Skip Navigation
Skip to contents

J Pathol Transl Med : Journal of Pathology and Translational Medicine

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
2 "Pathological diagnosis"
Filter
Filter
Article category
Keywords
Publication year
Authors
Funded articles
Reviews
Article image
Molecular characteristics of meningiomas
Young Suk Lee, Youn Soo Lee
J Pathol Transl Med. 2020;54(1):45-63.   Published online January 15, 2020
DOI: https://doi.org/10.4132/jptm.2019.11.05
  • 14,902 View
  • 601 Download
  • 39 Web of Science
  • 43 Crossref
AbstractAbstract PDF
Meningioma is the most common primary intracranial tumor in adults. The grading of meningioma is based on World Health Organization criteria, which rely on histopathological features alone. This grading system is unable to conclusively predict the clinical behavior of these tumors (i.e., recurrence or prognosis in benign or atypical grades). Advances in molecular techniques over the last decade that include genomic and epigenomic data associated with meningiomas have been used to identify genetic biomarkers that can predict tumor behavior. This review summarizes the molecular characteristics of meningioma using genetic and epigenetic biomarkers. Molecular alterations that can predict meningioma behavior may be integrated into the upcoming World Health Organization grading system.

Citations

Citations to this article as recorded by  
  • The Natural History and Treatment of Meningiomas: An Update
    Arsene Daniel Nyalundja, Fabrice Mugisha, Claire Karekezi
    Seminars in Neurology.2024; 44(01): 001.     CrossRef
  • Epidemiology, Genetics, and DNA Methylation Grouping of Hyperostotic Meningiomas
    Gray Umbach, Edwina B. Tran, Charlotte D. Eaton, Abrar Choudhury, Ramin Morshed, Javier E. Villanueva-Meyer, Philip V. Theodosopoulos, Stephen T. Magill, Michael W. McDermott, David R. Raleigh, Ezequiel Goldschmidt
    Operative Neurosurgery.2024;[Epub]     CrossRef
  • Recurrence of Resected Skull Base Meningiomas during Long-term Follow-up: Incidence and Predisposing Factors
    Joshua Ian Macarthur, Cathal John Hannan, Callum Howard, Jane Halliday, Omar Nathan Pathmanaban, Charlotte Hammerbeck-Ward, Scott A. Rutherford, Andrew T. King
    Journal of Neurological Surgery Part B: Skull Base.2024;[Epub]     CrossRef
  • The Evolving Classification of Meningiomas: Integration of Molecular Discoveries to Inform Patient Care
    S. Joy Trybula, Mark W. Youngblood, Constantine L. Karras, Nikhil K. Murthy, Amy B. Heimberger, Rimas V. Lukas, Sean Sachdev, John A. Kalapurakal, James P. Chandler, Daniel J. Brat, Craig M. Horbinski, Stephen T. Magill
    Cancers.2024; 16(9): 1753.     CrossRef
  • Minimally Invasive Approaches in the Surgical Treatment of Intracranial Meningiomas: An Analysis of 54 Cases
    Guenther C. Feigl, Daniel Staribacher, Gavin Britz, Dzmitry Kuzmin
    Brain Tumor Research and Treatment.2024; 12(2): 93.     CrossRef
  • Related mechanisms, current treatments, and new perspectives in meningioma
    Gizem Inetas‐Yengin, Omer Faruk Bayrak
    Genes, Chromosomes and Cancer.2024;[Epub]     CrossRef
  • Clinical application of intraoperative ultrasound superb microvascular imaging in brain tumors resections: contributing to the achievement of total tumoral resection
    Siman Cai, Hao Xing, Yuekun Wang, Yu Wang, Wenbin Ma, Yuxin Jiang, Jianchu Li, Hongyan Wang
    BMC Medical Imaging.2024;[Epub]     CrossRef
  • WHO CNS 5 and meningiomas: What’s new?
