E-submission
Search
- Page Path
- HOME > Search
Case Study
- Development of Six Tumors in a Sebaceus Nevus of Jadassohn: Report of a Case
- Serap Gozel, Melahat Donmez, Noyan Can Akdur, Hulya Yikilkan
- Korean J Pathol. 2013;47(6):569-574. Published online December 24, 2013
- DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.6.569
- 8,058 View
- 84 Download
- 20 Crossref
-
Abstract
PDF Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprised of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual for more than four tumors to arise simultaneously within a single sebaceus nevus. Here in, we report a case of a 70-year-old woman with six neoplastic proliferations including a syringocystadenoma papilliferum, pigmented trichoblastoma, tubular apocrine adenoma, sebaceoma, tumors of follicular infundibulum and superficial epithelioma with sebaceus differentiation arising in a long standing nevus sebaceus on the scalp. Our case is extraordinary because a single nevus sebaceus contained six neoplastic proliferations with differentiation toward the folliculosebaceous-apocrine unit.
-
Citations
Citations to this article as recorded by
- Tumor of follicular infundibulum – reappraisal in a series of 28 patients with critical review of the literature
Michael Wilk, Bettina G. Zelger, Bernhard Zelger
JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2024; 22(2): 223. CrossRef - Tumor des follikulären Infundibulums – Neubewertung in einer Serie von 28 Patienten mit kritischer Analyse der Literatur
Michael Wilk, Bettina G. Zelger, Bernhard Zelger
JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2024; 22(2): 223. CrossRef - Adnexal neoplasms of the eye
Roman Drozdowski, Jane M. Grant-Kels, Madina Falcone, Campbell L. Stewart
Clinics in Dermatology.2024; 42(4): 321. CrossRef - Melanotrichoblastoma: sixth case report in the literature
Juliana Polizel Ocanha-Xavier, José Cândido Caldeira Xavier-Júnior
Anais Brasileiros de Dermatologia.2023; 98(6): 871. CrossRef - Multiple secondary neoplasms in nevus sebaceus excision
Travis S. Dowdle, David A. Mehegran, Dylan Maldonado, Cort D. McCaughey
Baylor University Medical Center Proceedings.2022; 35(2): 241. CrossRef - Congenital tumors arising from nevus sebaceous in 2 neonates
Lynette Wei Yi Wee, Bori Born, Sharon Mun Yee Wong, Hui-Ling Chia, Sithach Mey, Suresh Chandran, Mark Jean Aan Koh
JAAD Case Reports.2022; 21: 70. CrossRef - Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review
Yi-Wen Kuo, Jung-Chia Lin, Wei-Hsuan Tsai
Archives of Craniofacial Surgery.2022; 23(2): 83. CrossRef - Multiple rare neoplasms arising from the nevus sebaceous of the scalp: A case report
Deepthi Shetty, Anilkumar Desai, Niranjan Kumar, Dinesh U.S., Aditya Agnihotri, Saurav Bhaduri
Gulhane Medical Journal.2022; 64(2): 197. CrossRef - Syringocystadenoma Papilliferum and Basal Cell Carcinoma Arising in Nevus Sebaceous
Jingjing Jiang, Yujuan Chen, Qi He, Jiao Yang, Zhengzhong Zhang, Hao Yang, Huan Zhang, Chuan Yang
Clinical, Cosmetic and Investigational Dermatology.2022; Volume 15: 2021. CrossRef - Eyelid trichoblastoma – A case series
Gunja Chowdhury, Meghana Tanwar, Usha Kim, Shanthi R. Krishnan
Journal of Clinical Ophthalmology and Research.2021; 9(3): 123. CrossRef - Trilogy Revisited
Anand Bardia, Debajyoti Chatterjee, Keshavamurthy Vinay
Indian Dermatology Online Journal.2021; 12(4): 577. CrossRef - Trichilemmoma coexisting with sebaceous nevus
AngooriG Rao, VangaliS Reddy, M Tejal, M Divya
Indian Dermatology Online Journal.2020; 11(2): 253. CrossRef - Syndromic sebaceous nevus: current findings
Oumama El Ezzi, Anthony S. de Buys Roessingh, Michèle Bigorre, Guillaume Captier
