Journal of Pathology and Translational Medicine

Volume 15(3); September 1981

Etcs

An Application of Wilson-Hilferty's Transformation to Clinical Evaluation of Multitest Values: Chang Soo Chung; Korean J Cytopathol. 1981;15(3):233-237.

945 View
10 Download

Abstract: In one of the recent studies of this author he presented that if the multitest vector of n-components is normal in distribution, the Mahalanobls' squared distance from the mean vector to an observed multitest vector furnishes a good measure for the evaluation of clinical significance of the latter. As the squared distance is a variable which follows chi-squared distribution with n degrees of freedom, in the evaluation one must refer to the quantile table of chi-squared distribution. It gives, however, much inconvenience because the quantiles are dependent on degrees of freedom and the available tables are not detailed enough. One of the ways to exclude this inconvenience is to express the sqaured distance in the equivalent deviate of standard normal distribution. The author investigated the availability in such case of the Wilson-Hilferty transformation of the quantiles of chi-squarrd distribution into normal deviates, and found that as far as the clinical evaluation of the Mahalanbis' squared distance is concerned, the transformation is quite satisfactory even for the small degrees of freedom of chi-squared distribution which are between 2 and 10. The author, therefore, made this report to emphasize the fact that the Wilson-Hilferty's approximation formula are available irrespective of the size of degrees of freedom of chi-squared distribution in the evaluation of clinical significance of Mahalanobis' distance by transforming it into normal deviate.

Study on Liver Function and Serum Immunoglobulin Levels in Type B and Type Non-B Hepatitis: Soo Kun Kim, Eun Yup Lee, Soon Ho Kim; Korean J Cytopathol. 1981;15(3):238-244.

1,138 View
10 Download

Abstract: The author investigated the findings of the liver function tests and serum immunoglobulin 1evels in 25 cases of acute hepatitis, 22 cases of chronic hepatitis and 20 cases of healthy controls in Busan National University Hospital during Jan 1980 and Dec. 1980. Diagnosis was confirmed clinically and pathologically in all the patients. Serum HBsAg was detected by reverse passive hemagglutinnation tests(R-PHA). Serum immunoglobulins were measured by single radial immunodiffusion method. Total protein and albumin daterminations were performed by Biuret and dye binding method(BCG), respectively. SGOT and SGPT were analyzed by Reitman-Frankel method and TTT was measured by Maclagen method. Total bilirubin was measured by modification of the standard Jendrassik-Grof method. The results obtained were summarized as follow : 1) The activities of SGOT and SGPT, the levels of serum total bilirbin and IgG ware significantly higher in type B acute hepatitis than in type non-B one. 2) The levels of IgG and IgM were significantly higher in type non-B chronic hepatitis than in type B one. On the basis of the findings mentioned above, it is suggested that serum immunoglobulin determinations may be useful for differentiation between type B hepatitis and type non B hepatitis.

Study on the Frequency of HBs Antigen Positivity in Transfused Bloods: Kyung Ho Shin; Korean J Cytopathol. 1981;15(3):245-250.

1,185 View
10 Download

Abstract: Chosun university hospital derives mostly its supply of bloods from other blood-donor centers, where all the donated bloods are tested for HBs antigen by means of CIEP method that is known to be less sensitive than RPHA method. Total 1518 bloods supplied from the other blood-donor centers were reexamined for HBs antigen by CIEP and RPHA method. The results are summerized as follows : 1) Out of the total 1518 tested bloods, HBs antigen-positive cases were 31 (2.0%)* by CIEP, 63(4.1%) by RPHA. * These 31 cases were totally HBs antigen-positive by RPHA. 2) Out of the 1487 cases showing HBs antigen negativity by CIEP, 32(2.2%) were HBs antigen-positive by RPHA. 3) Out of the 63 cases showing HBs antigen positivity by RPHA, 21(33.3%) were RPHA titer 5120 and over, and all of these were CIEP-positive. 13(20.6%) were RPHA titer 640 and below, and all of these were CIEP-negative. Out of 29 casts showing HBs antigen positivity at RPHA titer 1280 and 2560, 10 (34.5%) were CIEP-positive and 19(65.5%) were CIEP-negative.

Studies on 11 Cases of Congenital Cystic Pulmonary Diseases: Hoguen Kim, Chan Il Park, Yoo Bock Lee; Korean J Cytopathol. 1981;15(3):251-257.

