Characterization of breast cancer molecular subtypes has been the standard of care for breast cancer management. We aimed to provide a review of imaging features of breast cancer molecular subtypes for the field of precision medicine. We also provide an update on the recent progress in precision medicine for breast cancer, implications for imaging, and recent observations in longitudinal functional imaging with radiomics.
Citations
Citations to this article as recorded by
Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer Anupama Praveen Kumar, Diego Vicente, Jianfang Liu, Praveen-Kumar Raj-Kumar, Brenda Deyarmin, Xiaoying Lin, Craig D. Shriver, Hai Hu Breast Cancer Research and Treatment.2024; 204(1): 15. CrossRef
The effect of data resampling methods in radiomics Aydin Demircioğlu Scientific Reports.2024;[Epub] CrossRef
Treated Primary Cutaneous Malignant Melanoma With Later Metastasis Found in Clinical Presentation of Left Axilla Lymphadenopathy: A Case Report Brigitte L Cochran, Sara Eliseo, Austin Vaughn, Tamryn L Van Der Horn, Enzo Ferrara, Jamie Edwards Cureus.2024;[Epub] CrossRef
Histogram analysis of multi-model high-resolution diffusion-weighted MRI in breast cancer: correlations with molecular prognostic factors and subtypes Yanjin Qin, Feng Wu, Qilan Hu, Litong He, Min Huo, Caili Tang, Jingru Yi, Huiting Zhang, Ting Yin, Tao Ai Frontiers in Oncology.2023;[Epub] CrossRef
ASO Author Reflections: Sequence of Treatment in Clinically Node-Negative T1 Triple-Negative Breast Cancer Kai Huang, James W. Jakub, Sarah A. McLaughlin Annals of Surgical Oncology.2023; 30(13): 8455. CrossRef
Circulating non-coding RNAs as a diagnostic and management biomarker for breast cancer: current insights Hamed Hosseinalizadeh, Mehrdad Mahmoodpour, Ammar Ebrahimi Molecular Biology Reports.2022; 49(1): 705. CrossRef
MRI as a biomarker for breast cancer diagnosis and prognosis Francesca Galati, Veronica Rizzo, Rubina Manuela Trimboli, Endi Kripa, Roberto Maroncelli, Federica Pediconi BJR|Open.2022;[Epub] CrossRef
Multiparametric MRI Features of Breast Cancer Molecular Subtypes Madalina Szep, Roxana Pintican, Bianca Boca, Andra Perja, Magdalena Duma, Diana Feier, Bogdan Fetica, Dan Eniu, Sorin Marian Dudea, Angelica Chiorean Medicina.2022; 58(12): 1716. CrossRef
Circulating tumor cells as prognostic biomarkers in breast cancer: current status and future prospects Evagelia Chantzara, Nikolaos Xenidis, Galatea Kallergi, Vassilis Georgoulias, Athanasios Kotsakis Expert Review of Molecular Diagnostics.2021; 21(10): 1037. CrossRef
A 49-year-old man presented with an extremely rare case of pineal parenchymal tumor with gangliocytic cells, manifesting as progressive gait disturbance and urinary incontinence lasting for one year. Brain MRI revealed a homogenously enhancing mass, measuring 3.5x2.7 x1.7 cm, in the pineal body. The mass compressed the deep cerebral vein with superior displacement, which caused mild obstructive hydrocephalus. Histological examination revealed lobular structures consisting of isomorphic small round cells with stippled chromatin and clear cytoplasm, and less cellular areas having large pleomorphic cells and ganglioid cells.
Mitotic figures and tumor necrosis were not evident.
Immunohistochemically, the neoplastic cells were positive for neuronal markers (neuron-specific enolase, neurofilament, NeuN and synaptophysin), but not for glial fibrillary acidic protein or S-100. Especially, neurofilament showed diffuse interstitial immunoreactivity with accentuation in a few gangliocytic cells and Ki-67 labeling index (2.5%) was low. Therefore, this case was diagnosed as pineal parenchymal tumor of intermediate differentiation with gangliocytic differentiation.
Citations
Citations to this article as recorded by
Pineal parenchymal tumor of intermediate differentiation: a systematic review and contemporary management of 389 cases reported during the last two decades Hajime Takase, Reo Tanoshima, Navneet Singla, Yoshihiko Nakamura, Tetsuya Yamamoto Neurosurgical Review.2022; 45(2): 1135. CrossRef