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Case Study
- Spindle cell oncocytoma of the sella turcica with anaplastic features and rapid progression in short-term follow-up: a case report with proposal of distinctive radiologic features
- Dong Ja Kim, SangHan Lee, Mee-seon Kim, Jeong-Hyun Hwang, Myong Hun Hahm
- J Pathol Transl Med. 2021;55(3):225-229. Published online March 9, 2021
- DOI: https://doi.org/10.4132/jptm.2021.01.27
- 4,030 View
- 107 Download
- 2 Web of Science
- 3 Crossref
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Abstract
PDF - We present a rare case of spindle cell oncocytoma (SCO) of the sella turcica with malignant histologic features and rapid progression. A 42-year-old woman experienced bilateral blurred vision and was preoperatively misdiagnosed as having a pituitary macroadenoma on magnetic resonance imaging. After surgery, SCO was diagnosed by the histopathologic features of interlacing fascicles of spindle tumor cells with finely granular, eosinophilic cytoplasm. Focal anaplastic changes and necrosis were present. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen, S-100, galectin-3, and thyroid transcription factor 1. Four months later, the tumor had progressed, and second surgery with adjuvant radiotherapy was performed; the patients remains under observation. In this report, we proposed distinctive radiologic features for differential diagnosis between SCO and other pituitary tumors.
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Citations
Citations to this article as recorded by
- Pituitary Spindle Cell Oncocytoma: More than a Grade 1 Tumor?
Jonathan Hammond, Zacharie Gagne, Bojana Mitrovic, Stefano M. Priola
Neurology International.2025; 17(2): 16. CrossRef - Treatment modalities and outcomes of granular cell tumors and spindle cell oncocytomas of the pituitary gland: an analysis of two national cancer databases
A. Yohan Alexander, Giorgos Michalopoulos, Panagiotis Kerezoudis, Jamie J. Van Gompel, Michael J. Link, Maria Peris-Celda
Acta Neurochirurgica.2024;[Epub] CrossRef - Spindle cell oncocytoma, a misdiagnosed rare entity of the pituitary – A case report with review of literature and special emphasis on the morphological differentials
Gittwa Vatsaraj Kottangal, Lilly Madhavan, Shalini Kuruvilla, Kavitha Kanjirakadu Parameswaran, Shehla Basheer Kollathodi
Indian Journal of Pathology and Oncology.2021; 8(4): 533. CrossRef
- Pituitary Spindle Cell Oncocytoma: More than a Grade 1 Tumor?
Brief Case Report
- Sudden Child Death due to Thrombotic Giant Coronary Artery Aneurysms Complicated by Atypical Kawasaki Disease: An Autopsy Case
- DongJa Kim, Man-Hoon Han, SangHan Lee
- J Pathol Transl Med. 2018;52(4):248-251. Published online May 11, 2018
- DOI: https://doi.org/10.4132/jptm.2017.10.23
- 6,242 View
- 133 Download
- 2 Web of Science
- 4 Crossref
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Citations
Citations to this article as recorded by- Autopsy report of a sudden infant death that was strongly suspicious of Kawasaki disease
Yuki Yokouchi, Nanae Asakawa, Hirotaro Iwase, Takeshi Nasu, Kei Takahashi
Pathology International.2024; 74(7): 408. CrossRef - Autoptic Findings in Cases of Sudden Death Due to Kawasaki Disease
Giacomo Visi, Federica Spina, Fabio Del Duca, Alice Chiara Manetti, Aniello Maiese, Raffaele La Russa, Paola Frati, Vittorio Fineschi
Diagnostics.2023; 13(11): 1831. CrossRef - A Systematic Review of Atypical Presentations of Kawasaki Disease
Reza Arjmand, Hedieh Soltani, Nafiseh Yousefi Manesh, Mohammad Ali Shahbabaie
International Journal of Enteric Pathogens.2023; 11(4): 151. CrossRef - Sudden Cardiac Death from Coronary Arteriosclerosis and Coronary Artery Aneurysm in Childhood: An Autopsy Case
Ho Lee, Sang Jae Noh
Korean Journal of Legal Medicine.2022; 46(1): 19. CrossRef
- Autopsy report of a sudden infant death that was strongly suspicious of Kawasaki disease
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