    Indranil Chakrabarti, Sujaya Mazumder
    IP Archives of Cytology and Histopathology Research.2024; 9(2): 67.     CrossRef
  • Molecular Developments in Parasellar Tumors and Potential Therapeutic Implications
    Paraskevi Xekouki, Vasiliki Venetsanaki, Georgios Kyriakopoulos, Krystallenia Alexandraki, Anna Angelousi, Gregory Kaltsas
    Endocrine Reviews.2024;[Epub]     CrossRef
  • The Impact of Molecular and Genetic Analysis on the Treatment of Patients with Atypical Meningiomas
    Janez Ravnik, Hojka Rowbottom
    Diagnostics.2024; 14(16): 1782.     CrossRef
  • Differential Expression of Proteins and Genes at the Tumor‐Brain Interface in Invasive Meningioma
    Kornwika Senglek, Chinachote Teerapakpinyo, Nutchawan Jittapiromsak, Pakrit Jittapiromsak, Irin Lertparinyaphorn, Paul Scott Thorner, Shanop Shuangshoti
    Genes, Chromosomes and Cancer.2024;[Epub]     CrossRef
  • DNA methylation profiling of meningiomas highlights clinically distinct molecular subgroups
    Jyotsna Singh, Ravi Sharma, Nidhi Shukla, Priya Narwal, Amit Katiyar, Swati Mahajan, Saumya Sahu, Ajay Garg, Mehar C. Sharma, Ashish Suri, Chitra sarkar, Vaishali Suri
    Journal of Neuro-Oncology.2023; 161(2): 339.     CrossRef
  • Spinal meningiomas, from biology to management - A literature review
    Nicolas Serratrice, Imène Lameche, Christian Attieh, Moussa A Chalah, Joe Faddoul, Bilal Tarabay, Rabih Bou-Nassif, Youssef Ali, Joseph G Mattar, François Nataf, Samar S Ayache, Georges N Abi Lahoud
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression
    Sarah A Cain, Bernard Pope, Stefano Mangiola, Theo Mantamadiotis, Katharine J Drummond
    BMC Cancer.2023;[Epub]     CrossRef
  • Actualización sobre el meningioma: correlación clínico-radiológica y radio-patológica
    A. Navarro-Ballester, M. Aleixandre-Barrachina, S.F. Marco-Doménech
    Radiología.2023; 65(5): 458.     CrossRef
  • SMARCE1-related meningiomas: A clear example of cancer predisposing syndrome
    Erika Fiorentini, Laura Giunti, Andrea Di Rita, Simone Peraio, Carla Fonte, Chiara Caporalini, Anna Maria Buccoliero, Maria Luigia Censullo, Giulia Gori, Alice Noris, Rosa Pasquariello, Roberta Battini, Rossana Pavone, Flavio Giordano, Sabrina Giglio, Ber
    European Journal of Medical Genetics.2023; 66(7): 104784.     CrossRef
  • Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas
    Liguo Ye, Shi’ao Tong, Yaning Wang, Yu Wang, Wenbin Ma
    Journal of Cancer Research and Clinical Oncology.2023; 149(12): 9857.     CrossRef
  • Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers
    A. Basit Khan, Rajan Patel, Malcolm F. McDonald, Eric Goethe, Collin English, Ron Gadot, Arya Shetty, Shervin Hosseingholi Nouri, Arif O. Harmanci, Akdes S. Harmanci, Tiemo J. Klisch, Akash J. Patel
    Journal of Neuro-Oncology.2023; 163(2): 397.     CrossRef
  • DNA methylation meningioma biomarkers: attributes and limitations
    Zhaohui Li, Yufei Gao, Jinnan Zhang, Liang Han, Hang Zhao
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Meningioma: A Biography—Tumor Forever Tied to the Origins and “Soul of Neurosurgery”
    Nolan J. Brown, Zach Pennington, Cathleen C. Kuo, Julian Gendreau, Sachiv Chakravarti, Rohin Singh, Dontré M. Douse, Jamie J. Van Gompel
    World Neurosurgery.2023; 178: 191.     CrossRef
  • Molecular genetic features of meningiomas
    E.S. Makashova, N.V. Lasunin, M.V. Galkin, S.V. Zolotova, K.O. Karandasheva, A.V. Golanov
    Voprosy neirokhirurgii imeni N.N. Burdenko.2023; 87(4): 101.     CrossRef
  • Novel Advances in Treatment of Meningiomas: Prognostic and Therapeutic Implications
    Gerardo Caruso, Rosamaria Ferrarotto, Antonello Curcio, Luisa Metro, Francesco Pasqualetti, Paola Gaviani, Valeria Barresi, Filippo Flavio Angileri, Maria Caffo
