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1 "Cell dedifferentiation"
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Case Report
Dedifferentiated Extraskeletal Myxoid Chondrosarcoma of the Masticator Space: A Case Report.
Geunyoung Jung, Kyung Ja Cho, Seung Ho Choi, Mi Jung Kim
Korean J Pathol. 2011;45:S101-S105.
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.S1.S101
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AbstractAbstract PDF
We describe a 69-year-old woman who presented with a dedifferentiated extraskeletal myxoid chondrosarcoma arising in the left masticator space. Computed tomography and magnetic resonance imaging revealed a 5 cm sized mass in the left masticator space. Histologically, the tumor consisted of two distinct areas. The less cellular area was a low-grade extraskeletal myxoid chondrosarcoma, composed of strands or cords of uniform spindle cells and abundant myxoid stroma. The more cellular, dedifferentiated area corresponded to a high grade myxofibrosarcoma, consisting of anaplastic tumor cells in myxoid stroma and geographic necrosis. The tumor cells of the former area were positive for S-100 protein, microtubule-associated protein-2 (MAP-2) and class III beta-tubulin, but negative for cytokeratin, smooth muscle actin, and desmin. The tumor cells in the latter, pleomorphic area showed MAP-2 and beta-tubulin immunoreactivity with a high Ki-67 labeling index. Based on its histologic and immunohistochemical features, the tumor was considered a dedifferentiated extraskeletal myxoid chondrosarcoma.

Citations

Citations to this article as recorded by  
  • Extraskeletal myxoid chondrosarcoma of the parotid gland
    NyimiBushabu Fidele, Wu Tianfu, Bing Liu, Yanfang Sun, Zhao Yifang
    Annals of Maxillofacial Surgery.2019; 9(2): 439.     CrossRef
  • Myxoid chondrosarcoma of maxilla: A rare case report
    Hiralal Ash, Ajoy Kumar Shahi, Kabita Chatterjee, Dipankar Samaddar
    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology.2016; 28(3): 273.     CrossRef
  • Maxillo-facial Extraskeletal Myxoid Chondrosarcoma: A Case Report and Discussion
    Ratnadeep Ganguly, Abhishek Mukherjee
    The Korean Journal of Pathology.2011; 45(6): 639.     CrossRef

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