Journal of Pathology and Translational Medicine

Case Reports

Microcystic Adnexal Carcinoma: Report of two cases.: Kyoung Mee Kim, Mi Kyung Jee, Ki Wha Yang, Seok Jin Kang; Korean J Pathol. 1994;28(3):302-306.

Abstract: The clincopathologic features of microcystic adnexal carcinoma are presented. Microcystic adnexal carcinoma is a recently described, very rare neoplasm characterized by a locally aggressive growth pattern, and as far as we know, only two reports on the microcystic adnexal carcinoma have been published in the Korean literature. Recently we experienced two cases of microcystic adnexal carcimoma occurred in a 32-year-old male and 27-year-old female patient. They had 2.5 x 2.0 x 2.0 cm and 1.2 x 0.9 x 0.9 cm sized, slowly growing mass in the glabella and below the lower lip, respectively. The immunohistochemical staining for CEA antigen stains the glandular structures but not pilar structures. So we thinked that this tumor would be originated from primitive adnexal cells differentiating into both pilar and eccrine structures.

Microcystic Adnexal Carcinoma: Report of a case.: Eun Deok Chang, Young Hee Jee, Sun Moo Kim; Korean J Pathol. 1993;27(3):290-292.

Abstract PDF: Microcystic adenxal carcinoma is an unusual, locally aggressive neoplasm that has recently been recongized as a clincopathologic entity. Its histologic appearance includes both pilar and eccrine differentiation. Microscopically, the tumor consisted of small cysts and gland-like structures in superficial portion. In other area, basaloid cell nests and abortive hair follicles in the sclerotic stroma were seen. The cysts were filled with secretory eosinophilic material, which was positively stained with Periodic acid-Schiff and carcinoembryonic antigen. Immuno-peroxidase staining for carcinoembryonic antigen supported the dual differnetiation of this neoplasm. Despite the benign histologic appearance, there was deep and extensive infiltration of the subcutaneous tissue.

Sclerosing Seat Duct Carcinoma: Report of a case.: K H Park, N H Cho, K G Lee; Korean J Pathol. 1989;23(3):382-386.

Abstract PDF: Sclerosing sweat duct carcinoma is unusual and locally aggressive neoplasm that is important to recognize since it may be confused with other benign adnexal neoplasms, particularly syringoma. Authors present a case of sclerosing sweat duct carcinoma in a 21 yearold man. The lesion was a round fresh-colored hard plaque, 1 cm in size, near the right inner eyebrow. The lesion was not fixed. Regional lymph nodes wer not palpated. Histologically, the tumor was composed of small basaloid cell nests and numerous horn cysts in the sclerotic stroma. Some of the small nests showed ductular differentation. The tumor infilturated the dermis, adjacent to the subcutaneous fat tissue and invaded a nerve fiber. Cytologic atypism of the tumor cells was not present. The tumor cell nest is positively stained with carcinoembryonic antigen.

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