    Cancers.2023; 15(18): 4521.     CrossRef
  • Update on meningioma: Clinical-radiological and radio-pathological correlation
    A. Navarro-Ballester, M. Aleixandre-Barrachina, S.F. Marco-Doménech
    Radiología (English Edition).2023; 65(5): 458.     CrossRef
  • Early Preventive Strategies and CNS Meningioma – Is This Feasible? A Comprehensive Review of the Literature
    Daniel Sescu, Aminta Chansiriwongs, Katarzyna Julia Minta, Jyothi Vasudevan, Chandrasekaran Kaliaperumal
    World Neurosurgery.2023; 180: 123.     CrossRef
  • Domestic Animal Models of Central Nervous System Tumors: Focus on Meningiomas
    Michele Tomanelli, Tullio Florio, Gabriela Vargas, Aldo Pagano, Paola Modesto
    Life.2023; 13(12): 2284.     CrossRef
  • The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications
    Stephanie M. Robert, Shaurey Vetsa, Arushii Nadar, Sagar Vasandani, Mark W. Youngblood, Evan Gorelick, Lan Jin, Neelan Marianayagam, E Zeynep Erson-Omay, Murat Günel, Jennifer Moliterno
    Journal of Neuro-Oncology.2022; 156(2): 205.     CrossRef
  • Clinical presentation, diagnostic findings and outcome of dogs undergoing surgical resection for intracranial meningioma: 101 dogs
    Alexander K. Forward, Holger Andreas Volk, Giunio Bruto Cherubini, Tom Harcourt-Brown, Ioannis N. Plessas, Laurent Garosi, Steven De Decker
    BMC Veterinary Research.2022;[Epub]     CrossRef
  • Sphenoid wing meningiomas: peritumoral brain edema as a prognostic factor in surgical outcome
    Abdalrahman Nassar, Volodymyr Smolanka, Andriy Smolanka, Dipak Chaulagain, Oleg Devinyak
    Neurosurgical Review.2022; 45(4): 2951.     CrossRef
  • Potential Molecular Mechanisms of Recurrent and Progressive Meningiomas: A Review of the Latest Literature
    Wenjie Peng, Pei Wu, Minghao Yuan, Bo Yuan, Lian Zhu, Jiesong Zhou, Qian Li
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Case Report: Upper Thoracic Purely Extradural Spinal Meningioma With Nerve Root Attachment: A Case Report and Literature Review
    Zhao-Lin Wang, Jian-Hui Mou, Dong Sun, Peng Liu
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Molecular diagnosis and treatment of meningiomas: an expert consensus (2022)
    Jiaojiao Deng, Lingyang Hua, Liuguan Bian, Hong Chen, Ligang Chen, Hongwei Cheng, Changwu Dou, Dangmurenjiapu Geng, Tao Hong, Hongming Ji, Yugang Jiang, Qing Lan, Gang Li, Zhixiong Liu, Songtao Qi, Yan Qu, Songsheng Shi, Xiaochuan Sun, Haijun Wang, Yongpi
    Chinese Medical Journal.2022;[Epub]     CrossRef
  • Оновлена інформація про менінгіоми крила клиноподібної кістки
    Abdalrahman Nassar, Volodymyr Smolanka
    INTERNATIONAL NEUROLOGICAL JOURNAL.2022; 18(1): 43.     CrossRef
  • The Prognostic Value of Methylation Signatures and NF2 Mutations in Atypical Meningiomas
    Rahmina Meta, Henning B. Boldt, Bjarne W. Kristensen, Felix Sahm, Wenche Sjursen, Sverre H. Torp
    Cancers.2021; 13(6): 1262.     CrossRef
  • Neurofibromatosis Type 2 (NF2) and the Implications for Vestibular Schwannoma and Meningioma Pathogenesis
    Suha Bachir, Sanjit Shah, Scott Shapiro, Abigail Koehler, Abdelkader Mahammedi, Ravi N. Samy, Mario Zuccarello, Elizabeth Schorry, Soma Sengupta
    International Journal of Molecular Sciences.2021; 22(2): 690.     CrossRef
  • Meningioma: A Review of Epidemiology, Pathology, Diagnosis, Treatment, and Future Directions
    Christian Ogasawara, Brandon D. Philbrick, D. Cory Adamson
    Biomedicines.2021; 9(3): 319.     CrossRef
  • The substantial loss of H3K27me3 can stratify risk in grade 2, but not in grade 3 meningioma
    Minsun Jung, Seong-Ik Kim, Ka Young Lim, Jeongmo Bae, Chul-Kee Park, Seung Hong Choi, Sung-Hye Park, Jae-Kyung Won
    Human Pathology.2021; 115: 96.     CrossRef
