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Imaging features of breast cancer molecular subtypes: state of the art
Nariya Cho
J Pathol Transl Med. 2021;55(1):16-25.   Published online November 9, 2020
DOI: https://doi.org/10.4132/jptm.2020.09.03
  • 50,128 View
  • 343 Download
  • 19 Web of Science
  • 18 Crossref
AbstractAbstract PDF
Characterization of breast cancer molecular subtypes has been the standard of care for breast cancer management. We aimed to provide a review of imaging features of breast cancer molecular subtypes for the field of precision medicine. We also provide an update on the recent progress in precision medicine for breast cancer, implications for imaging, and recent observations in longitudinal functional imaging with radiomics.

Citations

Citations to this article as recorded by  
  • Radiomics Integration of Mammography and DCE-MRI for Predicting Molecular Subtypes in Breast Cancer Patients
    Xianwei Yang, Jing Li, Hang Sun, Jing Chen, Jin Xie, Yonghui Peng, Tao Shang, Tongyong Pan
    Breast Cancer: Targets and Therapy.2025; Volume 17: 187.     CrossRef
  • Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer
    Anupama Praveen Kumar, Diego Vicente, Jianfang Liu, Praveen-Kumar Raj-Kumar, Brenda Deyarmin, Xiaoying Lin, Craig D. Shriver, Hai Hu
    Breast Cancer Research and Treatment.2024; 204(1): 15.     CrossRef
  • The association of magnetic resonance imaging features with five molecular subtypes of breast cancer
    Van Thi Nguyen, Duc Huu Duong, Quang Thai Nguyen, Duy Thai Nguyen, Thi Linh Tran, Tra Giang Duong
    European Journal of Radiology Open.2024; 13: 100585.     CrossRef
  • The effect of data resampling methods in radiomics
    Aydin Demircioğlu
    Scientific Reports.2024;[Epub]     CrossRef
  • Treated Primary Cutaneous Malignant Melanoma With Later Metastasis Found in Clinical Presentation of Left Axilla Lymphadenopathy: A Case Report
    Brigitte L Cochran, Sara Eliseo, Austin Vaughn, Tamryn L Van Der Horn, Enzo Ferrara, Jamie Edwards
    Cureus.2024;[Epub]     CrossRef
  • Pushing the envelope in breast conserving surgery − is multiple-wire localization (3 or more wires) associated with increased risk of compromised margins and long-term recurrence?
    Orit Golan, Marian Khatib, Tehillah S. Menes, Vivianne A.R. Freitas, Rivka Kessner, Rina Neeman, Michal Mauda-Havakuk, Diego Mercer, Yoav Amitai
    European Journal of Radiology.2024; 176: 111511.     CrossRef
  • A model combining BI-RADS® descriptors from pre-treatment B-mode breast ultrasound with clinicopathological tumor features shows promise in the prediction of residual disease after neoadjuvant chemotherapy
    Panagiotis Kapetas, Reena Aggarwal, Basmah Altuwayjiri, Katja Pinker, Paola Clauser, Thomas H. Helbich, Pascal A.T. Baltzer
    European Journal of Radiology.2024; 178: 111649.     CrossRef
  • Correlations of Imaging and Therapy in Breast Cancer Based on Molecular Patterns: An Important Issue in the Diagnosis of Breast Cancer
    Oana Maria Burciu, Ioan Sas, Tudor-Alexandru Popoiu, Adrian-Grigore Merce, Lavinia Moleriu, Ionut Marcel Cobec
    International Journal of Molecular Sciences.2024; 25(15): 8506.     CrossRef
  • Access to prior screening mammograms affects the specificity but not sensitivity of radiologists' performance
    J.D. Akwo, P. D. (Yun) Trieu, M.L. Barron, T. Reynolds, S.J. Lewis
    Clinical Radiology.2024; 79(12): e1549.     CrossRef
  • Machine learning-based radiomics prognostic model for patients with proximal esophageal cancer after definitive chemoradiotherapy
    Linrui Li, Zhihui Qin, Juan Bo, Jiaru Hu, Yu Zhang, Liting Qian, Jiangning Dong
    Insights into Imaging.2024;[Epub]     CrossRef
