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- Duodenal Adenocarcinoma of Brunner Gland Origin: A Case Report
- Ji Hye Moon, Kyoungbun Lee, Han-Kwang Yang, Woo Ho Kim
- J Pathol Transl Med. 2018;52(3):179-182. Published online December 27, 2017
- DOI: https://doi.org/10.4132/jptm.2017.10.09
- 6,620 View
- 161 Download
- 6 Web of Science
- 6 Crossref
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Abstract
PDF - We report a case of adenocarcinoma originating from the duodenal Brunner glands in a 47-year-old female patient. The lesion was 0.8 cm in extent and located at the posterior wall of the first part of the duodenum. Histologically, the tumor showed transition from non-neoplastic Brunner glands through dysplastic epithelium into adenocarcinoma. The carcinoma cells were strongly positive for MUC6 protein, which is an epithelial marker for the Brunner glands. Tumor protein p53 was overexpressed in the carcinoma cells, but not in the non-neoplastic or dysplastic epithelium. Dystrophic calcification was predominant. This is the first case report of duodenal adenocarcinoma of Brunner gland origin in Korea.
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Citations
Citations to this article as recorded by
- Relationship Between Immunophenotypes, Genetic Profiles, and Clinicopathologic Characteristics in Small Bowel Adenocarcinoma
Aitoshi Hoshimoto, Atsushi Tatsuguchi, Takeshi Yamada, Sho Kuriyama, Ryohei Hamakubo, Takayoshi Nishimoto, Jun Omori, Naohiko Akimoto, Katya Gudis, Keigo Mitsui, Shu Tanaka, Shunji Fujimori, Tsutomu Hatori, Akira Shimizu, Katsuhiko Iwakiri
American Journal of Surgical Pathology.2024; 48(2): 127. CrossRef - Recurrence of Brunner Gland Adenocarcinoma After Duodenectomy and Gastrojejunostomy
Paul Hong, Marcel Ghanim, Abdul Haseeb, Xianzhong Ding, Ayokunle T. Abegunde
ACG Case Reports Journal.2023; 10(6): e01060. CrossRef - HER2-positive adenocarcinoma arising from heterotopic pancreas tissue in the duodenum: A case report
Yoshifumi S Hirokawa, Takashi Iwata, Yoshinaga Okugawa, Koji Tanaka, Hiroyuki Sakurai, Masatoshi Watanabe
World Journal of Gastroenterology.2021; 27(28): 4738. CrossRef - Brunner’s gland adenoma is a rare cause of upper gastrointestinal bleeding: A case report and literature review
Nader Bakheet, Ahmed Cordie, Mohamed Nabil alkady, Ibrahim Naguib
Arab Journal of Gastroenterology.2020; 21(2): 122. CrossRef - Brunner's Gland Adenocarcinoma in an Aged Western Gorilla (Gorilla gorilla)
Jun Sasaki, Ippei Muneuchi, Kanako Ushio, Chihiro Sochi, Youichi Irie, Kazunori Yoshizumi, Waturu Hashimoto
Journal of Comparative Pathology.2020; 181: 47. CrossRef - Adenocarcinoma of the duodenum arising from Brunner’s gland resected by partial duodenectomy: a case report
Tetsuya Mochizuki, Nobuaki Fujikuni, Koichi Nakadoi, Masahiro Nakahara, Kazuaki Tanabe, Shuji Yonehara, Toshio Noriyuki
Surgical Case Reports.2019;[Epub] CrossRef
- Relationship Between Immunophenotypes, Genetic Profiles, and Clinicopathologic Characteristics in Small Bowel Adenocarcinoma
- Multiple Neuroendocrine Tumors in Stomach and Duodenum in a Multiple Endocrine Neoplasia Type 1 Patient
- Bohyun Kim, Han-Kwang Yang, Woo Ho Kim
- J Pathol Transl Med. 2018;52(2):126-129. Published online December 21, 2017
- DOI: https://doi.org/10.4132/jptm.2017.09.16
- 6,754 View
- 144 Download
- 1 Web of Science
- 1 Crossref
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Abstract
PDF
- A 67-year-old woman with a history of subtotal parathyroidectomy, distal pancreatectomy, and total splenectomy 23 years prior underwent surgical gastric resection for neuroendocrine tumors of the stomach and duodenum. Meticulous examination of the entire stomach and duodenum revealed multiple scattered, minute neuroendocrine tumors. To the best of our knowledge, this is the first case report of a patient diagnosed with gastroduodenal neuroendocrine tumors associated with multiple endocrine neoplasia type 1 (MEN 1) in whom complete histologic mapping of the whole gastrectomy specimen was performed. The presence of MEN 1–associated neuroendocrine tumors in the stomach is very rare, but should be considered in patients diagnosed with MEN 1 who present with a new tumor in the stomach.
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Citations
Citations to this article as recorded by- A Case of Asymptomatic Multiple Endocrine Neoplasia Type I with Thymic Carcinoid
Suk Ki Park, Moon Won Lee, In Sub Han, Young Joo Park, Sung Yong Han, Joon Woo Park, Bong Eun Lee, Gwang Ha Kim, Sang Soo Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2019; 19(1): 65. CrossRef
- A Case of Asymptomatic Multiple Endocrine Neoplasia Type I with Thymic Carcinoid
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