Journal of Pathology and Translational Medicine

Case Reports

Extrarenal Malignant Rhabdoid tumor: A Case Report.: Sang Yong Lee, Dae Cheol Kim, Seo Hee Rha, Sook Hee Hong, Tae Hun Kang, Young Ho Lee, Kyoung Jin Nam, Jin Sook Jeong; Korean J Cytopathol. 1996;7(1):69-74.

Abstract PDF: Malignant rhabdoid tumor is a distinct renal tumor in the pediatric age group. It was originally described as a rhabdomyosarcomatoid variant of Wilms tumor. However, subsequent studies failed to confirm myogenous differentiation, so it is now considered to be a distinct and unique type of highly malignant tumor, histogenetically unrelated. Although extrarenal forms of this tumor are rare, several examples have been described in other sites, especially the liver, prostate, paravertebral area, urinary bladder and soft tissue. We experienced a case of malignant rhabdiod tumor located in the intraabdominal cavity in a 10 month-old boy. Smear of peritoneal fluid showed round, polygonal and irregular shaped cells with large nuclei, ample cytoplasm containing Jight pink "to purple cytoplasmic inclusions, and one or a few prominent nucleoli. Immunocytochemistry revealed positivity to cytokeratin, epithelial membrane antigen and vimentin, and negativity to desmin and neuron-specific enolase. These distinct cytologic appearance and immunophenotypes were most consistent with a diagnosis of extrarenal malignant rhabdoid tumor. The cytoplasmic inclusions were correlated with eosinophilic inclusions seen in histologic section and electron microscopy confirmed this interpretation, showing filamentous aggregations in the cytoplasms of the tumor cells.

Lymphatic Cyst of the Adrenal : Report A Case.: Soong Deok Lee, Yong Il Kim; Korean J Pathol. 1991;25(5):491-494.

Abstract: A case of lymphatic cyst of the adrenal gland in a 55-year-old woman is described. The patient presented with vague abdominal pain, and abdominal CT and ultrasonography suggested a pancreatic cyst. The cyst, 10x8x6 cm in size, was found in the left adrenal gland; it was multilocular and septated with thin walls that were lined by a single layer of attenuated cells. The lining cells gave a weak positive immunoreactivity against factor VIII-related antigen and Ulex eurapaeus, and ultrastructural study revealed the lining cells to be of endothelial origin. Together with small tiny proliferative cystic spaces were intermixture of the normal adrenal cortical cells in the transition zone between large cysts and adrenal cortex. No histologic distinction between cystic lymphangioma and lymphangiectatic cyst was obtained; instead, a term of lymphatic cyst seems preferred unless otherwise confirmed. With its classification, the pathogenesis of adrenal lymphatic cysts is reviewed.

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