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Dongwook Kang 2 Articles
Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report
Hyekyung Lee, Dongwook Kang, Heejin Kim, Byungsun Cho, Jeho Jang
J Pathol Transl Med. 2017;51(3):320-324.   Published online April 4, 2017
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  • 2 Citations
AbstractAbstract PDF
Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.


Citations to this article as recorded by  
  • Histological characteristics of eosinophilic myenteric ganglionitis: an under-recognised cause of chronic intestinal pseudo-obstruction
    Yoichi Akazawa, Takuo Hayashi, Tsuyoshi Saito, Koichiro Niwa, Hirohiko Kamiyama, Noriko Sasahara, Kazuhiro Sakamoto, Akihito Nagahara, Takashi Yao
    Virchows Archiv.2019; 474(3): 395.     CrossRef
  • Colonic Pseudo-obstruction With Transition Zone: A Peculiar Eastern Severe Dysmotility
    Eun Mi Song, Jong Wook Kim, Sun-Ho Lee, Kiju Chang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Wook Jung, Byong Duk Ye, Jeong-Sik Byeon, Suk-Kyun Yang, Hyo Jeong Lee, Chang Sik Yu, Chan Wook Kim, Seong Ho Park, Jihun Kim, Seung-Jae Myung
    Journal of Neurogastroenterology and Motility.2019; 25(1): 137.     CrossRef
Nuclear Image Analysis Study of Neuroendocrine Tumors
Meeja Park, Taehwa Baek, Jongho Baek, Hyunjin Son, Dongwook Kang, Jooheon Kim, Hyekyung Lee
Korean J Pathol. 2012;46(1):38-41.   Published online February 23, 2012
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  • 24 Download
  • 2 Citations
AbstractAbstract PDF

There is a subjective disagreement about nuclear chromatin in the field of pathology. Objective values of red, green, and blue (RGB) light intensities for nuclear chromatin can be obtained through a quantitative analysis using digital images.


We examined 10 cases of well differentiated neuroendocrine tumors of the rectum, small cell lung carcinomas, and moderately differentiated squamous cell lung carcinomas respectively. For each case, we selected 30 representative cells and captured typical microscopic findings. Using an image analyzer, we determined the longest nuclear line profiles and obtained graph files and Excel data on RGB light intensities. We assessed the meaningful differences in graph files and Excel data among the three different tumors.


The nucleus of hematoxylin and eosin-stained tumor cells was expressed as a combination of RGB light sources. The highest intensity was from blue, whereas the lowest intensity was from green. According to the graph files, green showed the most noticeable change in the light intensity, which is consistent with the difference in standard deviations.


The change in the light intensity for green has an important implication for differentiating between tumors. Specific features of the nucleus can be expressed in specific values of RGB light intensities.


Citations to this article as recorded by  
  • Difference of the Nuclear Green Light Intensity between Papillary Carcinoma Cells Showing Clear Nuclei and Non-neoplastic Follicular Epithelia in Papillary Thyroid Carcinoma
    Hyekyung Lee, Tae Hwa Baek, Meeja Park, Seung Yun Lee, Hyun Jin Son, Dong Wook Kang, Joo Heon Kim, Soo Young Kim
    Journal of Pathology and Translational Medicine.2016; 50(5): 355.     CrossRef
  • Comparison of diagnostic accuracy between CellprepPlus┬« and ThinPrep┬« liquid-based preparations in effusion cytology
    Yong-Moon Lee, Ji-Yong Hwang, Seung-Myoung Son, Song-Yi Choi, Ho-Chang Lee, Eun-Joong Kim, Hye-Suk Han, Jin young An, Joung-Ho Han, Ok-Jun Lee
    Diagnostic Cytopathology.2014; 42(5): 384.     CrossRef

JPTM : Journal of Pathology and Translational Medicine