1,107 View
10 Download

Abstract: Congenital cystic pulmonary diseases represent a spectrum of closely related anomalies that arise during an early stage of embryonic lung bud maturation. Eleven cases of congenital cystic pulmonary diseases were reveiwed and classified based on embryologically oriented histogenesis, which was proposed by Buntain et al. (1974), and is known to be most reasonable. The results were summarized as follows : 1) Among 11 cases of congenital cystic pulmonary diseases, 8 were classified as bronchogenic cysts and 3 were as cystic adenomatoid malformation, and none of the patients with congenital cystic pulmonary disease was classified as pulmonary sequestration or congenital lobar emphysema. 2) In cases of bronchogenic cysts, which were solitary in all, 5 were located at mediastinum, 2 in the lung and one at subcutaneous tissue of the anterior neck. The cysts were lined uniformly by pseudostratified ciliated columnar epithelium. Smooth muscle fibers, submucosal mucous glands and cartilage tissue were frequently observed in the wall of the cysts. 3) The three cases of congenital cystic adenomatoid malformation were subclassified into 2 cases of type Ⅰ and 1 case of type Ⅱ by Stocker's classification(1977). Situs inversus was combined in a case of type Ⅰ congenital cystic adenomatoid malformation as an associated cogenital malformation, which might be the first case reported in the literature. The cysts were lined by ciliated columnar or cuboidal epithelium. Smooth muscle fiber and increased elastic fibers were also observed in the cyst wall.

Estimation of Normal Ranges of Serum Calcium, Zinc, Magnesium and Copper Obtained from the Laboratory Data by the Bhattacharya's Method: Y.K. Kim, J.T. Suh, M.H. Park, S.I. Kim; Korean J Cytopathol. 1981;15(3):258-263.

1,307 View
10 Download

Abstract: Analyses of clinical laboratory data of serum calcium, zinc, magnesium and copper were performed for the estimation of normal ranges by the Bhattacharya's method. The normal ranges of serum calcium, zinc, magnesium and copper are 8.5∼10.9 mg/100 ml, 27.7∼160.5㎍/100ml, 0.9∼2.5 mEq/l and 64.1∼174.5㎍/100ml respectively by atomic, absorption spectrophotometry. The normal ranges estimated are slightly wider than those from text but mean values are included in the reference ranges with good agreements.

Nasopharyngeal Carcinoma -An Analysis of 77 Cases among Koreans and observation on normal histology of nasopharynx in fetuses-: Chul Keun Park, Je G. Chi; Korean J Cytopathol. 1981;15(3):264-272.

956 View
10 Download

Abstract: For the determination of incidence and histopathologic findings of nasopharyngeal carcinoma, a study was made on 77 cases that were diagnosed as nasopharyngeal carcinoma at the Department of Pathology, Seoul National University Hospital during a period of 21 years beginning from the year of 1960. Following findings were observed. 1) The relative incidence of nasopharyngeal carcinoma was 0.4% of those of all malignant tumors, which was significantly lower than those of South China, Republic of China, Kenya and Philippines. Thus Korea appears to belong to low incidence countries as Japan and India. 2) Among 77 cases of nasopharyngeal carcinoma there were 54 males and 23 females with sex ratio of 2.3:1. Twenty six cases(33.8%) occurred in the age group of 50∼59 years. And the next commonest was 40∼49 years(21 cases, 27.3%). The mean age of the total cases was 47.9 years. 3) Histopathologic classification of nasopharyngeal carcinoma showed 37 cases of squamous cell carcinoma, 25 cases of undifferentiated carcinoma, 9 cases of transitional cell carcinoma, 4 cases of lymphoepithelioma and 2 cases of adenocarcinoma. 4) An oberservation on normal nasopharyngeal histology of human fetuses, children and adult was also made. Fetal nasopharynx was covered with pseudostratified cliated columnar epithelium. Focal or diffuse replacement of the ciliated surface epithelium by squamous cells was observed in chi1dhood and appeared to increase its extent as the age progressed.

Two Cases of Pediatric Vaginitis due to Shigella flexneri: Myoung Hee Ahn, Yong Ho Chun, Ki Hong Kim, Seung Hahm Park; Korean J Cytopathol. 1981;15(3):273-276.

1,026 View
10 Download

Abstract: Vaginitis in children is common, but there is a dearth of literature dealing with this problems. It is important to realize that vaginal mucosa of children is thin and neutral in pH, closely proximate to anus and urethra and poor in hygienic status of surrounding area. Most cases of vaginitis in children are considered nonspecific since no obvious etiologic agent can be proven. This report presents two cases of vaginitis due to Shigella flexneri. Both cases showed no diarrhea and urinary Problems. The organisms showed alkaline slant, acid butt on KIA, mannitol positive, indole negative, no H2S and no mobility. Slide agglutination test revealed complete agglutination with polyvalent B antiserum.

Adenomatoid Tumor of the Epididymis -A case of report-: Myung Hee Lee, Ho Jong Chun, Young Jin Park, Chung Hee Chi; Korean J Cytopathol. 1981;15(3):277-281.

1,590 View
10 Download

Abstract: The adenomatoid tumor is rare benign neoplasm in genital tract which is involving both sexs. In male patient the tumors are frequently found in epididymis and tunica vaginalis, while in female patients they are usually located in the fallopian tube but may also be found in the uterus and ovary. Grossly, they are well circumscribed without encapsulation, firm, with whitish-yellow cut surface which is moist and glistening. Microscopically, the tumor is composed of abundant cystic spaces or lymphatic channels including some unclearly defined acinar or glandular structure lined by cells, designated by various authors as endothelial, mesothelial, or epithelial like cells within fibrous background. Only a few cases of adenomatoid tumor have been reported in Korea. As we experienced a case of adenomatoid tumor in epididymis and a brief review of adenomatoid tumor was also made.