  • LYMPH NODES MORPHOLOGICAL CHANGES AND BREAST CANCER SUBTYPES IN PREDICTION OF METASTASES
    J. N. Akhundova, M. F. Amirova
    World of Medicine and Biology.2024; 20(90): 15.     CrossRef
  • Axillary lymph node changes in different molecular subtypes of breast cancer
    J.N. Akhundova
    Український радіологічний та онкологічний журнал.2024; 32(4): 529.     CrossRef
  • Histogram analysis of multi-model high-resolution diffusion-weighted MRI in breast cancer: correlations with molecular prognostic factors and subtypes
    Yanjin Qin, Feng Wu, Qilan Hu, Litong He, Min Huo, Caili Tang, Jingru Yi, Huiting Zhang, Ting Yin, Tao Ai
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • ASO Author Reflections: Sequence of Treatment in Clinically Node-Negative T1 Triple-Negative Breast Cancer
    Kai Huang, James W. Jakub, Sarah A. McLaughlin
    Annals of Surgical Oncology.2023; 30(13): 8455.     CrossRef
  • Circulating non-coding RNAs as a diagnostic and management biomarker for breast cancer: current insights
    Hamed Hosseinalizadeh, Mehrdad Mahmoodpour, Ammar Ebrahimi
    Molecular Biology Reports.2022; 49(1): 705.     CrossRef
  • MRI as a biomarker for breast cancer diagnosis and prognosis
    Francesca Galati, Veronica Rizzo, Rubina Manuela Trimboli, Endi Kripa, Roberto Maroncelli, Federica Pediconi
    BJR|Open.2022;[Epub]     CrossRef
  • Multiparametric MRI Features of Breast Cancer Molecular Subtypes
    Madalina Szep, Roxana Pintican, Bianca Boca, Andra Perja, Magdalena Duma, Diana Feier, Bogdan Fetica, Dan Eniu, Sorin Marian Dudea, Angelica Chiorean
    Medicina.2022; 58(12): 1716.     CrossRef
  • Circulating tumor cells as prognostic biomarkers in breast cancer: current status and future prospects
    Evagelia Chantzara, Nikolaos Xenidis, Galatea Kallergi, Vassilis Georgoulias, Athanasios Kotsakis
    Expert Review of Molecular Diagnostics.2021; 21(10): 1037.     CrossRef
Short Case Report
Pineal Parenchymal Tumor of Intermediate Differentiation with Gangliocytic Differentiation: A Case Report.
Lee So Maeng
Korean J Pathol. 2009;43(4):364-367.
DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.4.364
  • 3,281 View
  • 28 Download
  • 1 Crossref
AbstractAbstract PDF
A 49-year-old man presented with an extremely rare case of pineal parenchymal tumor with gangliocytic cells, manifesting as progressive gait disturbance and urinary incontinence lasting for one year. Brain MRI revealed a homogenously enhancing mass, measuring 3.5x2.7 x1.7 cm, in the pineal body. The mass compressed the deep cerebral vein with superior displacement, which caused mild obstructive hydrocephalus. Histological examination revealed lobular structures consisting of isomorphic small round cells with stippled chromatin and clear cytoplasm, and less cellular areas having large pleomorphic cells and ganglioid cells. Mitotic figures and tumor necrosis were not evident. Immunohistochemically, the neoplastic cells were positive for neuronal markers (neuron-specific enolase, neurofilament, NeuN and synaptophysin), but not for glial fibrillary acidic protein or S-100. Especially, neurofilament showed diffuse interstitial immunoreactivity with accentuation in a few gangliocytic cells and Ki-67 labeling index (2.5%) was low. Therefore, this case was diagnosed as pineal parenchymal tumor of intermediate differentiation with gangliocytic differentiation.

Citations

Citations to this article as recorded by  
  • Pineal parenchymal tumor of intermediate differentiation: a systematic review and contemporary management of 389 cases reported during the last two decades
    Hajime Takase, Reo Tanoshima, Navneet Singla, Yoshihiko Nakamura, Tetsuya Yamamoto
    Neurosurgical Review.2022; 45(2): 1135.     CrossRef

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