- Primary Hepatic Neuroblastoma: A Case Report.
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Geunyoung Jung, Jihun Kim
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Korean J Pathol. 2011;45(4):423-427.
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DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.4.423
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 Abstract
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- Neuroblastoma is a malignant tumor of primordial neural crest origin. It usually develops along the sympathetic nervous system, such as the adrenal glands or paramedian sympathetic chain and metastasizes to the liver most frequently. However, a primary hepatic neuroblastoma has not been reported yet. Here, we report a case of 29-year-old woman who presented with a solitary hepatic mass. Grossly, the mass was large, creamy, rubbery firm, and showed focal hemorrhage and central cavitation. Microscopically, the tumor cells were arranged in small nests of spindle to ovoid cells with abundant neuropil. The neuroblastic nature of the tumor was confirmed by immunohistochemistry and electron microscopy. No extrahepatic mass was found, despite a thorough systemic survey such as chest and abdominopelvic computed tomography (CT) scans and a whole body positron emission tomography-CT study. To the best of our knowledge, this is the first report of a bona fide primary hepatic neuroblastoma.
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Citations
Citations to this article as recorded by  - Primary hepatic neuroblastoma in a 19-month-old child: A case report
Jovana Dimić, Dejan Skorić, Aleksandar Sretenović, Slaviša Đuričić
Medicinska istrazivanja.2022; 55(2): 41. CrossRef - Morphologic Alteration of Metastatic Neuroblastic Tumor in Bone Marrow after Chemotherapy
Go Eun Bae, Yeon-Lim Suh, Ki Woong Sung, Jung-Sun Kim
Korean Journal of Pathology.2013; 47(5): 433. CrossRef
- Dedifferentiated Extraskeletal Myxoid Chondrosarcoma of the Masticator Space: A Case Report.
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Geunyoung Jung, Kyung Ja Cho, Seung Ho Choi, Mi Jung Kim
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Korean J Pathol. 2011;45:S101-S105.
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DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.S1.S101
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3,272
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- We describe a 69-year-old woman who presented with a dedifferentiated extraskeletal myxoid chondrosarcoma arising in the left masticator space. Computed tomography and magnetic resonance imaging revealed a 5 cm sized mass in the left masticator space. Histologically, the tumor consisted of two distinct areas. The less cellular area was a low-grade extraskeletal myxoid chondrosarcoma, composed of strands or cords of uniform spindle cells and abundant myxoid stroma. The more cellular, dedifferentiated area corresponded to a high grade myxofibrosarcoma, consisting of anaplastic tumor cells in myxoid stroma and geographic necrosis. The tumor cells of the former area were positive for S-100 protein, microtubule-associated protein-2 (MAP-2) and class III beta-tubulin, but negative for cytokeratin, smooth muscle actin, and desmin. The tumor cells in the latter, pleomorphic area showed MAP-2 and beta-tubulin immunoreactivity with a high Ki-67 labeling index. Based on its histologic and immunohistochemical features, the tumor was considered a dedifferentiated extraskeletal myxoid chondrosarcoma.
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Citations
Citations to this article as recorded by - Extraskeletal myxoid chondrosarcoma of the parotid gland
NyimiBushabu Fidele, Wu Tianfu, Bing Liu, Yanfang Sun, Zhao Yifang
Annals of Maxillofacial Surgery.2019; 9(2): 439. CrossRef - Myxoid chondrosarcoma of maxilla: A rare case report
Hiralal Ash, Ajoy Kumar Shahi, Kabita Chatterjee, Dipankar Samaddar
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology.2016; 28(3): 273. CrossRef - Maxillo-facial Extraskeletal Myxoid Chondrosarcoma: A Case Report and Discussion
Ratnadeep Ganguly, Abhishek Mukherjee
The Korean Journal of Pathology.2011; 45(6): 639. CrossRef
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