  • Papillary Meningioma: Case Presentation with Emphasis on Surgical and Medical Therapy of a Rare Variant of Meningioma
    Gerardo Cazzato, Valeria Internò, Antonietta Cimmino, Raffaella Messina, Marco Tucci, Teresa Lettini, Leonardo Resta, Giuseppe Ingravallo
    Diseases.2021; 9(3): 63.     CrossRef
  • An Overview of Managements in Meningiomas
    Lianhua Zhao, Wei Zhao, Yanwei Hou, Cuixia Wen, Jing Wang, Pei Wu, Zaiyu Guo
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • Multi-Omics Analysis in Initiation and Progression of Meningiomas: From Pathogenesis to Diagnosis
    Jiachen Liu, Congcong Xia, Gaiqing Wang
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • Molecular Mechanism and Approach in Progression of Meningioma
    Zhiwei Shao, Lihong Liu, Yanghao Zheng, Sheng Tu, Yuanbo Pan, Sheng Yan, Qichun Wei, Anwen Shao, Jianmin Zhang
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • Multiple meningiomas: does quantity matter? a population-based survival analysis with underlined age and sex differences
    Andres Ramos-Fresnedo, Ricardo A. Domingo, Tito Vivas-Buitrago, Larry Lundy, Daniel M. Trifiletti, Mark E. Jentoft, Amit B. Desai, Alfredo Quiñones-Hinojosa
    Journal of Neuro-Oncology.2020; 149(3): 413.     CrossRef
  • Meningioma: A Review of Clinicopathological and Molecular Aspects
    Kristin Huntoon, Angus Martin Shaw Toland, Sonika Dahiya
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • Neues zur Einteilung und Therapie von Meningeomen
    Corinna Seliger, Wolfgang Wick
    Neurologie up2date.2020; 3(04): 343.     CrossRef
Molecular Testing of Brain Tumor
Sung-Hye Park, Jaekyung Won, Seong-Ik Kim, Yujin Lee, Chul-Kee Park, Seung-Ki Kim, Seung-Hong Choi
J Pathol Transl Med. 2017;51(3):205-223.   Published online May 12, 2017
DOI: https://doi.org/10.4132/jptm.2017.03.08
  • 29,665 View
  • 1,155 Download
  • 39 Web of Science
  • 42 Crossref
AbstractAbstract PDF
The World Health Organization (WHO) classification of central nervous system (CNS) tumors was revised in 2016 with a basis on the integrated diagnosis of molecular genetics. We herein provide the guidelines for using molecular genetic tests in routine pathological practice for an accurate diagnosis and appropriate management. While astrocytomas and IDH-mutant (secondary) glioblastomas are characterized by the mutational status of IDH, TP53, and ATRX, oligodendrogliomas have a 1p/19q codeletion and mutations in IDH, CIC, FUBP1, and the promoter region of telomerase reverse transcriptase (TERTp). IDH-wildtype (primary) glioblastomas typically lack mutations in IDH, but are characterized by copy number variations of EGFR, PTEN, CDKN2A/B, PDGFRA, and NF1 as well as mutations of TERTp. High-grade pediatric gliomas differ from those of adult gliomas, consisting of mutations in H3F3A, ATRX, and DAXX, but not in IDH genes. In contrast, well-circumscribed low-grade neuroepithelial tumors in children, such as pilocytic astrocytoma, pleomorphic xanthoastrocytoma, and ganglioglioma, often have mutations or activating rearrangements in the BRAF, FGFR1, and MYB genes. Other CNS tumors, such as ependymomas, neuronal and glioneuronal tumors, embryonal tumors, meningothelial, and other mesenchymal tumors have important genetic alterations, many of which are diagnostic, prognostic, and predictive markers and therapeutic targets. Therefore, the neuropathological evaluation of brain tumors is increasingly dependent on molecular genetic tests for proper classification, prediction of biological behavior and patient management. Identifying these gene abnormalities requires cost-effective and high-throughput testing, such as next-generation sequencing. Overall, this paper reviews the global guidelines and diagnostic algorithms for molecular genetic testing of brain tumors.

