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Case Study
Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report
Hyekyung Lee, Dongwook Kang, Heejin Kim, Byungsun Cho, Jeho Jang
J Pathol Transl Med. 2017;51(3):320-324.   Published online April 4, 2017
DOI: https://doi.org/10.4132/jptm.2016.09.07
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AbstractAbstract PDF
Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.

Citations

Citations to this article as recorded by  
  • Eosinophilic Myenteric Ganglionitis Presenting as Sigmoid Volvulus: A Brief Report
    Alyson Kim, Jeffrey L. Roberson, Lillias H. Maguire, Bo Jian, Nicole M. Saur
    The American Surgeon™.2023; 89(11): 5021.     CrossRef
  • Histological characteristics of eosinophilic myenteric ganglionitis: an under-recognised cause of chronic intestinal pseudo-obstruction
    Yoichi Akazawa, Takuo Hayashi, Tsuyoshi Saito, Koichiro Niwa, Hirohiko Kamiyama, Noriko Sasahara, Kazuhiro Sakamoto, Akihito Nagahara, Takashi Yao
    Virchows Archiv.2019; 474(3): 395.     CrossRef
  • Colonic Pseudo-obstruction With Transition Zone: A Peculiar Eastern Severe Dysmotility
    Eun Mi Song, Jong Wook Kim, Sun-Ho Lee, Kiju Chang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Wook Jung, Byong Duk Ye, Jeong-Sik Byeon, Suk-Kyun Yang, Hyo Jeong Lee, Chang Sik Yu, Chan Wook Kim, Seong Ho Park, Jihun Kim, Seung-Jae Myung
    Journal of Neurogastroenterology and Motility.2019; 25(1): 137.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine