Journal of Pathology and Translational Medicine

Volume 49(2); March 2015

Reviews

Utility of Transmission Electron Microscopy in Small Round Cell Tumors: Na Rae Kim, Seung Yeon Ha, Hyun Yee Cho; J Pathol Transl Med. 2015;49(2):93-101. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.01.30

13,989 View
255 Download
5 Web of Science
4 Crossref

Small round cell tumors (SRCTs) are a heterogeneous group of neoplasms composed of small, primitive, and undifferentiated cells sharing similar histology under light microscopy. SRCTs include Ewing sarcoma/peripheral neuroectodermal tumor family tumors, neuroblastoma, desmoplastic SRCT, rhabdomyosarcoma, poorly differentiated round cell synovial sarcoma, mesenchymal chondrosarcoma, small cell osteosarcoma, small cell malignant peripheral nerve sheath tumor, and small cell schwannoma. Non-Hodgkin’s malignant lymphoma, myeloid sarcoma, malignant melanoma, and gastrointestinal stromal tumor may also present as SRCT. The current shift towards immunohistochemistry and cytogenetic molecular techniques for SRCT may be inappropriate because of antigenic overlapping or inconclusive molecular results due to the lack of differentiation of primitive cells and unavailable genetic service or limited moleculocytogenetic experience. Although usage has declined, electron microscopy (EM) remains very useful and shows salient features for the diagnosis of SRCTs. Although EM is not always required, it provides reliability and validity in the diagnosis of SRCT. Here, the ultrastructural characteristics of SRCTs are reviewed and we suggest that EM would be utilized as one of the reliable modalities for the diagnosis of undifferentiated and poorly differentiated SRCTs.

Citations

Citations to this article as recorded by

Electron Microscopy in the Context of a Children's Research Hospital
Cam Robinson
Microscopy and Microanalysis.2020; 26(S2): 1610. CrossRef
Primary bilateral corneal nerve sheath neoplasm in a dog
Marina L. Leis, M. Elyse Salpeter, Bianca S. Bauer, Dale L. Godson, Bruce H. Grahn
Veterinary Ophthalmology.2017; 20(4): 365. CrossRef
Hirnbasissyndrom infolge eines Tumors bei einer 17 Monate alten Deutsch-Holstein-Färse
Wolf Wippermann, Sandra Schöniger, Kerstin Gerlach, Gerald Fritz Schusser, Gabor Köller, Alexander Starke
Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere.2016; 44(03): 180. CrossRef
The Continuing Value of Ultrastructural Observation in Central Nervous System Neoplasms in Children
Na Rae Kim, Sung-Hye Park
Journal of Pathology and Translational Medicine.2015; 49(6): 427. CrossRef

Role of Osteal Macrophages in Bone Metabolism: Sun Wook Cho; J Pathol Transl Med. 2015;49(2):102-104. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.02.02

9,666 View
129 Download
23 Web of Science
22 Crossref

Abstract PDF

Macrophages have been shown to have pleiotropic functions in various pathophysiologies, especially in terms of anti-inflammatory and regenerative activity. Recently, the novel functions of bone marrow resident macrophages (called osteal macrophages) were intensively studied in bone development, remodeling and tissue repair processes. This review discusses the current evidence for a role of osteal macrophages in bone modeling, remodeling, and fracture healing processes.

Citations

Citations to this article as recorded by

Surgical stress induced tumor immune suppressive environment
Fan Yang, Qing Hua, Xiaoyan Zhu, Pingbo Xu
Carcinogenesis.2024; 45(4): 185. CrossRef
3D printing of gear-inspired biomaterials: Immunomodulation and bone regeneration
Xiaopeng Yu, Yufeng Wang, Meng Zhang, Hongshi Ma, Chun Feng, Bingjun Zhang, Xin Wang, Bing Ma, Qingqiang Yao, Chengtie Wu
Acta Biomaterialia.2023; 156: 222. CrossRef
Origin, production and molecular determinants of macrophages for their therapeutic targeting
Sangita Chowdhury, Arun K. Trivedi
Cell Biology International.2023; 47(1): 15. CrossRef
The Macrophage’s Role on Bone Remodeling and Osteogenesis: a Systematic Review
João Maria Orvalho, Juliana Campos Hasse Fernandes, Rogerio Moraes Castilho, Gustavo Vicentis Oliveira Fernandes
Clinical Reviews in Bone and Mineral Metabolism.2023; 21(1-4): 1. CrossRef
Neglected immunoregulation: M2 polarization of macrophages triggered by low‐dose irradiation plays an important role in bone regeneration
Shaoqing Chen, Su Ni, Chun Liu, Mu He, Yiwen Pan, Pengfei Cui, Cheng Wang, Xinye Ni
Journal of Cellular and Molecular Medicine.2023; 27(8): 1095. CrossRef
Insight into the effect of biomaterials on osteogenic differentiation of mesenchymal stem cells: A review from a mitochondrial perspective
Ziyi Feng, Meiqi Jin, Junzhi Liang, Junning Kang, Huazhe Yang, Shu Guo, Xiaoting Sun
Acta Biomaterialia.2023; 164: 1. CrossRef
Nano wear particles and the periprosthetic microenvironment in aseptic loosening induced osteolysis following joint arthroplasty
Yu Xie, Yujie Peng, Guangtao Fu, Jiewen Jin, Shuai Wang, Mengyuan Li, Qiujian Zheng, Feng-Juan Lyu, Zhantao Deng, Yuanchen Ma
Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef
Integrated computational and in vivo models reveal Key Insights into macrophage behavior during bone healing
Etienne Baratchart, Chen Hao Lo, Conor C. Lynch, David Basanta, Dominik Wodarz
PLOS Computational Biology.2022; 18(5): e1009839. CrossRef
Strategies of Macrophages to Maintain Bone Homeostasis and Promote Bone Repair: A Narrative Review
Yingkun Hu, Jinghuan Huang, Chunying Chen, Yi Wang, Zhuowen Hao, Tianhong Chen, Junwu Wang, Jingfeng Li
Journal of Functional Biomaterials.2022; 14(1): 18. CrossRef
Macrophages and Stem Cells—Two to Tango for Tissue Repair?
Emilia Manole, Cristina Niculite, Ioana Maria Lambrescu, Gisela Gaina, Octavian Ioghen, Laura Cristina Ceafalan, Mihail Eugen Hinescu
Biomolecules.2021; 11(5): 697. CrossRef
Bone remodeling stages under physiological conditions and glucocorticoid in excess: Focus on cellular and molecular mechanisms
V. V. Povoroznyuk, N. V. Dedukh, M. A. Bystrytska, V. S. Shapovalov
Regulatory Mechanisms in Biosystems.2021; 12(2): 212. CrossRef
Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells
Asim Cengiz Akbulut, Grzegorz B. Wasilewski, Nikolas Rapp, Francesco Forin, Heike Singer, Katrin J. Czogalla-Nitsche, Leon J. Schurgers
Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef
The Effects of Biomaterial Implant Wear Debris on Osteoblasts
Li Zhang, El-Mustapha Haddouti, Kristian Welle, Christof Burger, Dieter C. Wirtz, Frank A. Schildberg, Koroush Kabir
Frontiers in Cell and Developmental Biology.2020;[Epub] CrossRef
Local Cellular Responses to Metallic and Ceramic Nanoparticles from Orthopedic Joint Arthroplasty Implants

Li Zhang, El-Mustapha Haddouti, Kristian Welle, Christof Burger, Koroush Kabir, Frank A Schildberg
International Journal of Nanomedicine.2020; Volume 15: 6705. CrossRef
Mesenchymal stem cell-macrophage crosstalk and bone healing
Jukka Pajarinen, Tzuhua Lin, Emmanuel Gibon, Yusuke Kohno, Masahiro Maruyama, Karthik Nathan, Laura Lu, Zhenyu Yao, Stuart B. Goodman
Biomaterials.2019; 196: 80. CrossRef
Inflammation, mesenchymal stem cells and bone regeneration
Hongrui Liu, Dongfang Li, Yi Zhang, Minqi Li
Histochemistry and Cell Biology.2018; 149(4): 393. CrossRef
Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non‐invasive murine model of post‐traumatic osteoarthritis
Sophie J. Gilbert, Cleo S. Bonnet, Paulina Stadnik, Victor C. Duance, Deborah J. Mason, Emma J. Blain
Journal of Orthopaedic Research.2018; 36(8): 2118. CrossRef
M2 macrophages are closely associated with accelerated clavicle fracture healing in patients with traumatic brain injury: a retrospective cohort study
Ran Zhang, Yi Liang, Shuxiang Wei
Journal of Orthopaedic Surgery and Research.2018;[Epub] CrossRef
Digesting the role of bone marrow macrophages on hematopoiesis
Esther Heideveld, Emile van den Akker
Immunobiology.2017; 222(6): 814. CrossRef
Concise Review: Stem Cells in Osteoimmunology
Fernando A. Fierro, Jan A. Nolta, Iannis E. Adamopoulos
Stem Cells.2017; 35(6): 1461. CrossRef
Aging, inflammation, stem cells, and bone healing
Emmanuel Gibon, Laura Lu, Stuart B. Goodman
Stem Cell Research & Therapy.2016;[Epub] CrossRef
The roles of immune cells in bone healing; what we know, do not know and future perspectives
Jehan J. El-Jawhari, Elena Jones, Peter V. Giannoudis
Injury.2016; 47(11): 2399. CrossRef

Original Articles

Overexpression of C-reactive Protein as a Poor Prognostic Marker of Resectable Hepatocellular Carcinomas: Jin Ho Shin, Chong Jai Kim, Eun Jeong Jeon, Chang Ohk Sung, Hwa Jeong Shin, Jene Choi, Eunsil Yu; J Pathol Transl Med. 2015;49(2):105-111. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.01.19

10,582 View
75 Download
20 Web of Science
14 Crossref

Abstract PDF

Background
C-reactive protein (CRP) is an acute phase reactant synthesized in the liver. CRP immunoreactivity is a feature of inflammatory hepatocellular adenomas with a higher risk of malignant transformation. A high serum CRP level denotes poor prognosis in hepatocellular carcinoma (HCC) patients. This study was conducted to determine whether CRP is produced in HCC and to assess the clinicopathologic significance of CRP expression in cancer cells. Methods: CRP immunoreactivity was examined in treatment-naïve HCCs (n=224) using tissue microarrays and was correlated with clinicopathologic parameters. The expression of CRP mRNA and protein was also assessed in 12 HCC cases by quantitative real-time polymerase chain reaction and immunoblotting. Hep3B and SNU-449 HCC cell lines were used for the analysis of CRP mRNA regulation by interleukin 6 (IL-6). Results: CRP was expressed in 133 of 224 HCCs (59.4%) with a variable degree of immunoreactivity (grade 1 in 25.9%; grade 2 in 20.1%; grade 3 in 13.4%). There was an inverse relationship between grade 3 CRP immunoreactivity and cancer-specific survival (p=.0047), while no associations were found with other parameters, including recurrence-free survival. The CRP mRNA expression level was significantly higher in CRP immunopositive cases than in immunonegative cases (p<.05). CRP mRNA expression was increased in Hep3B cells, but was not detected in SNU-449 cells even after IL-6 treatment. Conclusions: We report the expression of CRP in HCC for the first time. CRP expression was associated with poor cancer-specific survival in patients with resectable HCC.

Citations

Citations to this article as recorded by

Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma
Sofi Sennefelt Nyman, Angeliki Dimopoulou Creusen, Ulf Johnsson, Fredrik Rorsman, Johan Vessby, Charlotte Ebeling Barbier
Acta Radiologica.2022; 63(10): 1323. CrossRef
The quest for precision oncology with immune checkpoint inhibitors for hepatocellular carcinoma
Giuseppe Cabibbo, Amit G. Singal
Journal of Hepatology.2022; 76(2): 262. CrossRef
HNF-1β is a More Sensitive and Specific Marker Than C-Reactive Protein for Identifying Biliary Differentiation in Primary Hepatic Carcinomas
Pallavi A. Patil, Tamar Taddei, Dhanpat Jain, Xuchen Zhang
Archives of Pathology & Laboratory Medicine.2022; 146(2): 220. CrossRef
Malignant transformation of hepatocellular adenoma
Céline Julien, Brigitte Le Bail, Laurence Chiche, Charles Balabaud, Paulette Bioulac-Sage
JHEP Reports.2022; 4(3): 100430. CrossRef
Effect of Treatment with Colchicine after Acute Coronary Syndrome on Major Cardiovascular Events: A Systematic Review and Meta-Analysis of Clinical Trials
Erfan Razavi, Akam Ramezani, Asma Kazemi, Armin Attar, Baohui Xu
Cardiovascular Therapeutics.2022; 2022: 1. CrossRef
Steatotic and Steatohepatitic Hepatocellular Carcinomas
Umut Aykutlu, Asuman Argon, Mehmet Orman, Sezgin Ulukaya, Murat Zeytunlu, Zeki Karasu, Fulya Günşar, Deniz Nart, Ulus Akarca, Funda Yilmaz
American Journal of Surgical Pathology.2021; 45(9): 1252. CrossRef
Cytochrome P450 4A11 expression in tumor cells: A favorable prognostic factor for hepatocellular carcinoma patients
Hyuk Soo Eun, Sang Yeon Cho, Byung Seok Lee, Sup Kim, In‐Sang Song, Kwangsik Chun, Cheong‐Hae Oh, Min‐Kyung Yeo, Seok Hyun Kim, Kyung‐Hee Kim
Journal of Gastroenterology and Hepatology.2019; 34(1): 224. CrossRef
Investigating Trk Protein Expression between Oropharyngeal and Non-oropharyngeal Squamous Cell Carcinoma: Clinical Implications and Possible Roles of Human Papillomavirus Infection
Yoon Ah Cho, Ji Myung Chung, Hyunmi Ryu, Eun Kyung Kim, Byoung Chul Cho, Sun Och Yoon
Cancer Research and Treatment.2019; 51(3): 1052. CrossRef
Increased systemic zonula occludens 1 associated with inflammation and independent biomarker in patients with hepatocellular carcinoma
Amit Kumar Ram, Biju Pottakat, Balasubramaniyan Vairappan
BMC Cancer.2018;[Epub] CrossRef
C-reactive Protein Overexpression in the Background Liver of Hepatitis B Virus–Associated Hepatocellular Carcinoma Is a Prognostic Biomarker
Jin Ho Shin, Eunsil Yu, Eun Na Kim, Chong Jai Kim
Journal of Pathology and Translational Medicine.2018; 52(5): 267. CrossRef
Efficacy of vasopressin V2 receptor antagonist tolvaptan in treatment of hepatic edema
Yasunari Hiramine, Hirofumi Uto, Yasushi Imamura, Takuya Hiwaki, Takeshi Kure, Sho Ijuin, Kohei Oda, Seiichi Mawatari, Kotaro Kumagai, Koki Tokunaga, Hirofumi Higashi, Ichiro Kanetsuki, Osamu Kubozono, Shigeho Maenohara, Akio Ido
Hepatology Research.2017; 47(6): 542. CrossRef
Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis
Stefan Janik, Christine Bekos, Philipp Hacker, Thomas Raunegger, Bahil Ghanim, Elisa Einwallner, Lucian Beer, Walter Klepetko, Leonhard Müllauer, Hendrik J. Ankersmit, Bernhard Moser
Oncotarget.2017; 8(29): 47090. CrossRef
Pretreatment neutrophil-to-lymphocyte ratio predicts prognosis in patients with metastatic renal cell carcinoma receiving targeted therapy
Gui-Ming Zhang, Yao Zhu, Wei-Jie Gu, Hai-Liang Zhang, Guo-Hai Shi, Ding-Wei Ye
International Journal of Clinical Oncology.2016; 21(2): 373. CrossRef
Current Proceedings in the Molecular Dissection of Hepatocellular Adenomas: Review and Hands-on Guide for Diagnosis
Diane Goltz, Hans-Peter Fischer
International Journal of Molecular Sciences.2015; 16(9): 20994. CrossRef

The Diagnostic Usefulness of HMGA2, Survivin, CEACAM6, and SFN/14-3-3 δ in Follicular Thyroid Carcinoma: Min Hye Jang, Kyeong Cheon Jung, Hye Sook Min; J Pathol Transl Med. 2015;49(2):112-117. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.01.31

