Metastasis to the breast from colorectal carcinoma is rare, only a few cases have been reported in the literature, and no cases have been reported in a young, 28-year-old patient. This report confirms the occurrence of the disease in a younger age group. The patient was referred to the Breast Clinic with a history of a gradually increasing lump in her right breast for two weeks' duration. On clinical examination, a 2-cm firm lump was noted in the upper inner quadrant of the right breast, which was clinically benign; however, histological examination of the breast core biopsy together with immunohistochemistry confirmed metastatic colorectal adenocarcinoma. The primary colorectal carcinoma was later confirmed to be a stage pT4N2M1 tumor, and the Duke stage was C1. Histology with immunohistochemistry is very important in the diagnosis of cases of this nature, but the clinical correlation should be taken into consideration at multidisciplinary team meetings to decide the final management of the patient.

Citations

Citations to this article as recorded by  

• Breast mass as the first sign of metastasis from rectal carcinoma: a case report and review of the literature
  Jiawei Xu, Chao Liu, Chengdong Yu, Tenghua Yu, Fan Fan, Xiaofang Zhang, Chuansheng Huang, Wen Chen, Zhengkui Sun, Meng Zhou
  Frontiers in Oncology.2023;[Epub]     CrossRef
• A case report of multiple bilateral breast metastases after colorectal cancer
  Khaled Arnaout, Nouran Hawa, Sarab Agha, Lama Kadoura, Marwa Aloulou, Kusay Ayoub
  International Journal of Surgery Case Reports.2021; 81: 105759.     CrossRef
• Metastatic Breast Signet-Ring Cell Carcinoma from a Colonic Primary: Review of a Rare Case Report
  Ghazaleh Shaker, Hayedeh Haeri, Behnaz Jahanbin
  International Journal of Cancer Management.2021;[Epub]     CrossRef
• Breast metastasis from rectal cancer with BRAF V600E mutation: a case report with a review of the literature
  Hiroko Hasegawa, Yoko Nagata, Yuko Sakakibara, Masakazu Miyake, Kiyoshi Mori, Norikazu Masuda, Masayuki Mano, Shoichi Nakazuru, Hisashi Ishida, Eiji Mita
  Clinical Journal of Gastroenterology.2020; 13(2): 153.     CrossRef
• Colonic mucinous adenocarcinoma with secondary in the breast: A case report and literature review
  Ameera Balhareth, Abdullah A. AlQatari, Fozan Aldulaijan, Amani Joudeh
  International Journal of Surgery Case Reports.2020; 76: 364.     CrossRef
• Breast metastasis from colorectal cancer treated by multimodal therapy
  Tien-Chan Hsieh, Chao-Wen Hsu
  Medicine.2019; 98(51): e18016.     CrossRef
• A case series of metastases to the breast from extramammary malignancies
  Tanvi Vaidya, Subhash Ramani, Ashita Rastogi
  Indian Journal of Radiology and Imaging.2018; 28(04): 470.     CrossRef
• Metástasis mamaria de un adenocarcinoma mucinoso de colon: descripción de un caso y revisión de la literatura
  Marta Seoane Vigo, María Berdeal Díaz, Lourdes Galán Raposo, Fabio Ares Farpón, Alejandro García Varona, Luis González Crespo
  Revista de Senología y Patología Mamaria.2017; 30(1): 28.     CrossRef
• Metastases of transverse colon cancer to bilateral ovaries (Krukenberg tumor) and the left breast: A case report
  Xin-Yu Luo, Jue Wang, Jia Zhao, Rui Chen, Xiao-Ming Zha
  Oncology Letters.2017; 14(1): 31.     CrossRef
• Metastasis of rectal signet ring adenocarcinoma to the breast in a young woman after 10 years, a rare case report and review of the literature
  Bita Geramizadeh, Ali Mohammad Bananzadeh, Mohammad Reza Sasani, Asieh Khorshidi, Mahsa Marzban
  Cancer Treatment Communications.2016; 7: 58.     CrossRef
• Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature
  Jiten P. Kothadia, Rezina Arju, Monica Kaminski, Arvind Ankireddypalli, Sushil Duddempudi, Jonathan Chow, Shah Giashuddin
  Case Reports in Oncological Medicine.2015; 2015: 1.     CrossRef