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HOME > J Pathol Transl Med > Volume 29(4); 1995 > Article
Case Report Primary Teratocarcinoma of the Pineal Gland: A case report.
Kyoung Mee Kim, Eun Jung Lee, Ki Wha Yang, Anhi Lee, Sang In Shim, Sun Moo Kim
Journal of Pathology and Translational Medicine 1995;29(4):527-529
DOI: https://doi.org/
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Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.

Teratocarcinoma is a form of mixed germ cell tumor composed of a mixture of teratoma and embryonal carcinoma. It is rarely found in the brain, but when present it is most commonly found in the pineal region. We investigated a case of primary teratocarcinoma in the pineal region. The patient was a 10 year old boy who had suffered from a bitemporal headache for one month. Brain CT and MRI revealed a rather well defined ovoid heterogenous mass in the pineal gland region, measuring 4.3 x 3.8 x 3.0 cm in size. Microscopically the tumor contained areas of immature teratoma and embryonal carcinoma. Immunohistochemical staining revealed positive reactions for cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and alpha-fetoprotein in the embryonal carcinoma component.

JPTM : Journal of Pathology and Translational Medicine