCCs). Methods: We analyzed 638 CCRCC patients who underwent partial or radical nephrectomy between 1995 and 2005. The expression of TG2 was determined by immunohistochemistry and categorized into four groups, according to staining intensity: negative (0), mild (1+), moderate (2+), and strong (3+). Results: TG2 staining intensity was negative in 8.5% of CCRCC (n=54), 1+ in 32.6% (n=208), 2+ in 50.5% (n=322), and 3+ in 8.5% (n=54). Strong TG2 expression was correlated with high Fuhrman nuclear grade (p=.011), high T category (p=.049), metastasis (p=.043) and male sex (p<.001) but not with N category.The survival analysis showed a significant association between strong TG2 expression and worse overall and cancer-specific survival (p=.027 and p=.010, respectively). On multivariate analysis, strong TG2 expression was a marginally significant prognostic indicator for Fuhrman nuclear grade and TNM staging (p=.054). Conclusions: Our study is the first to demonstrate the clinicopathologic significance of TG2 expression in a large number of human CCRCC samples. Strong TG2 expression was associated with high nuclear grade and poor prognosis.
-
Citations
Citations to this article as recorded by 
- Application of a Fluorescence Anisotropy-Based Assay to Quantify Transglutaminase 2 Activity in Cell Lysates
Sandra Hauser, Paul Sommerfeld, Johanna Wodtke, Christoph Hauser, Paul Schlitterlau, Jens Pietzsch, Reik Löser, Markus Pietsch, Robert Wodtke International Journal of Molecular Sciences.2022; 23(9): 4475. CrossRef - The Biological and Biomechanical Role of Transglutaminase-2 in the Tumour Microenvironment
Robert Tempest, Sonia Guarnerio, Rawan Maani, Jamie Cooper, Nicholas Peake Cancers.2021; 13(11): 2788. CrossRef - A Precision Strategy to Cure Renal Cell Carcinoma by Targeting Transglutaminase 2
Soo-Youl Kim, Jeffrey W. Keillor International Journal of Molecular Sciences.2020; 21(7): 2493. CrossRef - Evaluation of nuclear NF-κB, transglutaminase2, and ERCC1 as predictors of platinum resistance in testicular tumors
Alan A. Azambuja, Paula Engroff, Bruna T. Silva, Roberta C. S. Zorzetti, Fernanda B. Morrone International braz j urol.2020; 46(3): 353. CrossRef - Transglutaminase 2-Mediated p53 Depletion Promotes Angiogenesis by Increasing HIF-1α-p300 Binding in Renal Cell Carcinoma
Seon-Hyeong Lee, Joon Hee Kang, Ji Sun Ha, Jae-Seon Lee, Su-Jin Oh, Hyun-Jung Choi, Jaewhan Song, Soo-Youl Kim International Journal of Molecular Sciences.2020; 21(14): 5042. CrossRef - Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression
Burge Ulukan, Ajna Bihorac, Tarik Sipahioglu, Robert Kiraly, Laszlo Fesus, Dilek Telci ACS Omega.2020; 5(43): 28273. CrossRef - Transglutaminase 2: The Maestro of the Oncogenic Mediators in Renal Cell Carcinoma
Ayca Ece Nezir, Burge Ulukan, Dilek Telci Medical Sciences.2019; 7(2): 24. CrossRef - Transglutaminase 2 takes center stage as a cancer cell survival factor and therapy target
Richard L. Eckert Molecular Carcinogenesis.2019; 58(6): 837. CrossRef - Allosteric inhibition site of transglutaminase 2 is unveiled in the N terminus
Nayeon Kim, Joon Hee Kang, Won-Kyu Lee, Seul-Gi Kim, Jae-Seon Lee, Seon-Hyeong Lee, Jong Bae Park, Kyung-Hee Kim, Young-Dae Gong, Kwang Yeon Hwang, Soo-Youl Kim Amino Acids.2018; 50(11): 1583. CrossRef - Renal Cell Carcinoma Is Abrogated by p53 Stabilization through Transglutaminase 2 Inhibition
Seon-Hyeong Lee, Won-Kyu Lee, Nayeon Kim, Joon Kang, Kyung-Hee Kim, Seul-Gi Kim, Jae-Seon Lee, Soohyun Lee, Jongkook Lee, Jungnam Joo, Woo Kwon, Sun Rha, Soo-Youl Kim Cancers.2018; 10(11): 455. CrossRef - Tissue transglutaminase expression is necessary for adhesion, metastatic potential and cancer stemness of renal cell carcinoma
Yesim Bagatur, Ayca Zeynep Ilter Akulke, Ajna Bihorac, Merve Erdem, Dilek Telci Cell Adhesion & Migration.2017; : 1. CrossRef - Characterization of clear cell renal cell carcinoma by gene expression profiling
Bryan J. Thibodeau, Matthew Fulton, Laura E. Fortier, Timothy J. Geddes, Barbara L. Pruetz, Samreen Ahmed, Amy Banes-Berceli, Ping L. Zhang, George D. Wilson, Jason Hafron Urologic Oncology: Seminars and Original Investigations.2016; 34(4): 168.e1. CrossRef - Prognostic role of tissue transglutaminase 2 in colon carcinoma
María Jesús Fernández-Aceñero, Sofía Torres, Irene Garcia-Palmero, Cristina Díaz del Arco, J. Ignacio Casal Virchows Archiv.2016; 469(6): 611. CrossRef
|