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- Mimicry of Minute Pulmonary Meningothelial-like Nodules to Metastatic Deposits in a Patient with Infiltrating Lobular Carcinoma: A Case Report and Review of the Literature
- Hala Kfoury, Maria A. Arafah, Maha M. Arafah, Sami Alnassar, Waseem Hajjar
- Korean J Pathol. 2012;46(1):87-91. Published online February 23, 2012
- DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.1.87
- 8,876 View
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- 7 Crossref
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Abstract
PDF Minute pulmonary meningothelial-like nodules (MPMNs) are incidentally found lesions in lung resection specimens and autopsies. MPMNs have been associated with neoplastic and non-neoplastic pulmonary conditions and occasionally with extrapulmonary diseases. We report a case of a female patient presenting with invasive lobular carcinoma of the breast and MPMNs, masquerading as metastatic deposits. We describe the morphological, immunohistochemical and ultrastructural features of MPMNs and emphasize the importance of their recognition for proper staging and treatment of patients. To our knowledge, this is the first case in the English literature describing this coexistence.
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- Diffuse pulmonary meningotheliomatosis with pan-TRK expression by immunohistochemistry: a novel finding and potential pitfall
Cansu Karakas, Michael A. Nead, Moises J. Velez
Diagnostic Pathology.2023;[Epub] CrossRef - Diffuse Pulmonary Meningotheliomatosis: Clinic-Pathologic Entity or Indolent Metastasis from Meningioma (or Both)?
Laura Melocchi, Giulio Rossi, Mirca Valli, Maria Cecilia Mengoli, Michele Mondoni, Luigi Lazzari-Agli, Giacomo Santandrea, Fabio Davoli, Chiara Baldovini, Alberto Cavazza, Thomas V. Colby
Diagnostics.2023; 13(4): 802. CrossRef - Pathological diagnosis and immunohistochemical analysis of minute pulmonary meningothelial-like nodules: A case report
Xin Ruan, Liu-Sheng Wu, Zheng-Yang Fan, Qi Liu, Jun Yan, Xiao-Qiang Li
World Journal of Clinical Cases.2023; 11(33): 8022. CrossRef - Benign disease prone to be misdiagnosed as malignant pulmonary nodules: Minute meningothelioid nodules
Xiao‐Xiao Peng, Li‐Xu Yan, Chao Liu, Si‐Yun Wang, Wen‐Feng Li, Xing Gao, Xue‐Wu Wei, Qing Zhou
Thoracic Cancer.2019; 10(5): 1182. CrossRef - Atypical finding of meningothelial-like inclusions in cervical lymph nodes
Rebecca Donkin, Andrew Dettrick, Penelope Wyche, Sarah Grigg
Pathology.2018; 50(7): 785. CrossRef - Minute Pulmonary Meningothelial-Like Nodules Simulating Hematogenous Lung Metastasis: A Case Report
Sang Kook Lee, Gi Jeong Kim, Young Jae Kim, Ah Young Leem, Eu Dong Hwang, Se Kyu Kim, Joon Chang, Young Ae Kang, Song Yee Kim
Tuberculosis and Respiratory Diseases.2013; 75(2): 67. CrossRef - Diffuse Pulmonary Meningotheliomatosis Diagnosed by Transbronchial Lung Biopsy
Roberto Bernabeu Mora, Juan Miguel Sánchez Nieto, Chunshao Hu, Eduardo Alcaraz Mateos, Alberto Giménez Bascuñana, Manuel Rodríguez Rodríguez
Respiration.2013; 86(2): 145. CrossRef
- Diffuse pulmonary meningotheliomatosis with pan-TRK expression by immunohistochemistry: a novel finding and potential pitfall
- An Unusual Meningothelial Element in a Hairy Polyp of the Hard Palate.
- Si Hyong Jang, Kyueng Whan Min, Woong Na, Se Min Jang, Seung Sam Paik
- Korean J Pathol. 2008;42(5):311-313.
- 1,778 View
- 16 Download
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Abstract
PDF
- Hairy polyps are a rare malformations of bigerminal origin that comprise of both ectodermal and mesodermal elements. Meningothelial elements are an extremely rare pathologic finding in hairy polyps. Here we report a case of a hairy polyp with a meningothelial element, which originated from the hard palate. A 1-year-old boy was evaluated for an intraoral mass accompanied by multiple congenital anomalies. A small polypoid mass was noted at the midline of the hard palate. The lesion had central fibroconnective tissue with an unusual stromal component showing reticulated anastomosing pseudovascular patterns. Immunohistochemical staining of the cells lining the pseudovascular spaces and the interstitial cells revealed vimentin and epithelial membrane antigen positivity.
- Secretory Meningioma: A case report.
- Na Hye Myung, Je G Chi
- Korean J Pathol. 1993;27(1):64-68.
- 2,024 View
- 27 Download
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Abstract
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- Secretory meningioma is now a distinctive subtype of mostly meningotheliomatous type of meningioma, which was first defined by Alguacil-Garcia et al. It shows characteristic light-microscopic, ultrastructural, and immunohistochemical features of epithelial and secretory differentiation of meningothelial cells with accumulation of secretory material in the from of hyaline inclusions. A 38-year-old female presented with headache for about 5 months. Magnetic resonance imaging revealed a round multilobated mass, measuring 4x4x3 cm, in the right inferior frontal lobe near the skull base, with surrounding brain edema. Histologically, the tumor basically showed a pattern of meningotheliomatous meningioma but tended to deposit eosinophilic homogeneous material both in the intracellular and extracellular spaces. The shape was globular intracellularly and of variable shape and often conglomerated extracellularly. Histochemical stains revealed the material not of psammomatous but of pseudopsammomatous proteinaceous nature. On electron microscopy, there was no intracellular lumen with secretion but granular electron-dense material of variable size accumulated in the degenerated endoplasmic reticulums, suggestive of proteinaceous secretion.
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