Fig. 1Positron emission tomography-computed tomography shows a right inguinal mass (27 mm) with low metabolism (arrow).
Fig. 2The tumor is well-circumscribed and showed numerous papillary nodular protrusions into a central cystic cavity (3.5×2.5 cm) (A). Eccentrically, a normal breast tissue (B) is present.
Fig. 3The microscopic findings show a central elongated cyst with intraluminal projections (A), which is composed of hyperplastic epithelium lined stroma (B). Stromal cells have no mitosis, low-to-moderated cellularity, and mild cytoplasm atypia (C). The lining epithelial cells are diffusely and strongly positive for estrogen receptor. Myoepithelial cells are nonreactive (immunohistochemistry for estrogen receptor [red] and smooth muscle actin [brown]) (D).
Fig. 4In the periphery of the mass, normal breast tissue is identified.
Table 1.Summary of the reported cases of ectopic phyllodes tumor
Case No. |
Age (yr) |
Location |
Size (cm) |
Histology |
Treatment |
Reference |
1 |
20 |
Labium majora |
3.0 × 4.0 |
Benign |
Excision |
Tbakhi et al. [9] |
2 |
39 |
Labium majus |
1.4 × 2.0 |
Benign |
Excision |
Tresserra et al. [10] |
3 |
17 |
Labium majus and minus |
1.6 × 1.2 |
Benign |
Excision |
Tresserra et al. [10] |
4 |
34 |
Labium majus |
6.0 × 4.0 |
Benign |
Excision |
Chulia et al. [11] |
5 |
31 |
Axilla |
1.7 × 1.6 |
Benign |
Excision |
Oshida et al. [3] |
6 |
45 |
Axilla |
3 × 2 |
Low-grade |
Wide excision |
Saleh and Klein [12] |