Warning: mkdir(): Permission denied in /home/virtual/lib/view_data.php on line 81

Warning: fopen(upload/ip_log/ip_log_2024-03.txt): failed to open stream: No such file or directory in /home/virtual/lib/view_data.php on line 83

Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84
Immunohistochemical Study of Cytokeratin in Human Trophoblastic Tissue.
Skip Navigation
Skip to contents

J Pathol Transl Med : Journal of Pathology and Translational Medicine

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > J Pathol Transl Med > Volume 26(5); 1992 > Article
Original Article Immunohistochemical Study of Cytokeratin in Human Trophoblastic Tissue.
Jeong Hee Kang, Kang Suek Suh
Journal of Pathology and Translational Medicine 1992;26(5):459-465
DOI: https://doi.org/
Department of Pathology, Pusan National University College of Medicine, Pusan, Korea.
  • 1,555 Views
  • 30 Download
  • 0 Crossref
  • 0 Scopus

The use of human chorionic gonadotropin(hCG), human placental lactogen(hPL) as markers for trophoblastic tissue has been well documented in the literature. However, it is not widely recognized that cytokeratin is a very sensitive and reliable marker for various types of trophoblastic tissue. The authors have studied 15 cases of human placental tissue ranging in age from first to third trimesters. Unlike hCG and hPL, which stain only the syncytiotrophoblast and intermediate trophoblast, cytokeratin(low molecular weight) stains all three types trophoblastic tissue. The staining of placental tissue for cytokeratin is marked and very consistent throughout pregnancy. Because of its high sensitivity and ability to stain cytotrophoblast, it is believed that it could be very useful in detecting trophoblasts of early pregnancy and in the study of the pathologic process of trophoblastic diseases.

Related articles

J Pathol Transl Med : Journal of Pathology and Translational Medicine