| Home | E-Submission | Sitemap | Contact Us
top_img
JPTM > Ahead-of Print

doi: https://doi.org/10.4132/jptm.2016.09.16    [Epub ahead of print]
Perivascular Epithelioid Cell Tumor in the Stomach
Sun Ah Shin, Jiwoon Choi, Kyung Chul Moon, Woo Ho Kim
Department of Pathology, Seoul National University Hospital, Seoul, Korea
Corresponding Author: Woo Ho Kim ,Tel: +82-2-740-8269, Fax: +82-2-765-5600, Email: woohokim@snu.ac.kr
Received: August 15, 2016;  Accepted: September 16, 2016.  Published online: April 4, 2017.
ABSTRACT
Perivascular epithelioid cell tumors or PEComas can arise in any location in the body. However, a limited number of cases of gastric PEComa have been reported. We present two cases of gastric PEComas. The first case involved a 62-year-old woman who presented with a 4.2 cm gastric subepithelial mass in the prepyloric antrum, and the second case involved a 67-year-old man with a 5.0 cm mass slightly below the gastroesophageal junction. Microscopic examination revealed that both tumors were composed of perivascular epithelioid cells that were immunoreactive for melanocytic and smooth muscle markers. Prior to surgery, the clinical impression of both tumors was gastrointestinal stromal tumor (GIST), and the second case was erroneously diagnosed as GIST even after microscopic examination. Although gastric PEComa is a very rare neoplasm, it should be considered in the differential diagnosis of gastric submucosal lesions.
Key Words: Perivascular epithelioid cell neoplasms; Stomach neoplasms; HMB-45 protein, human; MART-1 antigen; Gastrointestinal stromal tumors