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1 "Hybrid tumor"
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Case Report
A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma
Ji Young Park, Nam Jo Park, Sang Pyo Kim, Kun Young Kwon, Sang Sook Lee
Korean J Pathol. 2012;46(1):75-78.   Published online February 23, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.1.75
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  • 14 Crossref
AbstractAbstract PDF

Perineuriomas are composed of differentiated perineurial cells. Perineuriomas have been recently recognized by the immunoreactivity for epithelial membrane antigen (EMA). Microscopically, perineuriomas show proliferation of spindle cells with wavy nuclei and delicate elongated bipolar cytoplasmic processes. The tumor cells are usually negative for the S-100 protein. Ultrastructurally, perineurial cells reveal slender, nontapered processes containing pinocytic vesicles and discontinuous basal lamina. Interestingly, hybrid tumors of benign peripheral nerve sheath tumor (PNST) have been recently reported by using immunohistochemical and ultrastructural investigations. Herein, we report a case of soft tissue perineurioma arising in the skin of a 56-year-old female; another case of a hybrid tumor of perineurioma and schwannoma in the posterior mediastinum occurred in a 53-year-old male, which is the first case of the hybrid PNST tumor reported in Korea.

Citations

Citations to this article as recorded by  
  • Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations
    Michael A den Bakker, Annikka Weissferdt
    Histopathology.2024; 84(1): 238.     CrossRef
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    Karina A. Lenartowicz, Dileep D. Monie, Kimberly K. Amrami, Christopher J. Klein, Caterina Giannini, Robert J. Spinner
    Acta Neurochirurgica.2022; 165(4): 935.     CrossRef
  • Hybrid Schwannoma/Perineurioma: Morphologic Variations and Genetic Profiles
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  • Mesenchymal Tumors of the Mediastinum: An Update on Diagnostic Approach
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  • A Rare Perineurioma/Granular Cell Tumor Hybrid Peripheral Nerve Sheath Tumor
    Koorosh Haghayeghi, Gladys Telang, Sonja Chen, Jack Bevivino, Shamlal Mangray, Yiang Hui, Leslie Robinson-Bostom
    The American Journal of Dermatopathology.2020; 42(10): 762.     CrossRef
  • Hybrid peripheral nerve sheath tumors
    Emine KILIÇ BAĞIR, Arbil AÇIKALIN, Gülfiliz GÖNLÜŞEN, Suzan ZORLUDEMİR, Mehmet Ali DEVECİ
    Cukurova Medical Journal.2019; 44(3): 804.     CrossRef
  • Primary intraosseous hybrid epithelioid schwannoma/perineurioma in the proximal tibia: a case report of benign hybrid neoplasm with local hypercellularity
    Yuejiao Lang, Dawei Liu, Pei Xiang, Jilin Wang, Yang Li
    Diagnostic Pathology.2019;[Epub]     CrossRef
  • Hybrid peripheral nerve sheath tumors: report of five cases and detailed review of literature
    Nasir Ud Din, Zubair Ahmad, Jamshid Abdul-Ghafar, Rashida Ahmed
    BMC Cancer.2017;[Epub]     CrossRef
  • Primary intraosseous hybrid nerve sheath tumor of femur: A hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture
    Louis Tsun Cheung Chow
    Pathology - Research and Practice.2015; 211(5): 409.     CrossRef
  • Mesenchymal tumours of the mediastinum—part II
    Michael A. den Bakker, Alexander Marx, Kiyoshi Mukai, Philipp Ströbel
    Virchows Archiv.2015; 467(5): 501.     CrossRef
  • Primary pleural hybrid cellular schwannoma/perineurioma: A case report
    Danny Soria-Céspedes, Carlos Robles-Vidal, Arturo Gómez-González, Rosalinda Peñaloza-Ramírez, Carlos Ortiz-Hidalgo
    Respiratory Investigation.2014; 52(4): 269.     CrossRef
  • Hybrid peripheral nerve sheath tumour with intermingled perineuriomatous and schwannomatous areas reflected in skin ultrasonography image
    H. Saeki, K. Ito, Y. Nobeyama, T. Ishiji, M. Fukunaga, H. Nakagawa
    Clinical and Experimental Dermatology.2014; 39(6): 747.     CrossRef
  • Périneuriome extraneural des tissus mous localisé au nez
    A. Zaouak, R. Benmously, M. Belhadj Salah, W. Koubaa, A. Debbiche, I. Mokhtar
    Annales de Dermatologie et de Vénéréologie.2013; 140(8-9): 540.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine