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The Korean Journal of Pathology 1993;27(5): 518-523.
Papillary Eccrine Adenoma: Histopathological and Immunohistochemical study.
Chan Kum Park
Department of Pathology, College of Medicine, Han Yang University, Seoul, Korea.
Papillary eccrine adenoma is a rare benign sweat gland neoplasm. However, it can show locally aggressive clinical course when it is incompletely removed. A case of papillary eccrine adenoma of the thigh of a 46-year-old woman is reported. Immunohistochemical studies showed that this tumor was diffusely positive for cytokeratin(CAM 5.2), and carcinoembryonic antigen, and focally positive for EMA in the luminal cells of the neoplastic ducts. S-100 protein was not stained in the luminal cells and myoepithelial cells of neoplastic ducts. Papillary eccrine adenoma appears to differentiate toward ductal structures of the eccrine sweat apparatus.
Key Words: Papillary eccrine; Histology; Immunohistochemistry