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Case Study
- A sinonasal yolk sac tumor in an adult
- Jaehoon Shin, Ji Heui Kim, Kyeong Cheon Jung, Kyung-Ja Cho
- J Pathol Transl Med. 2022;56(3):152-156. Published online January 26, 2022
- DOI: https://doi.org/10.4132/jptm.2021.12.09
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- 3 Web of Science
- 5 Crossref
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Abstract
PDF - Yolk sac tumors (YSTs), which are also called endodermal sinus tumors, are malignant tumors of germ cell origin. These tumors usually occur in the gonads, but 20% of cases have been reported at extragonadal sites. The head and neck is a rarely affected region that accounts for just 1% of all malignant tumors of germ cell origin. In addition, YSTs arise mostly in childhood. We present a rare pathologically pure case of primary adult YST in the sinonasal area. A 45-year-old male patient presented with a rapidly growing mass in the nasal cavity, which caused nasal obstruction and bloody post-nasal drip. The histopathologic features indicated pure YST, and immunohistochemical analysis revealed positive reactivity for Sal-like protein 4 and alpha-fetoprotein. Herein, we discuss the clinical, radiologic, and histologic features of this YST and review other cases of sinonasal YST in adults.
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Citations
Citations to this article as recorded by
- International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors
Edward C. Kuan, Eric W. Wang, Nithin D. Adappa, Daniel M. Beswick, Nyall R. London, Shirley Y. Su, Marilene B. Wang, Waleed M. Abuzeid, Borislav Alexiev, Jeremiah A. Alt, Paolo Antognoni, Michelle Alonso‐Basanta, Pete S. Batra, Mihir Bhayani, Diana Bell,
International Forum of Allergy & Rhinology.2024; 14(2): 149. CrossRef - Yolk sac tumor of postpubertal-type does not exhibit immunohistochemical loss of SMARCB1/INI1 and SMARCA4/BRG1…but choriocarcinoma?
Costantino Ricci, Francesca Ambrosi, Tania Franceschini, Francesca Giunchi, Eugenia Franchini, Francesco Massari, Veronica Mollica, Federico Mineo Bianchi, Maurizio Colecchia, Andres Martin Acosta, Michelangelo Fiorentino
Pathology - Research and Practice.2023; 241: 154269. CrossRef - Pure yolk sac tumor primarily in the nasal cavity: A case report
Zijun Liu, Baohong Wen, Yan Zhang
Asian Journal of Surgery.2023; 46(10): 4712. CrossRef - A case of Yolk sac tumor arising from paranasal sinus
Kaori Shinomura, Munehito Moriyama, Keigo Fujita, Takashi Hirano, Masashi Suzuki
JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY.2023; 33(1): 41. CrossRef - A Novel Successful Case of Nasal and Sinus Yolk Sac Tumor With SMARCB1 (INI-1) Deficiency: A Case Report
Tianyu He, Zhiyu Wang, Hongbo Su, Sihan Li, Zheng He
Cureus.2022;[Epub] CrossRef
- International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors
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