Skip Navigation
Skip to contents

JPTM : Journal of Pathology and Translational Medicine


Author index

Page Path
HOME > Articles and issues > Author index
Sang Hyuk Lee 1 Article
Extranodal Follicular Dendritic Cell Sarcoma with Rapid Growth in Parapharynx: A Case Report
Jung-Soo Pyo, Guhyun Kang, Sung-Im Do, Seoung Wan Chae, Kyungeun Kim, Sang Hyuk Lee, Yoon-La Choi, Joon Hyuk Choi, Jin Hee Sohn, Dong-Hoon Kim
Korean J Pathol. 2012;46(3):306-310.   Published online June 22, 2012
  • 5,778 View
  • 39 Download
  • 9 Citations
AbstractAbstract PDF

Follicular dendritic cell sarcoma (FDCS) is a rare malignancy arising from the antigen-presenting cells in the lymph node and extranodal tissue. We describe a 31-year-old male patient who presented with a swelling of the left parapharynx. The radiologic findings showed a 4.7×4.5×1.9 cm-sized, ill-defined mass in the left parapharyngeal space. A fine-needle aspiration cytology was performed and it showed scattered, irregular, cohesive clusters of tumor cells with a spindle-to-ovoid shape with irregular contours in a background of lymphocytes. Based on these findings, a diagnosis of spindle cell neoplasm was made. The surgically resected tumor was composed of elongated, ovoid or polygonal cells showing positive immunohistochemistry for CD21, CD23, and CD35. Postoperatively, the residual tumor was observed to undergo a rapidly growth. There is an overlap in the cytologic and histologic findings between FDCS of the parapharynx and other tumors. Pathologists should therefore be aware of its characteristics not only to provide an accurate diagnosis but also to recommend the appropriate clinical management.


Citations to this article as recorded by  
  • Cytomorphology of follicular dendritic cell sarcoma: a report of 7 cases with an emphasis on the diagnostic challenges
    Cody Weimholt, Jalal B. Jalaly, Cedric Bailey
    Journal of the American Society of Cytopathology.2023;[Epub]     CrossRef
  • Follicular dendritic cells
    Seham A. Abd El‐Aleem, Entesar Ali Saber, Neven M. Aziz, Hani El‐Sherif, Asmaa M. Abdelraof, Laiche Djouhri
    Journal of Cellular Physiology.2022; 237(4): 2019.     CrossRef
  • Extranodal Follicular Dendritic Cell Sarcoma of the Head and Neck Region: A Clinicopathological Study of 7 Cases
    Nasir Ud Din, Zubair Ahmad, Shabina Rahim, Karen Fritchie, Muhammad Usman Tariq, Arsalan Ahmed
    International Journal of Surgical Pathology.2022; : 106689692211333.     CrossRef
  • Clinicopathological characteristics of extranodal follicular dendritic cell sarcoma: A report of two cases
    Xing Zhao, Dayong Sun, Gang Zhang
    Oncology Letters.2021;[Epub]     CrossRef
  • Cytological diagnosis of follicular dendritic cell sarcoma: A case report and review of literature
    A. Dutta, P. Arun, P. Roy, I. Arun
    Cytopathology.2018; 29(5): 461.     CrossRef
  • Follicular dendritic cells and related sarcoma
    Fabio Facchetti, Luisa Lorenzi
    Seminars in Diagnostic Pathology.2016; 33(5): 262.     CrossRef
  • Extranodal follicular dendritic cell sarcoma: A clinicopathological report of four cases and a literature review
    Oncology Letters.2015; 9(1): 391.     CrossRef
  • Follicular Dendritic Cell Sarcoma of Parapharyngeal Space: A Case Report and Review of the Literature
    Turki Al-Hussain, Muhammad Saleem, Suresh Babu Velagapudi, Mohammad Anas Dababo
    Head and Neck Pathology.2015; 9(1): 135.     CrossRef
  • Clinical and pathological features of head and neck follicular dendritic cell sarcoma
    Ji Li, Min-Li Zhou, Shui-Hong Zhou
    Hematology.2015; 20(10): 571.     CrossRef

JPTM : Journal of Pathology and Translational Medicine