Citations

Citations to this article as recorded by  
  • PTEN regulates expression of its pseudogene in glioblastoma cells in DNA methylation-dependent manner
    Tatyana F. Kovalenko, Bhupender Yadav, Ksenia S. Anufrieva, Tatyana D. Larionova, Tatiana E. Aksinina, Yaroslav A. Latyshev, Soniya Bastola, Michail I. Shakhparonov, Amit Kumar Pandey, Marat S. Pavlyukov
    Biochimie.2024; 219: 74.     CrossRef
  • CDKN2A/B deletion in IDH-mutant astrocytomas: An evaluation by Fluorescence in-situ hybridization
    Manali Ranade, Sridhar Epari, Omshree Shetty, Sandeep Dhanavade, Sheetal Chavan, Ayushi Sahay, Arpita Sahu, Prakash Shetty, Aliasgar Moiyadi, Vikash Singh, Archya Dasgupta, Abhishek Chatterjee, Sadhana Kannan, Tejpal Gupta
    Journal of Neuro-Oncology.2024; 167(1): 189.     CrossRef
  • Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression
    Yeajina Lee, Tamrin Chowdhury, Sojin Kim, Hyeon Jong Yu, Kyung-Min Kim, Ho Kang, Min-Sung Kim, Jin Wook Kim, Yong-Hwy Kim, So Young Ji, Kihwan Hwang, Jung Ho Han, Jinha Hwang, Seong-Keun Yoo, Kyu Sang Lee, Gheeyoung Choe, Jae-Kyung Won, Sung-Hye Park, Yon
    Experimental & Molecular Medicine.2024; 56(4): 975.     CrossRef
  • Liquid biopsy in brain tumors: Potential for impactful clinical applications
    Tania Eid, Lina Ghandour, Joseph Abi Ghanem, Hazem Assi, Rami Mahfouz
    Human Gene.2024; 42: 201333.     CrossRef
  • Diagnostic challenges in complicated case of glioblastoma
    Tatiana Aghova, Halka Lhotska, Libuse Lizcova, Karla Svobodova, Lucie Hodanova, Karolina Janeckova, Kim Vucinic, Martin Gregor, Dora Konecna, Filip Kramar, Jiri Soukup, David Netuka, Zuzana Zemanova
    Pathology and Oncology Research.2024;[Epub]     CrossRef
  • Drugging Hijacked Kinase Pathways in Pediatric Oncology: Opportunities and Current Scenario
    Marina Ferreira Candido, Mariana Medeiros, Luciana Chain Veronez, David Bastos, Karla Laissa Oliveira, Julia Alejandra Pezuk, Elvis Terci Valera, María Sol Brassesco
    Pharmaceutics.2023; 15(2): 664.     CrossRef
  • BrainBase: a curated knowledgebase for brain diseases
    Lin Liu, Yang Zhang, Guangyi Niu, Qianpeng Li, Zhao Li, Tongtong Zhu, Changrui Feng, Xiaonan Liu, Yuansheng Zhang, Tianyi Xu, Ruru Chen, Xufei Teng, Rongqin Zhang, Dong Zou, Lina Ma, Zhang Zhang
    Nucleic Acids Research.2022; 50(D1): D1131.     CrossRef
  • A heat shock protein 90 inhibitor reduces oncoprotein expression and induces cell death in heterogeneous glioblastoma cells with EGFR, PDGFRA, CDK4, and NF1 aberrations
    Kuan-Ta Ho, Pei-Fan Chen, Jian-Ying Chuang, Po-Wu Gean, Yuan-Shuo Hsueh
    Life Sciences.2022; 288: 120176.     CrossRef
  • Bicentric validation of the navigated transcranial magnetic stimulation motor risk stratification model
    Tizian Rosenstock, Levin Häni, Ulrike Grittner, Nicolas Schlinkmann, Meltem Ivren, Heike Schneider, Andreas Raabe, Peter Vajkoczy, Kathleen Seidel, Thomas Picht
    Journal of Neurosurgery.2022; 136(4): 1194.     CrossRef
