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Case Studies
A Giant Peritoneal Loose Body
Hyun-Soo Kim, Ji-Youn Sung, Won Seo Park, Youn Wha Kim
Korean J Pathol. 2013;47(4):378-382.   Published online August 26, 2013
DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.4.378
  • 6,994 View
  • 56 Download
  • 15 Crossref
AbstractAbstract PDF

Peritoneal loose bodies (PLBs) are usually discovered incidentally during laparotomy or autopsy. A few cases of giant PLBs presenting with various symptoms have been reported in the literature. Here, we describe a case of a giant PLB incidentally found in the pelvic cavity of a 50-year-old man. Computed tomography revealed a free ovoid mass in the pelvic cavity that consisted of central dense, heterogeneous calcifications and peripheral soft tissue. The mass was an egg-shaped, hard, glistening concretion measuring 7.5×7.0×6.8 cm and weighing 160 g. This concretion consisted of central necrotic fatty tissue surrounded by concentrically laminated, acellular, fibrous material. Small PLBs usually do not require any specific treatment. However, if PLBs cause alimentary or urinary symptoms due to their large size, surgical removal may be recommended. It is essential for clinicians to be aware of this entity and its characteristic features to establish the correct diagnosis.

Citations

Citations to this article as recorded by  
  • Unveiling the rarity: A case report of giant peritoneal loose body
    Abdudin Heru Mehammed, Natnael Alemu Bezabih, Muluken Yifru Gebresilassie, Yohanna Aregawi Hailu, Mengistu Yismie Semahegn, Misganaw Yigletie Damtie
    Radiology Case Reports.2024; 19(11): 5492.     CrossRef
  • A Case of a Fixed Giant Peritoneal Loose Body outside the Peritoneum and near the Rectovesical Excavation
    Kotaro Nanno, Seiichi Shinji, Takeshi Yamada, Akihisa Matsuda, Ryo Ohta, Hiromichi Sonoda, Takuma Iwai, Kohki Takeda, Kazuhide Yonaga, Koji Ueda, Sho Kuriyama, Toshimitsu Miyasaka, Hiromasa Komori, Yoshinobu Shioda, Hiroshi Yoshida
    Journal of Nippon Medical School.2023; 90(3): 276.     CrossRef
  • A Large Intraperitoneal Free Body in a 69-Year-Old Indian Man: a Case Study
    Siddhartha Sankar Bhattacharjee, Promit Chakraborty
    Indian Journal of Surgery.2022; 84(1): 206.     CrossRef
  • Peritoneal loose body presenting as a hepatic mass: A case report and review of the literature
    Yang Wen, Min-jie Shang, Yan-qing Ma, Song-hua Fang, Yuan Chen
    Open Medicine.2021; 16(1): 1356.     CrossRef
  • Peritoneal Loose Body in a Patient With Ampullary Adenocarcinoma
    A.V. Pradeep, Abdul Razik, Ankur Goyal, Atin Kumar, Virinder Kumar Bansal, Asuri Krishna
    ACG Case Reports Journal.2021; 8(11): e00680.     CrossRef
  • Exploratory laparoscopy as first choice procedure for the diagnosis of giant peritoneal loose body: a case report
    RuiBin Li, ZhiHeng Wan, HaoTian Li
    Journal of International Medical Research.2020;[Epub]     CrossRef
  • A rare peritoneal egg: Case report with literature review
    Nilu Malpani Dhoot, Shivaraj Afzalpurkar, Usha Goenka, Vinay Mahendra, Enam Murshed Khan, Arpita Sutradhar, Mahesh Goenka
    Radiology Case Reports.2020; 15(10): 1895.     CrossRef
  • A giant peritoneal loose body impacted in the pelvic cavity, a rare and interesting finding during laparotomy
    Ayad A. Mohammed
    International Journal of Surgery: Global Health.2020; 3(6): e24.     CrossRef
  • Giant Mobile Intraperitoneal Loose Body
    Mohd Ilyas, Mohd Yaqoob Wani, Musaib Ahmad Dar, Feroze A. Shaheen
    ACG Case Reports Journal.2019; 6(1): e00006.     CrossRef
  • Giant peritoneal loose body in a patient with end-stage renal disease
    Nadejda Cojocari, Leonard David
    SAGE Open Medical Case Reports.2018;[Epub]     CrossRef
  • Two giant peritoneal loose bodies were simultaneously found in one patient: A case report and review of the literature
    Qingxing Huang, Aihong Cao, Jun Ma, Zhenhua Wang, Jianhong Dong
    International Journal of Surgery Case Reports.2017; 36: 74.     CrossRef
  • Laparoscopic extraction of a giant peritoneal loose body: Case report and review of literature
    Keiso Matsubara, Yuji Takakura, Takashi Urushihara, Takashi Nishisaka, Toshiyuki Itamoto
    International Journal of Surgery Case Reports.2017; 39: 188.     CrossRef
  • Symptomatic giant peritoneal loose body in the pelvic cavity: A case report
    Andreas Elsner, Mikolaj Walensi, Maya Fuenfschilling, Robert Rosenberg, Robert Mechera
    International Journal of Surgery Case Reports.2016; 21: 32.     CrossRef
  • A Case of a Peritoneal Loose Body with the Maximum Diameter of 50 mm
    Yoshihiro MOCHIZUKI, Hiroshi IINO, Michio HARA, Syugo SHIBA, Makoto SUDO, Naoki OISHI, Tetsuo KONDO
    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association).2016; 77(10): 2552.     CrossRef
  • Giant peritoneal loose body in the pelvic cavity confirmed by laparoscopic exploration: a case report and review of the literature
    Hong Zhang, Yun-zhi Ling, Ming-ming Cui, Zhi-xiu Xia, Yong Feng, Chun-sheng Chen
    World Journal of Surgical Oncology.2015;[Epub]     CrossRef
Papillary Carcinoma of the Thyroid Gland with Nodular Fasciitis-like Stroma
Ki Yong Na, Hyun-Soo Kim, Ji-Youn Sung, Won Seo Park, Youn Wha Kim
Korean J Pathol. 2013;47(2):167-171.   Published online April 24, 2013
DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.2.167
  • 8,574 View
  • 50 Download
  • 11 Crossref
AbstractAbstract PDF

