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HOME > J Pathol Transl Med > Volume 26(4); 1992 > Article
Original Article Gastric Choriocarcinoma and Endodermal Sinus Tumor in Collision Tumor.
Eun Kyung Kim, Eun Kyung Hong, Kwang Soo Lee, Jung Dal Lee
Journal of Pathology and Translational Medicine 1992;26(4):405-410
DOI: https://doi.org/
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1Department of Pathology, HanYang University, Seoul, Korea.
2Department of General Surgery, HanYang University, Seoul, Korea.

Both primary choriocarcinoma and endodermal sinus tumor of the stomach are very rare entities. Combination of these two tumors is even rarer, and only a single such case has been reported in English literature. The case had gastric adenocarcinoma in addition to these tumors. We experienced a case of combined, pure choriocarcinoma and endodermal sinus tumor in the stomach of a 74 year-old man. He had no gonadal or any other primary tumor. Huge exophytic tumor was located in the lesser curvature of the body. Two components of the tumor was separated and clearly defined. Human chorionic gonadotropin(HCG) was demonstrated in serum and in tissue sections. Alpha-fetoprotein(alpha-FP) was also demonstrated in serum and in tissue sections. Alpha-fetoprotein(alpha-FP) was also elevated in the serum. Possible tumor origin was speculated.

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