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Gu Hyun Kang 1 Article
Thymofibrolipoma: A Brief Case Report.
Gu Hyun Kang, Joungho Han, Tae Sung Kim, Yong Soo Choi, Sang Won Um
Korean J Pathol. 2010;44(3):338-340.
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AbstractAbstract PDF
Thymofibrolipoma is an extremely rare tumor in the anterior mediastinum, and represents a histologic variant of the usual thymolipoma. Herein, we report a case of thymofibrolipoma in a 9-year-old girl who had a huge mass with fatty attenuation in the right hemithorax on chest computed tomography. She denied any subjective symptoms except mild fever. The surgically resected tumor was ovoid, soft and well-encapsulated, measuring 9.0 x 7.5 x 7.0 cm. The cut surface was light tan in color with yellowish streaks. Microscopically, two distinct areas were admixed in different proportions. One consisted of normal thymic tissue with subinvoluted features and the other was composed of extensive areas of collagenous tissue interspersed in mature adipose tissue. In a high power view, there were thin strands of remnant thymic epithelial cells, separating the pseudolobules. Thymofibrolipoma should be distinguished from other benign or malignant conditions, occurring in the anterior mediastinum, so that unnecessary treatment can be avoided.


Citations to this article as recorded by  
  • Unusual thymoma subtypes
    Michael A. den Bakker
    Diagnostic Histopathology.2023; 29(2): 105.     CrossRef
  • Thymofibrolipoma: a case report and review of the literature
    Ryu Jokoji, Emiko Tomita
    Diagnostic Pathology.2022;[Epub]     CrossRef
  • Thymoangiolipoma: A rare histologic variant of thymolipoma in a patient with myasthenia gravis
    Mohammad Hossein Anbardar, Fatemeh Amirmoezi, Armin Amirian
    Rare Tumors.2020; 12: 203636132097921.     CrossRef

JPTM : Journal of Pathology and Translational Medicine