Papillary thyroid carcinoma with nodular fasciitis-like stroma (PTC-NFS) is a rare variant of PTC. The term 'PTC with fibromatosis-like stroma' has been used as a synonym to describe this variant. It is characterized by extensive proliferation of fibroblasts and myofibroblasts in the tumor stroma, which occurs in up to 80% of the tumors. We herein describe a case of PTC-NFS which developed in a 49-year-old woman with the demonstration of findings of ultrasonography, fine needle aspiration cytology and histological examination of the lesion. To characterize the stromal components, we investigated the expression of several immunohistochemical markers which have been shown to be expressed differently in nodular fasciitis (NF) and fibromatosis (FM). The immunostaining results demonstrated nuclear and cytoplasmic accumulation of β-catenin, cytoplasmic transforming growth factor-β expression and nuclear Smad expression in the stromal cells, suggesting that the stromal cells in this case have similar molecular profiles to those of FM rather than NF.

Citations

Citations to this article as recorded by  
  • Papillary thyroid carcinoma with desmoid-type fibromatosis: the clinicopathological features with characteristic imaging and molecular correlation requiring comprehensive treatment
    Haining Huang, Lei Li, Xiaolong Liu, Lihua Zhao, Zhihong Cui, Renya Zhang, Shuai Chen
    Human Pathology.2023; 136: 84.     CrossRef
  • Papillary Thyroid Carcinoma with Desmoid-Type Fibromatosis: Review of Published Cases
    Abdallah Roukain, Stefano La Rosa, Massimo Bongiovanni, Marie Nicod Lalonde, Valérie Cristina, Michael Montemurro, Stephane Cochet, Alexandra Luquain, Peter A. Kopp, Gerasimos P. Sykiotis
    Cancers.2021; 13(17): 4482.     CrossRef
  • Case of medullary thyroid carcinoma with desmoid‐type fibromatosis
    Yoon Ah Cho, Young Lyun Oh
    Pathology International.2020; 70(6): 364.     CrossRef
  • SOX11 expression in a case of papillary thyroid carcinoma with fibromatosis/fasciitis-like stroma containing BRAF c.1799_1801delTGA and CTNNB1 c.133T>C mutations
    Soon Boon Justin Wong, Min En Nga, Michal Michal, Tomas Vanecek, Ju Ee Seet, Fredrik Petersson
    Virchows Archiv.2019; 475(4): 519.     CrossRef
  • Papillary thyroid cancer with extrathyroidal extension of desmoid-type fibromatosis. A case report of an aggressive presentation of an uncommon pathologic entity
    Eve M. Roth, Courtney E. Barrows, Michiya Nishino, Barry Sacks, Per-Olof Hasselgren, Benjamin C. James
    International Journal of Surgery Case Reports.2019; 63: 5.     CrossRef
  • Papillary thyroid carcinoma with nodular fasciitis-like stroma and β-catenin mutations should be renamed papillary thyroid carcinoma with desmoid-type fibromatosis
    Caterina Rebecchini, Antoine Nobile, Simonetta Piana, Rossella Sarro, Bettina Bisig, Sykiotis P Gerasimos, Chiara Saglietti, Maurice Matter, Laura Marino, Massimo Bongiovanni
    Modern Pathology.2017; 30(2): 236.     CrossRef
  • Papillary thyroid carcinoma with desmoid-type fibromatosis: A clinical, pathological, and immunohistochemical study of 14 cases
    Nami Takada, Mitsuyoshi Hirokawa, Masahiro Ito, Aki Ito, Ayana Suzuki, Miyoko Higuchi, Seiji Kuma, Toshitetsu Hayashi, Masao Kishikawa, Shuichi Horikawa, Akira Miyauchi
    Endocrine Journal.2017; 64(10): 1017.     CrossRef
  • A Case of Papillary Thyroid Carcinoma with Fasciitis-like Stroma
    Toshihiko WAKU, Hiroshi SONOBE
    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association).2016; 77(12): 2892.     CrossRef
  • Stromal Modulation and its Role in the Diagnosis of Papillary Patterned Thyroid Lesions
    Sahar Aly Daoud, Reham Shehab El Nemr Esmail, Amal Ahmed Hareedy, Abdullah Khalil
    Asian Pacific Journal of Cancer Prevention.2015; 16(8): 3307.     CrossRef
  • Papillary Thyroid Carcinoma With Nodular Fasciitis–Like Stroma
    Paula S. Ginter, Theresa Scognamiglio
    International Journal of Surgical Pathology.2015; 23(4): 305.     CrossRef
  • Notch and TGF-β/Smad3 pathways are involved in the interaction between cancer cells and cancer-associated fibroblasts in papillary thyroid carcinoma
    Jie Zhang, Yuan Wang, Dan Li, Shanghua Jing
    Tumor Biology.2014; 35(1): 379.     CrossRef
Case Report
Fine Needle Aspiration Cytology of Metastatic Prostatic Adenocarcinoma, Pseudohyperplastic Variant.
Youngmee Kwon, Won Seo Park, Geon Kook Lee, Eun Kyung Hong
Korean J Cytopathol. 2008;19(2):183-187.
DOI: https://doi.org/10.3338/kjc.2008.19.2.183
  • 2,118 View
  • 18 Download
AbstractAbstract PDF
Pseudohyperplastic prostatic adenocarcinoma is a rare histologic variant of prostatic adenocarcinoma that resembles benign nodular hyperplasia. Immunohistochemistry can verify the absence of basal cells, but it is frequently admixed with conventional adenocarcinoma. Because fine needle aspiration cytology is rarely performed in primary prostatic adenocarcinoma, the cytology of the pseudohyperplastic variant has not been described. We experienced a case of metastatic pseudohyperplastic adenocarcinoma in a pulmonary nodule of 75-year-old man. The cytologic smear was mostly composed of large, flat sheets with elongated branching papillae in a clean background. The sheets showed a well-defined honeycomb appearance of tall columnar, regularly arranged monotonous cells with little cytologic atypia. In subsequent prostatic biopsy, pseudohyperplastic variants were identified together with conventional adenocarcinoma of Gleason's grade 3 and 4. The cytologic features of pulmonary nodules were identical to those of pseudohyperplastic components of prostatic adenocarcinoma.

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