Primary cutaneous mucinous carcinoma (PCMC) is an uncommon tumor of the sweat gland origin. The occurrence of PCMC is mostly in middle-aged and older patients, with a slight male predominance. Most cases of PCMC arise on the head, with a preference for eyelids. The histogenesis of PCMC, whether eccrine or apocrine, remains controversial. We report a rare case of PCMC with secondary extramammary Paget’s disease in the groin of a 75-year-old man, which favored an apocrine origin. Furthermore, based on a review of the literature, we provide several histologic clues that can be used to differentiate PCMC from metastatic mucinous carcinoma.
Citations
Citations to this article as recorded by
Primary cutaneous mucinous carcinoma of the scalp masquerading as a benign dermatological mass – A case report Fadi Alnehlaoui, Nafad Mohamed Lotfy Elhadidi, Shafik Fwakhrji, Shekhar V. Shikare, Majid Hassan Alhammadi, Salman Yousuf Guraya International Journal of Surgery Case Reports.2024; 114: 109175. CrossRef
Primary cutaneous mucinous carcinoma in a periorbital lesion: two case reports and literature review Jun Woo Kim, Sung Eun Kim Archives of Craniofacial Surgery.2024; 25(2): 90. CrossRef
Primary Cutaneous Mucinous Carcinoma: A Review of the Literature Timothy Freeman, Aaron J. Russell, M. Laurin Council Dermatologic Surgery.2023; 49(12): 1091. CrossRef
A Case of Eccrine Mucinous Carcinoma Involving Scalp Ramsha Saleem, Sachin Vaidya Cureus.2021;[Epub] CrossRef
Sebaceous adenoma is a rare solitary or multiple yellow, circumscribed neoplasm consisting of sharply demarcated, proliferating lobules or irregular size and shape that are composed of three cell bypes: basal cells, mature and transitional sebaceous cells. We reported a case of extremely rare sebaceous adenoma arising in caruncle of the left eye in a 78-year-old female. A polypoid tumor nodule, measuring 0.6x0.5 cm, was noticed 6 months before resection.
It was grayish white with granular surface. There is no evidence of associated visceral neoplasm.
Histopathologically, it revealed a lobulated tumor, composed of equal amount of highly differentiated sebaceous and intermediate transitional epithelium with minor participation of basaloid cells. This tumor is thought to be the neoplasm of the sebaceous gland normaly present in the caruncle of the eye rather than ectopic origin.