International Journal of Dermatology.2018; 57(5): 599. CrossRef - Syringocystadenoma papilliferum and trichoblastoma arising in the nevus sebaceous
Feifei Wang, Yatong Wu, Zhancai Zheng, Yanping Bai
Indian Journal of Pathology and Microbiology.2018; 61(1): 106. CrossRef - Dermoscopic Analysis of Nevus Sebaceus of Jadassohn: A Study of 13 Cases
Awatef Kelati, Hanane Baybay, Salim Gallouj, Fatima Zahra Mernissi
Skin Appendage Disorders.2017; 3(2): 83. CrossRef - Secondary neoplasms arising from nevus sebaceus: A retrospective study of 450 cases in Taiwan
Ming‐Chun Hsu, Jau‐Yu Liau, Jin‐Liern Hong, Yin Cheng, Yi‐Hua Liao, Jau‐Shiuh Chen, Yi‐Shuan Sheen, Jin‐Bon Hong
The Journal of Dermatology.2016; 43(2): 175. CrossRef - A Histological Snapshot of Hypothetical Multistep Progression From Nevus Sebaceus to Invasive Syringocystadenocarcinoma Papilliferum
Vishwas Parekh, Cesar E. Guerrero, Charles F. Knapp, Craig A. Elmets, Kristopher M. McKay
The American Journal of Dermatopathology.2016; 38(1): 56. CrossRef - Trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum with signet‐ring cells, all arising in nevus sebaceus
Emilie Dore, Megan H. Noe, Brian L. Swick
Journal of Cutaneous Pathology.2015; 42(9): 645. CrossRef - Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy – A case report
Elżbieta Niemczyk, Kazimierz Niemczyk, Jadwiga Małdyk, Lidia Zawadzka-Głos
International Journal of Pediatric Otorhinolaryngology.2015; 79(11): 1932. CrossRef - Fehlbildungen und Nävi des behaarten Kopfes
V. Behle, H. Hamm
Der Hautarzt.2014; 65(12): 1022. CrossRef
- Tumor of follicular infundibulum – reappraisal in a series of 28 patients with critical review of the literature
Original Article
- Nevus Sebaceous with Special Reference on Its Aging Effect.
- Jin Seok Seo, Mi Kyung Kim, Mikyung Kim, Kye Yong Song, Yun Lim Seo, Je G Chi
- Korean J Pathol. 1990;24(4):436-445.
- 1,628 View
- 26 Download
-
Abstract
PDF
- A histopathological study was performed on nevus sebaceus to observe its aging effect based on 75 cases of neuvs sebaceus those were collected during the past 10 years from three university hospitals in Seoul. The results are as follows: 1) Clinical findings The incidence was most frequent in the teenage group. The 75 cases consisted of 41 males and 34 females with a sex ratio of 1.2:1. Most of cases developed in the head and neck areas with 62.7% on the scalp and 29.3% on the face. 2) Histopathologic findings. The epidermal changes such as acanthosis(40%), papillomatosis(73%), hypergranulosis(44%) were most remarkable in the second decade and gradually decreased with aging. The apparent proliferation of sebaceous gland was observed in 73% and it was most prominent in the second decade. Apocrine glands were absent before the first decade but apparently increased after then. Proliferation of eccrine gland was not significant in all the age groups. Mild increase of immature hair follicles were noted in 49% of our cases with gradually decreasing tendency in the older age. The dermal inflammatory infiltrates were noted from the 2nd decade(28%) and thereafter gradually increased. Associated neoplasms were one apocrine adenoma, one sebaceous adenoma, two trichilemmomas and two arteriovenous hemangiomas. The majority of tumors occured in the third decade. Therefore, it is observed that neuvs sebaceous undergoes dynamic histopathologic changes according to the age of patient and later develop various secondary neoplastic changes. The pathogenesis of the nevus sebaceus is suggested to be closely related with developmental anomalies of primitive hair germ units in fetal stage.
First
Prev