  • Foramen magnum meningioma presented as cervical myelopathy in a pregnant COVID-19 patient: A case report
    Olivia Josephine Wijaya, Djohan Ardiansyah
    Annals of Medicine and Surgery.2022; 77: 103647.     CrossRef
  • The telomere maintenance mechanism spectrum and its dynamics in gliomas
    Sojin Kim, Tamrin Chowdhury, Hyeon Jong Yu, Jee Ye Kahng, Chae Eun Lee, Seung Ah. Choi, Kyung-Min Kim, Ho Kang, Joo Ho Lee, Soon-Tae Lee, Jae-Kyung Won, Kyung Hyun Kim, Min-Sung Kim, Ji Yeoun Lee, Jin Wook Kim, Yong-Hwy Kim, Tae Min Kim, Seung Hong Choi,
    Genome Medicine.2022;[Epub]     CrossRef
  • A review of predictive, prognostic and diagnostic biomarkers for brain tumours: towards personalised and targeted cancer therapy
    Ernest Osei, Pascale Walters, Olivia Masella, Quinton Tennant, Amber Fishwick, Eugenia Dadzie, Anmol Bhangu, Johnson Darko
    Journal of Radiotherapy in Practice.2021; 20(1): 83.     CrossRef
  • Use of a novel navigable tubular retractor system in 1826 minimally invasive parafascicular surgery (MIPS) cases involving deep-seated brain tumors, hemorrhages and malformations
    Martina M. Cartwright, Penny Sekerak, Joseph Mark, Julian Bailes
    Interdisciplinary Neurosurgery.2021; 23: 100919.     CrossRef
  • Disentangling the therapeutic tactics in GBM: From bench to bedside and beyond
    S. Daisy Precilla, Shreyas S. Kuduvalli, Anitha Thirugnanasambandhar Sivasubramanian
    Cell Biology International.2021; 45(1): 18.     CrossRef
  • Sequencing of a central nervous system tumor demonstrates cancer transmission in an organ transplant
    Marie-Claude Gingras, Aniko Sabo, Maria Cardenas, Abbas Rana, Sadhna Dhingra, Qingchang Meng, Jianhong Hu, Donna M Muzny, Harshavardhan Doddapaneni, Lesette Perez, Viktoriya Korchina, Caitlin Nessner, Xiuping Liu, Hsu Chao, John Goss, Richard A Gibbs
    Life Science Alliance.2021; 4(9): e202000941.     CrossRef
  • Radiogenomics of Gliomas
    Chaitra Badve, Sangam Kanekar
    Radiologic Clinics of North America.2021; 59(3): 441.     CrossRef
  • Chemical analysis of the human brain by imaging mass spectrometry
    Akhila Ajith, Yeswanth Sthanikam, Shibdas Banerjee
    The Analyst.2021; 146(18): 5451.     CrossRef
  • Correlation between Stage and Histopathological Features and Clinical Outcomes in Patients with Glioma Tumors
    Andre Lona, Alfansuri Kadri, Irina Kemala Nasution
    Open Access Macedonian Journal of Medical Sciences.2021; 9(T3): 262.     CrossRef
  • Pediatric Glioma: An Update of Diagnosis, Biology, and Treatment
    Yusuke Funakoshi, Nobuhiro Hata, Daisuke Kuga, Ryusuke Hatae, Yuhei Sangatsuda, Yutaka Fujioka, Kosuke Takigawa, Masahiro Mizoguchi
    Cancers.2021; 13(4): 758.     CrossRef
  • Discovery of clinically relevant fusions in pediatric cancer
    Stephanie LaHaye, James R. Fitch, Kyle J. Voytovich, Adam C. Herman, Benjamin J. Kelly, Grant E. Lammi, Jeremy A. Arbesfeld, Saranga Wijeratne, Samuel J. Franklin, Kathleen M. Schieffer, Natalie Bir, Sean D. McGrath, Anthony R. Miller, Amy Wetzel, Katheri
