- Immunohistochemical Identification of Pneumocystis jirovecii in Liquid-based Cytology of Bronchoalveolar Lavage: Nine Cases Report.
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Jeong Hyeon Lee, Ji Young Lee, Mi Ran Shin, Hyeong Kee Ahn, Chul Whan Kim, Insun Kim
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Korean J Pathol. 2011;45(1):115-118.
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DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.1.115
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- Pneumocystis pneumonia (PCP) is caused by the yeast-like fungus Pneumocystis jirovecii, which is specific to humans.
PCP could be a source of opportunistic infection in adults that are immunosuppressed and children with prematurity or malnutrition. The diagnosis should be confirmed by identification of the causative organism, by analysis of the sputum, a bronchoalveolar lavage or a tissue biopsy. In both histologic and cytologic specimens, the cysts are contained within frothy exudates, which form aggregated clumps. The cysts often collapse forming crescent-shaped bodies that resemble ping-pong balls. We recently diagnosed nine cases of PCP using an immunohistochemical stain for Pneumocystis.
The patients consisted of five human immunodeficiency virus positive individuals, two renal transplant recipients, and two patients with a malignant disease. All nine patients were infected with P. jirovecii, which was positive for monoclonal antibody 3F6. In conclusion, the immunohistochemical stain used in this report is a new technique for the detection of P. jirovecii infection.
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Citations
Citations to this article as recorded by  - Metabolic Changes in Serum Metabolome of Beagle Dogs Fed Black Ginseng
Dahye Yoon, Ye Jin Kim, Wan Kyu Lee, Bo Ram Choi, Seon Min Oh, Young Seob Lee, Jae Kwang Kim, Dae Young Lee
Metabolites.2020; 10(12): 517. CrossRef - Effects of Red or Black Ginseng Extract in a Rat Model of Inflammatory Temporomandibular Joint Pain
Hyeon-Jeong Lee, Yun-Kyung Kim, Ja-Hyeong Choi, Jung-Hwa Lee, Hye-Jin Kim, Mi-Gyung Seong, Min-Kyung Lee
Journal of Dental Hygiene Science.2017; 17(1): 65. CrossRef - Value of Bronchoalveolar Lavage Fluid Cytology in the Diagnosis ofPneumocystis jiroveciiPneumonia: A Review of 30 Cases
Ji-Youn Sung, Joungho Han, Young Lyun Oh, Gee Young Suh, Kyeongman Jeon, Taeeun Kim
Tuberculosis and Respiratory Diseases.2011; 71(5): 322. CrossRef
- Malignant Glomus Tumors of the Stomach: A Report of 2 Cases with Multiple Metastases.
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Hyunjoo Lee, Yoon Seok Choi, Sang Cheul Oh, Jong Jae Park, Chul Whan Kim, Han Kyeom Kim, Insun Kim
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Korean J Pathol. 2009;43(4):358-363.
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DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.4.358
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3,223
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- Glomus tumors are mesenchymal neoplasms usually developing in the dermis or subcutis of the extremities. The majority of glomus tumors are entirely benign, and malignant glomus tumors are very rare, especially those arising in the visceral organs. Here, we are presenting two cases of malignant glomus tumor, initially diagnosed in the stomach by endoscopic biopsy. Case 1 was found in the stomach, right kidney, brain and humerus of a 65-year-old woman, and Case 2 in the stomach and liver of a 63-year-old man.
Histologically, the tumor was composed of solid sheets and nests of round and short-spindle shaped tumor cells with vesicular nucleus and prominent nucleolus. The tumor cells were closely admixed with blood vessels of varying size.
Immunohistochemically, the tumor cells showed diffuse and strong positive staining for smooth muscle actin and paranuclear, dot-like staining for synaptophysin, but negative for desmin, c-kit, CD34 and S-100 protein. These two are rare cases of a malignant glomus tumor with widespread metastases.
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Citations
Citations to this article as recorded by - Clinicopathologic features of gastric glomus tumor: A report of 15 cases and literature review
Minying Deng, Rongkui Luo, Jie Huang, Yuanlong Luo, Qi Song, Huaiyu Liang, Chen Xu, Wei Yuan, Yingyong Hou
Pathology and Oncology Research.2023;[Epub] CrossRef - Gastric Glomus Tumor: A Clinicopathologic and Immunohistochemical Study of 21 Cases
Jun Lin, Juan Shen, Hao Yue, Qiongqiong Li, Yuqing Cheng, Mengyun Zhou
BioMed Research International.2020; 2020: 1. CrossRef - Malignant glomus tumor of the gastric antrum with hepatic metastases: a case report and literature review
Adina A. Bodolan, Rebecca Wilcox, Michelle X. Yang
Human Pathology: Case Reports.2018; 14: 81. CrossRef
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