7,840 View
70 Download
11 Web of Science
12 Crossref

Abstract PDF

Background
Follicular thyroid carcinoma (FTC) is the second most common thyroid malignancy and its differential diagnosis includes follicular adenoma (FA) and adenomatous goiter (AG). Several ancillary markers have been suggested to aid in the diagnosis of FTC, but the successful use of these methods still needs to be validated. Methods: In the present study, we verified the immunoexpression of HMGA2, CEACAM6, survivin, and SFN/14-3-3 δ in lesions including 41 AGs, 72 FAs, and 79 FTCs. We evaluated their diagnostic usefulness, combined with galectin 3, Hector Battifora mesothelial 1 (HBME1), cytokeratin 19, and cyclin D1, in diagnosing FTC. Results: The expressions of HBME1 (65.8%) and HMGA2 (55.7%) were significantly higher in FTCs than in FAs and AGs (p<.001 and p=.005, respectively). HBME1 was the only marker that was more frequently expressed in FTCs than in FAs (p=.021) and it was more frequently expressed in follicular neoplasms than in AGs (p<.001). Among the novel markers, the combination of HMGA2 and HBME1 showed the highest sensitivity (72.2%) and specificity (76.1%) for diagnosing FTC. CEACAM6, survivin, and SFN/14-3-3 δ were barely expressed in most cases. Conclusions: Our present results show that only HMGA2 can be beneficial in differentiating FTC using the novel markers.

Citations

Citations to this article as recorded by

HMGA2 promotes nasopharyngeal carcinoma progression and is associated with tumor resistance and poor prognosis
Xinting Ouyang, Kangxin Li, Jiaqi Wang, Weijian Zhu, Qiang Yi, Jinghua Zhong
Frontiers in Oncology.2024;[Epub] CrossRef
miR‐98‐5p promotes apoptosis and inhibits migration and cell growth in papillary thyroid carcinoma through Bax/Caspase‐3 by HMGA2
Kai Qiu, QingJi Xie, Shan Jiang, Ting Lin
Journal of Clinical Laboratory Analysis.2020;[Epub] CrossRef
High mobility group A protein-2 as a tumor cancer diagnostic and prognostic marker: a systematic review and meta-analysis
Yen Thi-Hai Pham, Ovie Utuama, Claire E. Thomas, Jong A. Park, Carlo La Vecchia, Harvey A. Risch, Chi Thi-Du Tran, Thanh V. Le, Paolo Boffetta, Leon Raskin, Hung N. Luu
European Journal of Cancer Prevention.2020; 29(6): 565. CrossRef
Diagnostic performance of HMGA2 gene expression for differentiation of malignant thyroid nodules: A systematic review and meta‐analysis
Bo Hyun Kim, Seong Jang Kim, Mijin Kim, Sang‐Woo Lee, Shin Young Jeong, Kyoungjune Pak, Keunyoung Kim, In Joo Kim
Clinical Endocrinology.2018; 89(6): 856. CrossRef
Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution
Geneviève Dom, Sandra Frank, Sebastien Floor, Pashalina Kehagias, Frederick Libert, Catherine Hoang, Guy Andry, Alex Spinette, Ligia Craciun, Nicolas de Saint Aubin, Christophe Tresallet, Frederique Tissier, Frederique Savagner, Samira Majjaj, Ilse Gutier
Oncotarget.2018; 9(12): 10343. CrossRef
APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions
Esmeralda Castelblanco, Carles Zafon, Javier Maravall, Pilar Gallel, Montserrat Martinez, Ismael Capel, Maria Rosa Bella, Irene Halperin, Jordi Temprana, Carmela Iglesias, Manel Puig-Domingo, Mercedes Robledo, Xavier Matias-Guiu, Didac Mauricio
Thyroid.2017; 27(1): 59. CrossRef
Prognostic implication of histological features associated with EHD2 expression in papillary thyroid carcinoma
Yourha Kim, Min-Hee Kim, Sora Jeon, Jeeyoon Kim, Chankyung Kim, Ja Seong Bae, Chan Kwon Jung, Yves St-Pierre
PLOS ONE.2017; 12(3): e0174737. CrossRef
Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
Joanna Waligórska-Stachura, Nadia Sawicka-Gutaj, Maciej Zabel, Mirosław Andrusiewicz, Paweł Gut, Agata Czarnywojtek, Marek Ruchała
Oncology Letters.2017; 13(4): 2437. CrossRef
High-Frequency Ultrasound-Guided Injection for the Generation of a Novel Orthotopic Mouse Model of Human Thyroid Carcinoma
Adelaide Greco, Sandra Albanese, Luigi Auletta, Peppino Mirabelli, Antonella Zannetti, Crescenzo D'Alterio, Gennaro Di Maro, Francesca Maria Orlandella, Giuliana Salvatore, Andrea Soricelli, Marco Salvatore
Thyroid.2016; 26(4): 552. CrossRef
The study of galectin-3, Ki-67, ubiquitin, HMGA-2 by polymerase chain reaction in real time (RT-PCR) in the puncture specimens of nodular goiter
Irina S. Berjozkina, Tat'jana V. Saprina, Anastasija P. Zima, Anna V. Isaeva, Venera N. Latipova, Marat R. Muhamedov, Leonid R. Bazilevich, Oleg S. Popov, Dar'ja A. Skuratovskaja, Kristina A. Jurova, Larisa C. Litvinova
Clinical and experimental thyroidology.2016; 12(2): 19. CrossRef
High-mobility group A2 overexpression is an unfavorable prognostic biomarker for nasopharyngeal carcinoma patients
Zhuoxing Liu, Kunpeng Wu, Zhixiong Yang, Aibing Wu
Molecular and Cellular Biochemistry.2015; 409(1-2): 155. CrossRef
Defining the value of CD56, CK19, Galectin 3 and HBME-1 in diagnosis of follicular cell derived lesions of thyroid with systematic review of literature
Duško Dunđerović, Jasmina Marković Lipkovski, Ivan Boričic, Ivan Soldatović, Vesna Božic, Dubravka Cvejić, Svetislav Tatić
Diagnostic Pathology.2015;[Epub] CrossRef

Pathologic Factors Associated with Prognosis after Adjuvant Chemotherapy in Stage II/III Microsatellite-Unstable Colorectal Cancers: Jung Ho Kim, Jeong Mo Bae, Hyeon Jeong Oh, Hye Seung Lee, Gyeong Hoon Kang; J Pathol Transl Med. 2015;49(2):118-128. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.02.05

10,600 View
117 Download
18 Web of Science
14 Crossref

Abstract PDF

Background
Although there are controversies regarding the benefit of fluoropyrimidine-based adjuvant chemotherapy in patients with microsatellite instability–high (MSI-H) colorectal cancer (CRC), the pathologic features affecting postchemotherapeutic prognosis in these patients have not been fully identified yet. Methods: A total of 26 histopathologic and immunohistochemical factors were comprehensively evaluated in 125 stage II or III MSI-H CRC patients who underwent curative resection followed by fluoropyrimidine-based adjuvant chemotherapy. We statistically analyzed the associations of these factors with disease-free survival (DFS). Results: Using a Kaplan- Meier analysis with log-rank test, we determined that ulceroinfiltrative gross type (p=.003), pT4 (p<.001), pN2 (p=.002), perineural invasion (p=.001), absence of peritumoral lymphoid reaction (p=.041), signet ring cell component (p=.006), and cribriform comedo component (p=.004) were significantly associated with worse DFS in patients receiving oxaliplatin-based adjuvant chemotherapy (n=45). By contrast, pT4 (p<.001) and tumor budding-positivity (p=.032) were significant predictors of poor survival in patients receiving non-oxaliplatin–based adjuvant chemotherapy (n=80). In Cox proportional hazards regression model-based univariate and multivariate analyses, pT category (pT1-3 vs pT4) was the only significant prognostic factor in patients receiving non-oxaliplatin–based adjuvant chemotherapy, whereas pT category, signet ring cell histology and cribriform comedo histology remained independent prognostic factors in patients receiving oxaliplatin-based adjuvant chemotherapy. Conclusions: pT4 status is the most significant pathologic determinant of poor outcome after fluoropyrimidine-based adjuvant chemotherapy in patients with stage II/III MSI-H CRC.