    BMC Genomics.2021;[Epub]     CrossRef
  • Clinicopathological correlation of glioma patients with respect to immunohistochemistry markers: A prospective study of 115 patients in a Tertiary Care Hospital in North India
    Gitanshu Dahuja, Ashok Gupta, Arpita Jindal, Gaurav Jain, Santosh Sharma, Arvind Kumar
    Asian Journal of Neurosurgery.2021; 16(04): 732.     CrossRef
  • Role of Extracellular Vesicles in Glioma Progression: Deciphering Cellular Biological Processes to Clinical Applications
    Rashmi Rana, Shikha Joon, Kirti Chauhan, Vaishnavi Rathi, Nirmal Kumar Ganguly, Chandni Kumari, Dharmendra Kumar Yadav
    Current Topics in Medicinal Chemistry.2021; 21(8): 696.     CrossRef
  • A comprehensive overview on the molecular biology of human glioma: what the clinician needs to know
    P. D. Delgado-López, P. Saiz-López, R. Gargini, E. Sola-Vendrell, S. Tejada
    Clinical and Translational Oncology.2020; 22(11): 1909.     CrossRef
  • Use of Fluorescence In Situ Hybridization (FISH) in Diagnosis and Tailored Therapies in Solid Tumors
    Natalia Magdalena Chrzanowska, Janusz Kowalewski, Marzena Anna Lewandowska
    Molecules.2020; 25(8): 1864.     CrossRef
  • From Banding to BAM Files
    Adrian M. Dubuc
    Surgical Pathology Clinics.2020; 13(2): 343.     CrossRef
  • Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing
    Ejaz Butt, Sabra Alyami, Tahani Nageeti, Muhammad Saeed, Khalid AlQuthami, Abdellatif Bouazzaoui, Mohammad Athar, Zainularifeen Abduljaleel, Faisal Al-Allaf, Mohiuddin Taher
    F1000Research.2020; 8: 613.     CrossRef
  • Assessment of the non-linear optical behavior of cells for discrimination between normal and malignant glial cells
    Soraya Emamgholizadeh Minaei, Alireza Ghader, Ali Abbasian Ardakani, Samideh Khoei, Mohammad Hosein Majles Ara
    Laser Physics.2020; 30(12): 125601.     CrossRef
  • Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing
    Muhammad Butt, Sabra Alyami, Tahani Nageeti, Muhammad Saeed, Khalid AlQuthami, Abdellatif Bouazzaoui, Mohammad Athar, Zainularifeen Abduljaleel, Faisal Al-Allaf, Mohiuddin Taher
    F1000Research.2019; 8: 613.     CrossRef
  • A Multiplex Quantitative Reverse Transcription Polymerase Chain Reaction Assay for the Detection of KIAA1549–BRAF Fusion Transcripts in Formalin-Fixed Paraffin-Embedded Pilocytic Astrocytomas
    David Bret, Valentin Chappuis, Delphine Poncet, François Ducray, Karen Silva, Fabrice Mion, Alexandre Vasiljevic, Carole Ferraro-Peyret, Carmine Mottolese, Pierre Leblond, Mathieu Gabut, Didier Frappaz, Nathalie Streichenberger, David Meyronet, Pierre-Pau
    Molecular Diagnosis & Therapy.2019; 23(4): 537.     CrossRef
  • A PTPmu Biomarker is Associated with Increased Survival in Gliomas
    Mette L. Johansen, Jason Vincent, Haley Gittleman, Sonya E. L. Craig, Marta Couce, Andrew E. Sloan, Jill S. Barnholtz-Sloan, Susann M. Brady-Kalnay
    International Journal of Molecular Sciences.2019; 20(10): 2372.     CrossRef
  • ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation
    Haydee Martínez, Michelle Nagurney, Zi-Xuan Wang, Charles G Eberhart, Christopher M Heaphy, Mark T Curtis, Fausto J Rodriguez
    Journal of Neuropathology & Experimental Neurology.2019; 78(8): 703.     CrossRef
  • The role of fibroblast growth factors and their receptors in gliomas: the mutations involved
    Vasiliki Georgiou, Vasiliki Gkretsi
    Reviews in the Neurosciences.2019; 30(5): 543.     CrossRef
  • The Role of Next Generation Sequencing in Diagnosis of Brain Tumors: A Review Study
    Sadegh Shirian, Yahya Daneshbod, Saranaz Jangjoo, Amir Ghaemi, Arash Goodarzi, Maryam Ghavideldarestani, Ahmad Emadi, Arman Ai, Akbar Ahmadi, Jafar Ai
    Archives of Neuroscience.2019;[Epub]     CrossRef
  • Applied Precision Cancer Medicine in Neuro-Oncology
    H. Taghizadeh, L. Müllauer, J. Furtner, J. A. Hainfellner, C. Marosi, M. Preusser, G. W. Prager
    Scientific Reports.2019;[Epub]     CrossRef
  • Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas
    Joshua Loewenstern, John Rutland, Corey Gill, Hanane Arib, Margaret Pain, Melissa Umphlett, Yayoi Kinoshita, Russell McBride, Michael Donovan, Robert Sebra, Joshua Bederson, Mary Fowkes, Raj Shrivastava
    Oncotarget.2019; 10(37): 3506.     CrossRef
  • Next generation DNA sequencing of atypical choroid plexus papilloma of brain: Identification of novel mutations in a female patient by Ion Proton
    Mohiuddin Taher, Amal Hassan, Muhammad Saeed, Raid Jastania, Tahani Nageeti, Hisham Alkhalidi, Ghida Dairi, Zainularifeen Abduljaleel, Mohammad Athar, Abdellatif Bouazzaoui, Wafa El‑Bjeirami, Faisal Al‑Allaf
    Oncology Letters.2019;[Epub]     CrossRef
  • Pure mechanistic analysis of additive neuroprotective effects between baicalin and jasminoidin in ischemic stroke mice
    Peng-qian Wang, Qiong Liu, Wen-juan Xu, Ya-nan Yu, Ying-ying Zhang, Bing Li, Jun Liu, Zhong Wang
    Acta Pharmacologica Sinica.2018; 39(6): 961.     CrossRef
  • The Smad4/PTEN Expression Pattern Predicts Clinical Outcomes in Colorectal Adenocarcinoma
    Yumin Chung, Young Chan Wi, Yeseul Kim, Seong Sik Bang, Jung-Ho Yang, Kiseok Jang, Kyueng-Whan Min, Seung Sam Paik
    Journal of Pathology and Translational Medicine.2018; 52(1): 37.     CrossRef
  • Primary brain tumours in adults
    Sarah Lapointe, Arie Perry, Nicholas A Butowski
    The Lancet.2018; 392(10145): 432.     CrossRef
  • Epidemiology and Overview of Gliomas
    Mary Elizabeth Davis
    Seminars in Oncology Nursing.2018; 34(5): 420.     CrossRef
  • Toward Precision Medicine: Promising Areas of Research in Glioma
    Mary Elizabeth Davis, Dana Bossert, Malbora Manne
    Seminars in Oncology Nursing.2018; 34(5): 569.     CrossRef
  • Molecular Basis of Pediatric Brain Tumors
    Alexia Klonou, Christina Piperi, Antonios N. Gargalionis, Athanasios G. Papavassiliou
    NeuroMolecular Medicine.2017; 19(2-3): 256.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine
TOP