Fig. 1Our classical technique: one sample is taken from each of the fundus, body, and neck/cystic duct regions and all samples are all placed in one cassette.
Fig. 2The longitudinal sampling technique: a sample taken from the neck region and another sample taken lengthwise from the fundus toward the neck (the latter rolled with the "swiss-roll" method) are placed together in one cassette.
Fig. 3In some specimens, mucosal yellow flecks are seen and these flecks lay side by side and formed linear striations which run parallel to the long axis of the specimen.
Table 1.The clinicopathologic data and the p-value of the two groups
|
First group (classical technique) |
Second group (longitudinal sampling technique) |
p-value |
Macroscopic features |
|
|
|
Length of gallbladders (cm) |
8.25 ± 4.11 |
7.56 ± 1.72 |
.006 |
Diameter of gallbladders (cm) |
3.13 ± 1.60 |
2.78 ± 0.85 |
.001 |
Length of sample taken (mm) |
34.86 ± 11.03 |
40.70 ± 12.11 |
< .0001 |
Wall-thickness of gallbladders (cm) |
0.43 ± 0.32 |
0.41 ± 0.28 |
> .05 |
POMa (%) |
72.01 ± 24.77 |
67.66 ± 34.05 |
> .05 |
No. of cases with cholelithiasis |
224 (82.1) |
281 (83.9) |
> .05 |
No. of cases with IISOLb
|
12 (4.4) |
16 (4.8) |
> .05 |
No. of cases with papillary hyperplasia |
43 (15.8) |
37 (11) |
> .05 |
Microscopic features |
|
|
|
Acute inflammatory cells |
33 (12.1) |
48 (14.3) |
< .0001 |
Chronic inflammatory cells |
270 (87.9) |
308 (91.9) |
< .0001 |
Cholesterolosis |
72 (26.4) |
58 (17.3) |
.001 |
Pyloric metaplasia |
36 (13.2) |
69 (20.6) |
.001 |
Intestinal metaplasia |
0 |
9 (2.7) |
.001 |
Low grade displasia |
1 (0.4) |
13 (3.9) |
.007 |
Invasive carcinoma |
0 |
2 (0.6) |
.007 |