Citations

Citations to this article as recorded by

Cribriform colon cancer: a morphological growth pattern associated with extramural venous invasion, nodal metastases and microsatellite stability
Alexander S Taylor, Natalia Liu, Jiayun M Fang, Nicole Panarelli, Lili Zhao, Jerome Cheng, Purva Gopal, Suntrea Hammer, Jing Sun, Henry Appelman, Maria Westerhoff
Journal of Clinical Pathology.2022; 75(7): 483. CrossRef
HSP110 as a Diagnostic but Not a Prognostic Biomarker in Colorectal Cancer With Microsatellite Instability
Gaelle Tachon, Arnaud Chong-Si-Tsaon, Thierry Lecomte, Audelaure Junca, Éric Frouin, Elodie Miquelestorena-Standley, Julie Godet, Camille Evrard, Violaine Randrian, Romain Chautard, Marie-Luce Auriault, Valérie Moulin, Serge Guyetant, Gaelle Fromont, Luci
Frontiers in Genetics.2022;[Epub] CrossRef
Comparative expression of immunohistochemical biomarkers in cribriform and pattern 4 non-cribriform prostatic adenocarcinoma
Guang-Qian Xiao, Elise Nguyen, Pamela D. Unger, Andy E. Sherrod
Experimental and Molecular Pathology.2020; 114: 104400. CrossRef
Prognostic Predictability of American Joint Committee on Cancer 8th Staging System for Perihilar Cholangiocarcinoma: Limited Improvement Compared with the 7th Staging System
Jong Woo Lee, Jae Hoon Lee, Yejong Park, Woohyung Lee, Jaewoo Kwon, Ki Byung Song, Dae Wook Hwang, Song Cheol Kim
Cancer Research and Treatment.2020; 52(3): 886. CrossRef
Prognostic predictability of the new American Joint Committee on Cancer 8th staging system for distal bile duct cancer: limited usefulness compared with the 7th staging system
Jae Seung Kang, Seungyeoun Lee, Donghee Son, Youngmin Han, Kyung Bun Lee, Jae Ri Kim, Wooil Kwon, Sun‐Whe Kim, Jin‐Young Jang
Journal of Hepato-Biliary-Pancreatic Sciences.2018; 25(2): 124. CrossRef
Invasion Depth Measured in Millimeters is a Predictor of Survival in Patients with Distal Bile Duct Cancer: Decision Tree Approach
Kyueng‐Whan Min, Dong‐Hoon Kim, Byoung Kwan Son, Eun‐Kyung Kim, Sang Bong Ahn, Seong Hwan Kim, Yun Ju Jo, Young Sook Park, Jinwon Seo, Young Ha Oh, Sukjoong Oh, Ho Young Kim, Mi Jung Kwon, Soo Kee Min, Hye‐Rim Park, Ji‐Young Choe, Jang Yong Jeon, Hong Il
World Journal of Surgery.2017; 41(1): 232. CrossRef
BRAF-Mutated Colorectal Cancer Exhibits Distinct Clinicopathological Features from Wild-TypeBRAF-Expressing Cancer Independent of the Microsatellite Instability Status
Min Hye Jang, Sehun Kim, Dae Yong Hwang, Wook Youn Kim, So Dug Lim, Wan Seop Kim, Tea Sook Hwang, Hye Seung Han
Journal of Korean Medical Science.2017; 32(1): 38. CrossRef
Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma
Hye Eun Park, Jung Ho Kim, Nam-Yun Cho, Hye Seung Lee, Gyeong Hoon Kang
Virchows Archiv.2017; 471(3): 329. CrossRef
Dominant high expression of wild‐type HSP110 defines a poor prognostic subgroup of colorectal carcinomas with microsatellite instability: a whole‐section immunohistochemical analysis
Hyeon Jeong Oh, Jung Ho Kim, Tae Hun Lee, Hye Eun Park, Jeong Mo Bae, Hye Seung Lee, Gyeong Hoon Kang
APMIS.2017; 125(12): 1076. CrossRef
TNM Staging of Colorectal Cancer Should be Reconsidered According to Weighting of the T Stage
Jun Li, Cheng-Hao Yi, Ye-Ting Hu, Jin-Song Li, Ying Yuan, Su-Zhan Zhang, Shu Zheng, Ke-Feng Ding
Medicine.2016; 95(6): e2711. CrossRef
Molecular genetics of colorectal cancer
James Church
Seminars in Colon and Rectal Surgery.2016; 27(4): 172. CrossRef
Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers
Jung Ho Kim, Hye Eun Park, Nam-Yun Cho, Hye Seung Lee, Gyeong Hoon Kang
British Journal of Cancer.2016; 115(4): 490. CrossRef
Distinct features betweenMLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway
Jung Ho Kim, Jeong Mo Bae, Nam-Yun Cho, Gyeong Hoon Kang
Oncotarget.2016; 7(12): 14095. CrossRef
Tumor deposits: markers of poor prognosis in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy
Lu-Ning Zhang, Wei-Wei Xiao, Shao-Yan Xi, Pu-Yun OuYang, Kai-Yun You, Zhi-Fan Zeng, Pei-Rong Ding, Hui-Zhong Zhang, Zhi-Zhong Pan, Rui-Hua Xu, Yuan-Hong Gao
Oncotarget.2016; 7(5): 6335. CrossRef

Image-Guided Fine Needle Cytology with Aspiration Versus Non-Aspiration in Retroperitoneal Masses: Is Aspiration Necessary?: Rajiv Kumar Misra, Shaila Mitra, Rishav Kumar Jain, Shilpa Vahikar, Archana Bundela, Purak Misra; J Pathol Transl Med. 2015;49(2):129-135. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.01.28

7,484 View
64 Download
5 Web of Science
6 Crossref

Abstract PDF

Background
Although using fine needle cytology with aspiration (FNC-A) for establishing diagnoses in the retroperitoneal region has shown promise, there is scant literature supporting a role of non-aspiration cytology (FNC-NA) for this region. We assessed the accuracy and reliability of FNC-A and FNC-NA as tools for preoperative diagnosis of retroperitoneal masses and compared the results of both techniques with each other and with histopathology. Methods: Fifty-seven patients with retroperitoneal masses were subjected to FNC-A and FNC-NA. Smears were stained with May-Grunwald Giemsa and hematoxylin and eosin stain. An individual slide was objectively analysed using a point scoring system to enable comparison between FNC-A and FNC-NA. Results: By FNC-A, 91.7% accuracy was obtained in cases of retroperitoneal lymph node lesions followed by renal masses (83.3%). The diagnostic accuracy of other sites by FNC-A varied from 75.0%–81.9%. By FNC-NA, 93.4% diagnostically accurate results were obtained in the kidney, followed by 75.0% in adrenal masses. The diagnostic accuracy of other sites by FNC-NA varied from 66.7%–72.8%. Conclusions: Although both techniques have their own advantages and disadvantages, FNC-NA may be a more efficient adjuvant method of sampling in retroperitoneal lesions.

Citations

Citations to this article as recorded by

A comparison of cytologic quality in fine‐needle specimens obtained with and without aspiration from superficial lymph nodes in the dog
V. Karakitsou, M. M. Christopher, E. Meletis, P. Kostoulas, D. Pardali, C. K. Koutinas, M. E. Mylonakis
Journal of Small Animal Practice.2022; 63(1): 16. CrossRef
A comparison of cytological quality between fine‐needle aspiration and non‐aspiration techniques for obtaining ultrasound‐guided samples from canine and feline lymph nodes
James Whitlock, Olivier Taeymans, Paola Monti
Veterinary Record.2021;[Epub] CrossRef
A randomised controlled comparison of aspiration and non-aspiration fine-needle techniques for obtaining ultrasound-guided cytological samples from canine livers
K.L. Fleming, E.J. Howells, E.J. Villiers, T.W. Maddox
The Veterinary Journal.2019; 252: 105372. CrossRef
Minimally invasive biopsy in retroperitoneal tumors (Review)
Radu Marcu, Camelia Diaconu, Traian Constantin, Bogdan Socea, Florentina Ionita‑Radu, Dan Mischianu, Ovidiu Bratu
Experimental and Therapeutic Medicine.2019;[Epub] CrossRef
For diagnosis of liver masses, fine-needle aspiration versus needle core biopsy: which is better?
Liye Suo, Ruby Chang, Vijayalakshmi Padmanabhan, Shilpa Jain
Journal of the American Society of Cytopathology.2018; 7(1): 46. CrossRef
Fine needle aspiration in retroperitoneal lesions
Parikshaa Gupta, Arvind Rajwanshi, Raje Nijhawan, Radhika Srinivasan, Nalini Gupta, Uma Nahar Saikia, Pranab Dey
APMIS.2017; 125(1): 16. CrossRef

Accuracy of Core Needle Biopsy Versus Fine Needle Aspiration Cytology for Diagnosing Salivary Gland Tumors: In Hye Song, Joon Seon Song, Chang Ohk Sung, Jong-Lyel Roh, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim, Jeong Hyun Lee, Jung Hwan Baek, Kyung-Ja Cho; J Pathol Transl Med. 2015;49(2):136-143. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.01.03

10,588 View
185 Download
66 Web of Science
63 Crossref

Abstract PDF

Background
Core needle biopsy is a relatively new technique used to diagnose salivary gland lesions, and its role in comparison with fine needle aspiration cytology needs to be refined. Methods: We compared the results of 228 ultrasound-guided core needle biopsy and 371 fine needle aspiration procedures performed on major salivary gland tumors with their postoperative histological diagnoses. Results: Core needle biopsy resulted in significantly higher sensitivity and more accurate tumor subtyping, especially for malignant tumors, than fine needle aspiration. No patient developed major complications after core needle biopsy. Conclusions: We recommend ultrasoundguided core needle biopsy as the primary diagnostic tool for the preoperative evaluation of patients with salivary gland lesions, especially when malignancy is suspected.

Citations

Citations to this article as recorded by

Giant Pleomorphic Adenoma of Submandibular Gland
Harendra Kumar, Qazi Saquib Rizwan, Mayank Gupta, Tarun Kumar
Indian Journal of Otolaryngology and Head & Neck Surgery.2024; 76(1): 1361. CrossRef
CT-guided core needle biopsies of head and neck tumors: a comprehensive monocenter analysis of safety and outcomes
Thomas Joseph Vogl, Heinrich Johannes Ketelsen, Scherwin Mahmoudi, Jan-Erik Scholtz, Vitali Koch, Leon David Grünewald, Peter Wild, Timo Stoever, Simon Bernatz
European Radiology.2024;[Epub] CrossRef
Indications for Submandibulectomy Within a 20-Year Period
Amir Bolooki, Anna Stenzl, Christopher Weusthof, Benedikt Hofauer
Ear, Nose & Throat Journal.2024;[Epub] CrossRef
The Usefulness of Ultrasound-Guided Core Needle Biopsy Compared to Fine Needle Aspiration in Pre-Operative Diagnosis of Cystic-Predominant Parotid Tumors
Youn Jin Cho, Young Rok Jo, Hyun Jun Hong, Hye Ran Lee
Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2023; 66(8): 532. CrossRef
The Value of Ultrasound-guided Core Needle Biopsy in Differentiating Benign from Malignant Salivary Gland Lesions
Mohammad Ali Kazemi, Farzaneh Amini, Bita Kargar, Maryam Lotfi, Keyvan Aghazadeh, Hashem Sharifian, Behnaz Moradi, Javid Azadbakht
Indian Journal of Otolaryngology and Head & Neck Surgery.2023; 75(2): 266. CrossRef
Schnellschnittdiagnostik bei Tumoren des Trigonum submandibulare
S. Riemann, A. Knopf
HNO.2023; 71(3): 164. CrossRef
Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Submandibular Gland: A Case Report
Georgia Syrnioti, Antonia Syrnioti, Alharith Abdullah, Xuehui Lui, Ernesto Mendoza
Cureus.2023;[Epub] CrossRef
Intraductal Carcinoma: The Carcinoma In Situ of the Salivary Gland
Rhema Thomas, Tijjani Umar, Farzad Borumandi
Journal of Craniofacial Surgery.2023; 34(5): e432. CrossRef
Fine-Needle Aspiration Cytology for Parotid Tumors
Masataka Taniuchi, Tetsuya Terada, Ryo Kawata
Life.2022; 12(11): 1897. CrossRef
Utility of the Milan System for Reporting Salivary Gland Cytology, with focus on the incidence and histologic correlates of atypia of undetermined significance (AUS) and salivary gland neoplasm of uncertain malignant potential (SUMP): A 3‐year institution
Christopher M. Cormier, Shweta Agarwal
Cancer Cytopathology.2022; 130(4): 303. CrossRef
Percutaneous CT-Guided Core Needle Biopsies of Head and Neck Masses: Review of 184 Cases at a Single Academic Institution, Common and Special Techniques, Diagnostic Yield, and Safety
R.W. Jordan, D.P. Shlapak, J.C. Benson, F.E. Diehn, D.K. Kim, V.T. Lehman, G.B. Liebo, A.A. Madhavan, J.M. Morris, P.P. Morris, J.T. Verdoorn, C.M. Carr
American Journal of Neuroradiology.2022; 43(1): 117. CrossRef
Nodular fasciitis of the submandibular gland
Ting Suen Wong, Richard Wei Chern Gan, Laszlo Karsai, Bun Yin Winson Wong
BMJ Case Reports.2022; 15(4): e245584. CrossRef
Validation of the Milan system for reporting salivary gland cytopathology: a single institution’s 10-year experience
Christopher Felicelli, Joseph Reznicek, Yevgen Chornenkyy, Lucy Jager, Daniel Johnson
Journal of the American Society of Cytopathology.2022; 11(5): 264. CrossRef
Application of the Milan system for reporting salivary gland cytopathology using cell blocks
Grégoire B. Morand, Raihanah Alsayegh, Alex M. Mlynarek, Marianne Plourde, Tiffany Mach, Marco A. Mascarella, Michael P. Hier, Livia Florianova, Marc P. Pusztaszeri
Virchows Archiv.2022; 481(4): 575. CrossRef
Comparisons among the Ultrasonography Prediction Model, Real-Time and Shear Wave Elastography in the Evaluation of Major Salivary Gland Tumors
Ping-Chia Cheng, Wu-Chia Lo, Chih-Ming Chang, Ming-Hsun Wen, Po-Wen Cheng, Li-Jen Liao
Diagnostics.2022; 12(10): 2488. CrossRef
A Novel Sonographic Scoring Model in the Prediction of Major Salivary Gland Tumors
Wu‐Chia Lo, Chih‐Ming Chang, Chi‐Te Wang, Po‐Wen Cheng, Li‐Jen Liao
The Laryngoscope.2021;[Epub] CrossRef
Assessing the diagnostic accuracy for pleomorphic adenoma and Warthin tumor by employing the Milan System for Reporting Salivary Gland Cytopathology: An international, multi‐institutional study
Derek B. Allison, Alexander P. Smith, Daniel An, James Adam Miller, Khurram Shafique, Sharon Song, Kartik Viswanathan, Elizabeth Eykman, Rema A. Rao, Austin Wiles, Güliz A. Barkan, Ritu Nayar, Guido Fadda, Celeste N. Powers, Esther Diana Rossi, Momin T. S
Cancer Cytopathology.2021; 129(1): 43. CrossRef
Magnetic resonance imaging of salivary gland tumours: Key findings for imaging characterisation
Davide Maraghelli, Michele Pietragalla, Cesare Cordopatri, Cosimo Nardi, Anna Julie Peired, Giandomenico Maggiore, Stefano Colagrande
European Journal of Radiology.2021; 139: 109716. CrossRef
The Milan System, from Its Introduction to Its Current Adoption in the Diagnosis of Salivary Gland Cytology
Esther Diana Rossi
Journal of Molecular Pathology.2021; 2(2): 114. CrossRef
Utility of the Milan system for reporting salivary gland cytopathology during rapid on‐site evaluation (ROSE) of salivary gland aspirates
Aanchal Kakkar, Mukin Kumar, Priyadarsani Subramanian, Arshad Zubair, Rajeev Kumar, Alok Thakar, Deepali Jain, Sandeep R. Mathur, Venkateswaran K. Iyer
Cytopathology.2021; 32(6): 779. CrossRef
Contribution of small tissue biopsy and flow cytometry to preoperative cytological categorization of salivary gland fine needle aspirates according to the Milan System: Single center experience on 287 cases
Tolga Bağlan, Serpil Dizbay Sak, Cevriye Cansız Ersöz, Koray Ceyhan
Diagnostic Cytopathology.2021; 49(4): 509. CrossRef
Is Milan for kids?: The Milan System for Reporting Salivary Gland Cytology in pediatric patients at an academic children's hospital with cytologic‐histologic correlation
Swati P. Satturwar, Maren Y. Fuller, Sara E. Monaco
Cancer Cytopathology.2021; 129(11): 884. CrossRef
Radiographic Interpretation in Oral Medicine and Hospital Dental Practice
Katherine France, Anwar A.A.Y. AlMuzaini, Mel Mupparapu
Dental Clinics of North America.2021; 65(3): 509. CrossRef
Carcinoma ex pleomorphic adenoma of major salivary glands: CT and MR imaging findings
Can Wang, Qiang Yu, Siyi Li, Jingjing Sun, Ling Zhu, Pingzhong Wang
Dentomaxillofacial Radiology.2021; 50(7): 20200485. CrossRef
Salivary gland carcinoma in children and adolescents: The EXPeRT/PARTNER diagnosis and treatment recommendations
Aurore Surun, Dominik T. Schneider, Andrea Ferrari, Teresa Stachowicz‐Stencel, Jelena Rascon, Anna Synakiewicz, Abbas Agaimy, Kata Martinova, Denis Kachanov, Jelena Roganovic, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Frédéric Kolb, Juliette Thariat, Anto
Pediatric Blood & Cancer.2021;[Epub] CrossRef
A Call for Universal Acceptance of the Milan System for Reporting Salivary Gland Cytopathology
Eric Barbarite, Sidharth V. Puram, Adeeb Derakhshan, Esther D. Rossi, William C. Faquin, Mark A. Varvares
The Laryngoscope.2020; 130(1): 80. CrossRef
Preoperative biopsy in parotid malignancies: Variation in use and impact on surgical margins
Liliya Benchetrit, Sina J. Torabi, Elliot Morse, Saral Mehra, Rahmatullah Rahmati, Heather A. Osborn, Benjamin L. Judson
The Laryngoscope.2020; 130(6): 1450. CrossRef
α‐Synuclein Real‐Time Quaking‐Induced Conversion in the Submandibular Glands of Parkinson's Disease Patients
Sireesha Manne, Naveen Kondru, Huajun Jin, Vellareddy Anantharam, Xuemei Huang, Arthi Kanthasamy, Anumantha G. Kanthasamy
Movement Disorders.2020; 35(2): 268. CrossRef
The Accessory Parotid Gland and its Clinical Significance
Mateusz A. Rosa, Dominik P. Łazarz, Jakub R. Pękala, Bendik Skinningsrud, Sigurd S. Lauritzen, Bernard Solewski, Przemysław A. Pękala, Jerzy A. Walocha, Krzysztof A. Tomaszewski
Journal of Craniofacial Surgery.2020; 31(3): 856. CrossRef
Comparison of core needle biopsy and fine‐needle aspiration in diagnosis of ma lignant salivary gland neoplasm: Systematic review and meta‐analysis
Jungheum Cho, Junghoon Kim, Ji Sung Lee, Choong Guen Chee, Youngjune Kim, Sang Il Choi
Head & Neck.2020; 42(10): 3041. CrossRef
The Milan system for reporting salivary gland cytopathology: The clinical impact so far. Considerations from theory to practice
Esther Diana Rossi, William C. Faquin
Cytopathology.2020; 31(3): 181. CrossRef
The role of core needle biopsy in parotid glands lesions with inconclusive fine needle aspiration
Farrokh Heidari, Firouzeh Heidari, Benyamin Rahmaty, Neda Jafari, Kayvan Aghazadeh, Saeed Sohrabpour, Ebrahim Karimi
American Journal of Otolaryngology.2020; 41(6): 102718. CrossRef
Role of Fine Needle Aspiration Cytology in the Diagnosis of Parotid Gland Tumors: Analysis of 193 Cases
Rahim Dhanani, Haissan Iftikhar, Muhammad Sohail Awan, Nida Zahid, Sehrish Nizar Ali Momin
International Archives of Otorhinolaryngology.2020; 24(04): e508. CrossRef
Cytohistological correlation of salivary gland tumours with emphasis on Milan system for reporting: A novel step towards internal quality assurance
Anandraj Vaithy.K, ATM Venkat Raghava, E S Keerthika Sri, K R Umadevi
IP Archives of Cytology and Histopathology Research.2020; 5(4): 283. CrossRef
Diagnosing Recently Defined and Uncommon Salivary Gland Lesions in Limited Cellularity Specimens: Cytomorphology and Ancillary Studies
Esther Diana Rossi, Zubair Baloch, William Faquin, Liron Pantanowitz
AJSP: Reviews and Reports.2020; 25(5): 210. CrossRef
Peripheral T Cell Lymphoma of Parotid Gland: A Diagnostic Challenge
J. G. Aishwarya, Satish Nair, C. N. Patil, Swarna Shivakumar, N. Shrivalli, Ashish Shah
Indian Journal of Otolaryngology and Head & Neck Surgery.2019; 71(S1): 533. CrossRef
Potential utility of core needle biopsy in the diagnosis of IgG4-related dacryoadenitis and sialadenitis
Kenichi Takano, Tsuyoshi Okuni, Keisuke Yamamoto, Ryuta Kamekura, Ryoto Yajima, Motohisa Yamamoto, Hiroki Takahashi, Tetsuo Himi
Modern Rheumatology.2019; 29(2): 393. CrossRef
Retrospective assessment of the effectiveness of the Milan system for reporting salivary gland cytology: A systematic review and meta‐analysis of published literature
Sahar J Farahani, Zubair Baloch
Diagnostic Cytopathology.2019; 47(2): 67. CrossRef
Values of fine‐needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution
Manabu Suzuki, Ryo Kawata, Masaaki Higashino, Shuji Nishikawa, Tetsuya Terada, Shin‐Ichi Haginomori, Yoshitaka Kurisu, Yoshinobu Hirose
Head & Neck.2019; 41(2): 358. CrossRef
Positive Surgical Margins in Submandibular Malignancies: Facility and Practice Variation
Liliya Benchetrit, Elliot Morse, Benjamin L. Judson, Saral Mehra
Otolaryngology–Head and Neck Surgery.2019; 161(4): 620. CrossRef
The growth rate and the positive prediction of needle biopsy of clinically diagnosed Warthin’s tumor
Jungirl Seok, Woo-Jin Jeong, Soon-Hyun Ahn, Young Ho Jung
European Archives of Oto-Rhino-Laryngology.2019; 276(7): 2091. CrossRef
The Difference in the Clinical Features Between Carcinoma ex Pleomorphic Adenoma and Pleomorphic Adenoma
Jungirl Seok, Se Jin Hyun, Woo-Jin Jeong, Soon-Hyun Ahn, Hyojin Kim, Young Ho Jung
Ear, Nose & Throat Journal.2019; 98(8): 504. CrossRef
Fine‐needle aspiration cytology and radiological imaging in parotid gland tumours: Our experience in 103 patients
Clare Perkins, Edward Toll, Philip Reece
Clinical Otolaryngology.2019; 44(6): 1124. CrossRef
Ultrasound‐guided core needle biopsy in salivary glands: A meta‐analysis
Hee Joon Kim, Jong Seung Kim
The Laryngoscope.2018; 128(1): 118. CrossRef
Accuracy and effectiveness of ultrasound-guided core-needle biopsy in the diagnosis of focal lesions in the salivary glands
Jose Luis del Cura, Gloria Coronado, Rosa Zabala, Igone Korta, Ignacio López
European Radiology.2018; 28(7): 2934. CrossRef
The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC): an ASC-IAC–sponsored system for reporting salivary gland fine-needle aspiration
Esther Diana Rossi, Zubair Baloch, Marc Pusztaszeri, William C. Faquin
Journal of the American Society of Cytopathology.2018; 7(3): 111. CrossRef
Routine and Advanced Ultrasound of Major Salivary Glands
Kunwar Suryaveer Singh Bhatia, Yuk-Ling Dai
Neuroimaging Clinics of North America.2018; 28(2): 273. CrossRef
The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC): An ASC-IAC-Sponsored System for Reporting Salivary Gland Fine-Needle Aspiration
Esther Diana Rossi, Zubair W. Baloch, Marc Pusztaszeri, William C. Faquin
Acta Cytologica.2018; 62(3): 157. CrossRef
Evaluation and diagnosis of salivary gland neoplasms
Erica Jackson Mayland, Anna M. Pou
Operative Techniques in Otolaryngology-Head and Neck Surgery.2018; 29(3): 129. CrossRef
Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
Lana M. Chahine, Thomas G. Beach, Nicholas Seedorff, Chelsea Caspell-Garcia, Christopher S. Coffey, Michael Brumm, Charles H. Adler, Geidy E. Serrano, Carly Linder, Sherri Mosovsky, Tatiana Foroud, Holly Riss, Dixie Ecklund, John Seibyl, Danna Jennings, V
Journal of Parkinson's Disease.2018; 8(4): 517. CrossRef
Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy?
Peter Zbären, Asterios Triantafyllou, Kenneth O. Devaney, Vincent Vander Poorten, Henrik Hellquist, Alessandra Rinaldo, Alfio Ferlito
European Archives of Oto-Rhino-Laryngology.2018; 275(11): 2609. CrossRef
A comparison study of the reporting systems for salivary gland fine needle aspirations: Are they really different?
Diana Montezuma, Sule Canberk, Ozlem Aydın, Mehmet Polat Dermirhas, André F. Vieira, Süha Goksel, Ümit İnce, Fernando Schmitt
Diagnostic Cytopathology.2018; 46(10): 859. CrossRef
Pediatric salivary gland carcinomas: Diagnostic and therapeutic management
Céleste Rebours, Vincent Couloigner, Louise Galmiche, Odile Casiraghi, Cécile Badoual, Sabah Boudjemaa, Anthony Chauvin, Monique Elmaleh, Brice Fresneau, Sylvie Fasola, Erea‐Noël Garabédian, Thierry Van Den Abeele, Daniel Orbach
The Laryngoscope.2017; 127(1): 140. CrossRef
Agreement between rapid on‐site evaluation and the final cytological diagnosis of salivary gland specimens
S. Wangsiricharoen, S. Lekawanvijit, S. Rangdaeng
Cytopathology.2017; 28(4): 321. CrossRef
Mesenchymal neoplasms of the head and neck: a cytopathologic analysis on fine needle aspiration
James Lee, Samia Kazmi, Christopher J. VandenBussche, Syed Z. Ali
Journal of the American Society of Cytopathology.2017; 6(3): 105. CrossRef
Clinical Results of Surgical Treatment in Parotid Tumors
Ahmet Kara
Journal of Otolaryngology-ENT Research.2017;[Epub] CrossRef
Parotid gland metastases of distant primary tumours: A diagnostic challenge
Achim M. Franzen, Thomas Günzel, Anja Lieder
Auris Nasus Larynx.2016; 43(2): 187. CrossRef
Modern Radiology in the Management of Head and Neck Cancer
G.J.C. Burkill, R.M. Evans, V.V. Raman, S.E.J. Connor
Clinical Oncology.2016; 28(7): 440. CrossRef
Fine‐needle aspiration and core needle biopsy: An update on 2 common minimally invasive tissue sampling modalities
Paul A. VanderLaan
Cancer Cytopathology.2016; 124(12): 862. CrossRef
Staging and follow-up of high-grade malignant salivary gland tumours: The role of traditional versus functional imaging approaches – A review
Nicole Freling, Flavio Crippa, Roberto Maroldi
Oral Oncology.2016; 60: 157. CrossRef
Biopsy of parotid masses: Review of current techniques
Sananda Haldar, Joseph D Sinnott, Kemal M Tekeli, Samuel S Turner, David C Howlett
World Journal of Radiology.2016; 8(5): 501. CrossRef
Review on the applications of ultrasonography in dentomaxillofacial region
Şehrazat Evirgen
World Journal of Radiology.2016; 8(1): 50. CrossRef
Comprehensive Cytomorphologic Analysis of Pulmonary Adenoid Cystic Carcinoma: Comparison to Small Cell Carcinoma and Non-pulmonary Adenoid Cystic Carcinoma
Seokhwi Kim, Jinah Chu, Hojoong Kim, Joungho Han
Journal of Pathology and Translational Medicine.2015; 49(6): 511. CrossRef

