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The Korean Journal of Pathology 1993;27(5): 501-503.
Right Atrial Myxoma Showing Granulomatous Lesion with Pulmonary Infart: A case report.
Kun Chang Song, Soon Hee Jung, Dong Hwan Shin
1Department of Pathology, Yonsei University Wonju College of Medicine, Seoul, Korea.
2Department of Patholgy, Yonsei University College of Medicine, Seoul, Korea.
Cardiac myxoma is the most common primary tumor of the heart. The tumor contains a variety of cell types that are thought to arise from a focus of primitive pluripotential mesenchymal cells in the area of the fossa ovalis. Throughout the myxoid stroma, there are variable amounts of reticular fivers, collagen, elastic fibers and smooth muscle cells. A 38-year-old female had right atrial myxoma with multiple pulmonary infarcts. In this case, we experienced an unusual degenerative change in the tumor of granulomatous lesion consisting of hemosiderin pigments, foreign body giant cells and peculiar, spheroid, semilunar or bamboo-shaped degenerated elastic fibers. Microscopically it resembles Gamna-Gandy nodule seen in the spleen of chronic passive congestion.
Key Words: Cardiac myxoma; Granulomatous lesion; Elastic fiber