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Ki-Seok Jang 1 Article
Castleman's Disease of the Renal Sinus Presenting as a Urothelial Malignancy: A Brief Case Report
Se Min Jang, Hulin Han, Ki-Seok Jang, Young Jin Jun, Tchun Yong Lee, Seung Sam Paik
Korean J Pathol. 2012;46(5):503-506.   Published online October 25, 2012
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AbstractAbstract PDF

Castleman's disease is a rare benign lymphoproliferative disorder that frequently affects lymph nodes of the mediastinal thorax and the neck. It very rarely affects the renal sinus. We report a case of Castleman's disease arising in the renal sinus in a 64-year-old man. The patient visited the hospital with the chief complaint of hematuria. Abdominal computed tomography revealed a homogeneous mass in the sinus of the left kidney, radiologically interpreted as a malignant urothelial tumor. Subsequently, nephroureterectomy was performed, after which microscopic examination of the specimen revealed a diffuse lymphoproliferative lesion with reactive lymphoid follicles of various sizes and prominent plasma cell infiltration of interfollicular spaces, highlighted by immunohistochemical staining for CD138. The lesion was diagnosed as Castleman's disease of the plasma cell type. Although preoperative diagnosis of Castleman's disease is difficult and the incidence is exceedingly rare, it should be considered in the differential diagnosis of renal sinus tumors.


Citations to this article as recorded by  
  • Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma
    Enlong Zhang, Yuan Li, Ning Lang
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Radiologic features of Castleman’s disease involving the renal sinus: A case report and review of the literature
    Xiao-Wan Guo, Xu-Dong Jia, Shan-Shan Shen, Hong Ji, Ying-Min Chen, Qian Du, Shu-Qian Zhang
    World Journal of Clinical Cases.2019; 7(8): 1001.     CrossRef
  • Castleman’s Disease: a Suprarenal Surprise!
    Praveen Sundar, Priyank Bijalwan, Ginil Kumar Pooleri
    Indian Journal of Surgical Oncology.2018; 9(2): 254.     CrossRef

JPTM : Journal of Pathology and Translational Medicine