Case Studies

Oncocytic Lipoadenoma: A Rare Case of Parotid Gland Tumor and Review of the Literature: Chen-lin Chi, Tseng-tong Kuo, Li-yu Lee; J Pathol Transl Med. 2015;49(2):144-147. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2014.02.10

8,497 View
59 Download
7 Web of Science
7 Crossref

Abstract PDF

Oncocytic lipoadenoma is a rare tumor, with only 18 cases having been reported since the first in 1998. We encountered a case of oncocytic lipoadenoma presenting as a slowly growing parotid mass in a 71-year-old man. This tumor is characteristically comprised of a mixture of oncocytes and adipocytes. The present case is one of five reported cases of oncocytic lipoadenoma showing sebaceous differentiation. The results of immunohistochemical study with DOG1 antibody supported the origination of this tumor in the striated duct.

Citations

Citations to this article as recorded by

Oncocytic sialolipoma of parotid gland: Case report and literature review
VenuPatel Sureja, KoyyeRavindranath Tagore
Indian Journal of Pathology and Microbiology.2023; 66(3): 591. CrossRef
Complex Component of Oncocytic and Non-Oncocytic Lipoadenomas in the Parotid Gland: A Case Report
Fuyuki Sato, Takashi Nakajima, Takashi Sugino
Diagnostics.2021; 11(8): 1478. CrossRef
Oncocyitic lipoadenoma of the parotid gland
Renato PIANTANIDA, Alberto CARANTI, Adele CHIESA, Jessica BARIZZI, Ulrike PERRIARD, Filippo BARUCCA, Antonio PELLANDA
Otorinolaringologia.2021;[Epub] CrossRef
A case of oncocytic lipoadenoma of the submandibular gland and its diagnostic cytology challenges
Khaled A. Murshed, Ammar Khalafalla, Belal Alani, Hanan Farghaly, Moustafa Alkhalil
Diagnostic Cytopathology.2020; 48(4): 364. CrossRef
An extremely rare case of giant oncocytic adenolipoma of the parotid gland
Dipesh Shakya, Ajit Nepal
Clinical Case Reports.2020; 8(12): 2390. CrossRef
A rare cause of primary hyperparathyroidism: Parathyroid lipoadenoma
Sabri Özden, Servet Güreşci, Barış Saylam, Gül Dağlar
Auris Nasus Larynx.2018; 45(6): 1245. CrossRef
Oncocytic osteolipoadenoma of the submandibular gland
Domenico Corradi, Rodolfo Monaco, Giulia D'Angelo, Paola Bini, Teore Ferri, Enrico M Silini
Histopathology.2016; 69(1): 148. CrossRef

Fallopian Metaplastic Papillary Tumour: An Atypical Transdifferentiation of the Tubal Epithelium?: Miguel Fdo. Salazar, Isaías Estrada Moscoso, Lorena Troncoso Vázquez, Nubia Leticia López García, Paola Andrea Escalante Abril; J Pathol Transl Med. 2015;49(2):148-155. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2014.10.15

8,256 View
56 Download
2 Web of Science
2 Crossref

Abstract PDF

A metaplastic papillary tumor of the Fallopian tube is an extremely uncommon condition, with odd and confusing features that make it difficult to categorize as benign or borderline. Here, we summarize all the published cases to date and document the case of a 41-year-old woman diagnosed with this alteration after her last childbirth and ensuing tubal ligation. One of the tubes was bulky and filled with a caramel-like substance encircling a blurry spot. Light microscopy detailed a slender stalk covered by eosinophilic, columnar plump cells, showing atypical nuclei and focal budding. Mitotic figures were absent. The immunohistochemistry panel was positive for pan-cytokeratin, epithelial membrane antigen, cyclin D1, and hormone receptors. Additionally, a proliferation index of less than 5% was rated using Ki-67. The true nature of this tumor (reactive vs neoplastic) is uncertain. Nonetheless, its association with pregnancy suggests an adaptive change, likely similar to the atypical transdifferentiation proposed for Arias-Stella reaction.

