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- Pediatric granular cell tumor in the posterior wall of the larynx extending to the trachea
- Jungsuk Ahn, Na Rae Kim, Yong Han Sun
- J Pathol Transl Med. 2020;54(4):336-339. Published online April 15, 2020
- DOI: https://doi.org/10.4132/jptm.2020.02.28
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- 1 Web of Science
- 1 Crossref
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Abstract
PDF - Granular cell tumor (GCT) is a slow-growing benign neoplasm that can be found in any organ. Pediatric laryngotracheal GCT is rare. We experienced a 6-year-old boy suffering from a barking cough and symptoms of stridor and croup for one month. Head and neck computed tomography revealed a protruding mass that occluded 60% of the airway lumen. Under the impression of hemangioma or papilloma, excision revealed a submucosal non-encapsulated mass. Histologically, the mass was composed of sheets of large polyhedralshaped tumor cells containing plump eosinophilic granular cytoplasm and centrally placed, small, bland-appearing nuclei. The tumor cells were positive for S-100 protein, and voluminous eosinophilic cytoplasm was stained by diastase-resistant periodic acid-Schiff. The present report describes a unique case of a huge pediatric laryngeal GCT extending to the subglottic trachea. We also review the clinical course of pediatric laryngotracheal GCT and emphasize the importance of diagnosing GCT in children.
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Citations
Citations to this article as recorded by
- Pediatric granular cell tumor of the larynx: A case report and literature review
Jing Ke, Junwei Xiong, Juhong Zhang, Haiyu Ma, Wei Yuan
Journal of Cancer Research and Therapeutics.2023; 19(4): 1070. CrossRef
- Pediatric granular cell tumor of the larynx: A case report and literature review
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