The author has performed H.A.A. and liver function tests with sera from 200 Korean male professional donors and 41 viral hepatitis patients to understand the frequency of H.A.A. in both group and relation between H.A.A. and liver function test. The results were as following: 1. H.A.A. was detected in 10% of Korean professional blood donors. 2. The incidence of H.A.A. positivity was 14.6% in the adult viral hepatitis. 3. In H.A.A. positive donor group, significant increase in mean value and frequency of abnormal value than H.A.A. negative donor group was noted in T.T test. 4. In H.A.A. positive viral hepatitis group, increase in mean value and frequency of abnormal value than H.A.A. negative hepatitis group was noted both in alkaline phosphatase activities and γ-globulin content.