- White Matter Injury of Prematurity: Its Mechanisms and Clinical Features
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Young Ah Lee
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J Pathol Transl Med. 2017;51(5):449-455. Published online August 11, 2017
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DOI: https://doi.org/10.4132/jptm.2017.07.25
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Abstract
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- A developing central nervous system is vulnerable to various insults such as infection and ischemia. While increased understanding of the dynamic nature of brain development allows a deeper insight into the pathophysiology of perinatal brain injury, the precise nature of specific fetal and neonatal brain injuries and their short- and long-term clinical consequences need special attention and further elucidation. The current review will describe the pathophysiological aspects and clinical significance of white matter injury of prematurity, a main form of perinatal brain injury in premature newborns, with a particular emphasis on its potential antenatal components.
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Citations
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