Citations

Citations to this article as recorded by

Fallopian tube papilloma: An unusual cause of infertility
Shashank Mishra, Prerna Guleria
Indian Journal of Pathology and Microbiology.2021; 64(3): 608. CrossRef
Metaplastic papillary tumour of the fallopian tube, a rare entity, analysed by next‐generation sequencing
Sandra Sunitsch, Julia Reisinger, Luca Abete, Karl Kashofer, Peter Regitnig
Histopathology.2020; 76(6): 923. CrossRef

Brief Case Reports

Angiomyomatous Hamartoma of Popliteal Lymph Node: An Unusual Entity: Asit Ranjan Mridha, Richa Ranjan, Prateek Kinra, Ruma Ray, Shah Alam Khan, Gamanagatti Shivanand; J Pathol Transl Med. 2015;49(2):156-158. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2013.08.08

10,924 View
82 Download
6 Web of Science
5 Crossref

PDF

Citations

Citations to this article as recorded by

Angiomyomatous hamartoma of the inguinal lymph nodes with localized lymphedema presenting as a soft subcutaneous mass
Ryoma Honda, Kazuyasu Fujii, Masanori Nakajo, Takuro Kanekura
JAAD Case Reports.2022; 27: 117. CrossRef
Angiomyomatous hamartoma in a postauricular lymph node: A rare entity masquerading as a cyst
Mardeen S. Karim, Courtney J. Ensslin, Margaret L. Dowd, Faramarz H. Samie
JAAD Case Reports.2021; 7: 131. CrossRef
Cryoablation of an Inguinal Angiomyomatous Hamartoma: A Case Report
Christopher A. Woolley, Rodney A. Gabriel, Engy T. Said, Jeffrey Chen
A&A Practice.2021; 15(7): e01492. CrossRef
Intranodal Angiomyomatous Hamartoma in a Cynomolgus Monkey
Catherine Thirion-Delalande, Frédéric Gervais, Bernard Palate, Roy Forster, André Almeida Schenka
Toxicologic Pathology.2019; 47(2): 190. CrossRef
Painful Inguinal Angiomyomatous Hamartoma Responsive to Conservative Pain Management: A Case Report
Christopher A. Woolley, Jessica Oswald, Jeffrey Chen
A&A Practice.2019; 13(10): 373. CrossRef

Focal Hematopoietic Hyperplasia of Rib: A Rare Pseudotumor and Review of Literature: Maneesh Vijay, Asit Ranjan Mridha, Ruma Ray, Prateek Kinra, Biplab Mishra, H. S. Chandrashekhar; J Pathol Transl Med. 2015;49(2):159-162. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2013.10.02

8,920 View
59 Download
2 Web of Science
4 Crossref

PDF

Citations

Citations to this article as recorded by

Bone abnormalities in the middle Anisian marine sauropsids from Winterswijk
Dawid Surmik, Tomasz Szczygielski, Justyna Słowiak‐Morkovina, Martin Sander, Bruce Rothschild, Piotr Duda, Nicole Klein
Journal of Morphology.2023;[Epub] CrossRef
Focal hematopoietic hyperplasia of the rib—A form of pseudo-tumor. Case report and review of articles
Reza Mollahosseini, Paniz Motaghi, Alireza Dastmalchi, Hanieh Zahm
International Journal of Surgery Case Reports.2020; 66: 228. CrossRef
A rare case of the recurrent surgery for cribriform-morular variant of papillary thyroid carcinoma
Keisuke Enomoto, Shunji Tamagawa, Naoko Kumashiro, Kenji Warigaya, Saori Takeda, Mehmet Gunduz, Shin-ichi Murata, Muneki Hotomi
International Journal of Surgery Case Reports.2019;[Epub] CrossRef
Cranial Focal Nodular Haematopoietic Hyperplasia: A case report and literature review
Kamal Makram Yakoub, Athanasios Zisakis, Ismail Ughratdar
Journal of Clinical Neuroscience.2018; 53: 244. CrossRef

Serous Cystadenoma and Fibrothecoma: A Rare Combination in Collision Tumor of Ovary with Pseudo-Meigs Syndrome: Shirish S. Chandanwale, Sukanya S. Pal, Harsh B. Kumar, Amit B. Sammi; J Pathol Transl Med. 2015;49(2):163-166. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2013.11.25

10,263 View
66 Download
8 Web of Science
8 Crossref

PDF

Citations

Citations to this article as recorded by

Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma
Xue Fan, Haoyue Hu, Yang Liu, Songtao Tan, Meng Xie, Fang Zhang
Frontiers in Medicine.2023;[Epub] CrossRef
A case report of bilateral benign Ovarian Fibrothecoma coincidental with ascites: an unconventional co-occurrence
Raied Mohamad, Omar Al Laham, Reham Albrijawy, Mostafa Sallom, Alhasan Merhij, Mohammad Almousa
Annals of Medicine & Surgery.2023; 85(7): 3739. CrossRef
Ultrasound Findings and O‐RADS Malignancy Risk Stratification of Ovarian Collision Tumors
Yuyang Guo, Shan Zhou, Baihua Zhao, Lieming Wen, Minghui Liu
Journal of Ultrasound in Medicine.2022; 41(9): 2325. CrossRef
A Rare Case of Collision Tumours of the Ovary: An Ovarian Serous Cystadenoma Coexisting with Fibrothecoma
Michele Mongelli, Erica Silvestris, Vera Loizzi, Gennaro Cormio, Gerardo Cazzato, Francesca Arezzo
Diagnostics.2022; 12(11): 2840. CrossRef
A Rare Case of Pseudo-Meigs' Syndrome With Ovarian Metastasis Presenting as Meigs' Syndrome
Nimit Dalal, Pal Satyajit Singh Athwal, Biswaraj Tharu, Lakshmi Saravanan, Hassan Mansour
Cureus.2020;[Epub] CrossRef
Collision Tumors in Ovary: Case Series and Literature Review
Borges A, Loddo A, Martins A, Peiretti M, Fanni D, Djokovic D
Journal of Surgical Oncology.2019; : 1. CrossRef
Combined ovarian serous cystadenoma and thecoma
Mudiwa Muronda, Peter Russell
Pathology.2018; 50(3): 367. CrossRef
Collision Signet-Ring Stromal Tumor and Steroid Cell Tumor of the Ovary: Report of the First Case
Stephanie M. McGregor, J. Kenneth Schoolmeester, Ricardo R. Lastra
International Journal of Gynecological Pathology.2017; 36(3): 261. CrossRef

Unicystic Granulosa Cell Tumor: Nalli R. Sumitra Devi, Sathya Lakshmi Ramu, Arun Prabhakaran, Deepa Devi Govindaswamy; J Pathol Transl Med. 2015;49(2):167-170. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2014.04.02

8,270 View
65 Download

PDF

Retiform Hemangioendothelioma of the Neck: Chin-Lung Kuo, Paul Chih-Hsueh Chen, Wing-Yin Li, Pen-Yuan Chu; J Pathol Transl Med. 2015;49(2):171-173. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2013.10.14

11,691 View
77 Download
5 Web of Science
1 Crossref

PDF

Citations

Citations to this article as recorded by

Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature
Aileen Grace P. Arriola, Laura A. Taylor, Eseosa Asemota, Markus D. Boos, David E. Elder, Kristy L. Weber, Robert G. Micheletti, Paul J. Zhang
Journal of Cutaneous Pathology.2017; 44(1): 98. CrossRef

Metastatic Endobronchial Adenocarcinoma from the Uterine Cervix Verified by Human Papillomavirus Genotyping: Jisup Kim, Sungsoo Lee, Heae Surng Park; J Pathol Transl Med. 2015;49(2):174-176. Published online March 12, 2015; DOI: https://doi.org/10.4132/jptm.2015.02.10

9,070 View
53 Download

PDF

First
Prev
Page of 2
Next
Last

Previous issues