Warning: fopen(/home/virtual/jptm/journal/upload/ip_log/ip_log_2022-12.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 83 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84 Journal of Pathology and Translational Medicine
Skip Navigation
Skip to contents

JPTM : Journal of Pathology and Translational Medicine

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > J Pathol Transl Med > Volume 31(2); 1997 > Article
Case Report Alzheimer's Disease: Report of two cases.
Hee Sung Kim, Yeon Lim Suh, Kyung Sue Hong, Duk Lyul Na
Journal of Pathology and Translational Medicine 1997;31(2):167-173
DOI: https://doi.org/
  • 1,195 Views
  • 11 Download
  • 0 Crossref
  • 0 Scopus
1Department of Diagnostic Pathology, Samsung Medical Center, Seoul 135-710, Korea.
2Department of Neuropsychiatrics, Samsung Medical Center, Seoul 135-710, Korea.
3Department of Neurology, Samsung Medical Center, Seoul 135-710, Korea.
4Department of Pathology, Seoul National University College of Medicine, Seoul 110-744, Korea.

Alzheimer's disease (AD) is the most common etiology of dementia, that has not been previously reported in Korea. We have experienced two cases of Alzheimer's disease, one occurred in a 53-year-old man with dementia and the other occurred in a 36-year-old woman with a family history of early onset dementia. A neocortical biopsy was done to rule out the cause of dementia and showed diffusely scattered numerous senile plaques and neurofibrillary tangles in cortex of both cases. Interestingly, GFAP, an immunohistochemical stain showed strong positivity in neuritic plaques and the surrounding fibrillary gathering.


JPTM : Journal of Pathology and Translational Medicine