Benign and Malignant Struma Ovarii: Eun Sook Chang; Korean J Cytopathol. 1981;15(3):282-287.

957 View
10 Download

Abstract: The presence of small foci of thyroid tissue within benign cystic teratoma(dermoids) of the ovary is not uncommon. The reported incidence of this finding has varied from 1.5 to 28.5%. In these instances the thyroid tissue has no clinical significance. On the other hand, tumors composed largely and/or only thyroid tissue demonstrating physiologic activity or pathologic aberrations are uncommon, and tumors fulfilling one of these criteria may be included as examples of "Struma ovarii." The incidence of malignant change in struma ovarii must be less than 1%. The purpose of this paper is to report 2 cases of benign and malignant struma ovarii treated at Prestyteran medical center, Taegu in January and February, 1981, and to review briefly the literatures.

Acute Megakaryoblastic Leukemia -Report of a case-: Sungyoub Choi, Myoung Hee Park, Sang In Kim; Korean J Cytopathol. 1981;15(3):288-291.

1,356 View
10 Download

Abstract: Acute megakaryoblastic leukemia is a very rare type of leukemia characterized by systemic and rapidly progressive proliferation of atypical and primitive megakaryocytes and their undifferentiated precursors. A case of acute megakaryoblastic leukemia in a 11/2 year-old boy was presented. He had marked anemia and thrombocytopenia and normal white blood cell count with a small number of blasts in peripheral blood. Hepatosplenomegaly was noted. Bone marrow revealed massive proliferation of leukemic blasts admixed with a small number of giant cells suggestive of immature megakaryocytes. PAS stain showed characteristic heavy blocks of PAS positive material in the majority of leukemic cells. As far as we can determine, this is the first such case to be reported in the Korean literature.

Optic Nerve in Anencephaly: Sung Youb Choi, Je G. Chi; Korean J Cytopathol. 1981;15(3):292-295.

1,026 View
10 Download

Abstract: Despite the significant portion of telencephalus is missing in most anencephalics it is fairly cosistent finding that eye these subjects are well formed and preserved. The eye balls were morphologically normal including the retina which is the direct extension of developing telencephalus. In this sense, optic nerve which is merely a white matter tract interconnecting the eye ball to cerebral hemisphere are expected to be in an interesting position of existence. Because cerebral hemisphere is regularly missing in contrast to iconsistently present eye ball. In this communication we studied the optic nerves in anencephalics to determine the spectrum of preservation and also the detailed histology of the remaining optic nerves. Both optic nerves together with dural sheath were dissected from orbit and cranial vault and were serially cut in transverse. There was a rather abrupt discontinuation of optic nerve fibers toward the course of optic chiasm. These findings strongly support the view that the absence of telencephalon in anencephaly is not a primary termination failure but a secondary destruction of cerebral hemisphere during intrauterine life.

A Case of Paraganglioma of the Urinary Bladder: Juck Joon Hwang, In Sun Kim, Seung Young Paik; Korean J Cytopathol. 1981;15(3):296-299.

1,436 View
10 Download

Abstract: Paragangliomas involving the urinary bladder are rare neoplasms which probably account for less than 0.5% of all bladder tumors. The first instance of a paraganglioma of the urinary bladder was reported by Zimmerman et al., in 1953. Since that report, about 40 additional case have appeared in the world literatures and in the domestic area, it was not described nowadays. Recently, the authors experienced a case of paraganglioma arising from the urinary bladder in a 44 years old female, who complained frequency, microhematuria and pain on urination. The reported case illustrated certain histologic variation, histogenetic concepts and clinical features of paraganglioma involving the urinary bladder

Heteropic Gray Matter of the Brain Associated with Myelopathic Arthrogryposis -An autopsy case report-: Jung Il Suh, Moon Hyang Park, Hyo Sook Park, Key Yong Kim*, Je G. Chi**; Korean J Cytopathol. 1981;15(3):300-304.

1,576 View
10 Download

Abstract: The heterotopia of cerebral gray matter is a rare malformation, which could serve as epileptogenic focus in some patients. This anomaly of neuronal migration, however, can occur as a minor isolated phemomenon. Authors observed gary matter heterotopia in frontal white matter, that was incidentally found at an autopsy done in a 7-year old toy who died after corrective surgery for the congenital multiple flexion deformities. The cerebral heterotopia was found near the lateral corner of the frontal horn of the left lateral ventricle, measuring 1 cm. in maximum extent, and was located under the abnormally deep sulcus of the left superior frontal gyrus. Several separate satellite gray nodules were seen in this area. There was another lesion located slightly caudal to the first one at the same side and was composed of a round mass of 5mm size above the head of the caudate nucleus. Microscopically the heterotopic nodules consisted of relatively well formed nerve cells of cortical type. However, their orientation and cellularity were not those of normal cortex. Additionally a marked decrease in the number of anterior horn cells in the spinal cord in the cervical and lumbar levels were seen, indicative of myelopathic nature of arthrogryposis, together with skeletal muscle findings.

First
Prev
Page of 1
Next
Last

Previous issues